Publications by authors named "Alistair Rust"

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SAVANA: reliable analysis of somatic structural variants and copy number aberrations using long-read sequencing.
Hillary Elrick, Carolin M Sauer, Jose Espejo Valle-Inclan, Katherine Trevers, Melanie Tanguy, Alistair G Rust

Nat Methods· July 2025

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Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution.
Jose Espejo Valle-Inclan, Solange De Noon, Katherine Trevers, Hillary Elrick, Ianthe A E M van Belzen, Alistair G Rust

Cell· January 2025

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Identification of genes that promote PI3K pathway activation and prostate tumour formation.
Jeffrey C Francis, Amy Capper, Alistair G Rust, Klea Ferro, Jian Ning

Oncogene· June 2024

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A HUWE1 defect causes PARP inhibitor resistance by modulating the BRCA1-∆11q splice variant.
Stephen J Pettitt, Nan Shao, Diana Zatreanu, Jessica Frankum, Ilirjana Bajrami, Alistair Rust

Oncogene· September 2023

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Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis.
Aria Vaishnavi, Joseph Juan, Maebh Jacob, Christopher Stehn, Eric E Gardner, Alistair G Rust

Cancer Res· November 2022

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Engineering Cancer Antigen-Specific T Cells to Overcome the Immunosuppressive Effects of TGF-β.
Jonathan D Silk, Rachel J M Abbott, Katherine J Adams, Alan D Bennett, Sara Brett, Alistair G Rust

J Immunol· January 2022

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The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing.
Irene Y Chong, Naureen Starling, Alistair Rust, John Alexander, Lauren Aronson

J Clin Med· January 2021

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Correction: Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer.
Steve Wagner, Georgios Vlachogiannis, Alexis De Haven Brandon, Melanie Valenti, Gary Box, Alistair G Rust

Oncogene· July 2019

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A lentiviral vector-based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma.
Marco Ranzani, Constantine Alifrangis, Nicola A Thompson, Alistair G Rust, Amin Allahyar

Pigment Cell Melanoma Res· March 2019

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Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer.
Steve Wagner, Georgios Vlachogiannis, Alexis De Haven Brandon, Melanie Valenti, Gary Box, Alistair G Rust

Oncogene· March 2019

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FFPE breast tumour blocks provide reliable sources of both germline and malignant DNA for investigation of genetic determinants of individual tumour responses to treatment.
Anna Wilkins, Ritika Chauhan, Alistair Rust, Alex Pearson, Frances Daley

Breast Cancer Res Treat· August 2018

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Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers.
Saira Khalique, Kalnisha Naidoo, Ayoma D Attygalle, Divya Kriplani, Frances Daley, Alistair G Rust

J Pathol Clin Res· July 2018

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Capture Hi-C identifies putative target genes at 33 breast cancer risk loci.
Joseph S Baxter, Olivia C Leavy, Nicola H Dryden, Sarah Maguire, Nichola Johnson, Alistair G Rust

Nat Commun· March 2018

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Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression.
Roberto Rangel, Song-Choon Lee, Kenneth Hon-Kim Ban, Liliana Guzman-Rojas, Michael B Mann, Alistair G Rust

Proc Natl Acad Sci U S A· November 2016

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Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq.
Karen M Mann, Justin Y Newberg, Michael A Black, Devin J Jones, Felipe Amaya-Manzanares, Alistair G Rust

Nat Biotechnol· September 2016

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A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.
Rebecca E McIntyre, Jérôme Nicod, Carla Daniela Robles-Espinoza, John Maciejowski, Na Cai, Alistair G Rust

G3 (Bethesda)· August 2016

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Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer.
Imran Ahmad, Ernest Mui, Laura Galbraith, Rachana Patel, Ee Hong Tan, Alistair G Rust

Proc Natl Acad Sci U S A· July 2016

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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.
Jerry W. Shay, Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Alistair G. Rust

BMC Genomics· July 2016

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Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development.
Haruna Takeda, Alistair G Rust, Jerrold M Ward, Christopher Chin Kuan Yew, Nancy A Jenkins

Proc Natl Acad Sci U S A· April 2016

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Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes.
Mamunur Rashid, Andrej Fischer, Cathy H Wilson, Jessamy Tiffen, Alistair G Rust

J Pathol· January 2016

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A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression.
George Giotopoulos, Louise van der Weyden, Hikari Osaki, Alistair G Rust, Paolo Gallipoli

J Exp Med· September 2015

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Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia.
Louise van der Weyden, George Giotopoulos, Kim Wong, Alistair G Rust, Carla Daniela Robles-Espinoza

BMC Cancer· August 2015

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PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia.
Jinjun Dang, Lei Wei, Jeroen de Ridder, Xiaoping Su, Alistair G Rust

Blood· June 2015

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Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma.
Michael B Mann, Michael A Black, Devin J Jones, Jerrold M Ward, Christopher Chin Kuan Yew, Alistair G Rust

Nat Genet· May 2015

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BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model.
Daniele Perna, Florian A Karreth, Alistair G Rust, Pedro A Perez-Mancera, Mamunur Rashid

Proc Natl Acad Sci U S A· February 2015

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