Publications by authors named "Andrew Nash"

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Structural basis for the inhibition of βFXIIa by garadacimab.
Ieva Drulyte, Rajesh Ghai, Saw Yen Ow, Eugene A Kapp, Adam J Quek, Andrew D Nash

Structure· October 2024

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Inhibition of VEGF-B signaling prevents non-alcoholic fatty liver disease development by targeting lipolysis in the white adipose tissue.
Annelie Falkevall, Annika Mehlem, Erika Folestad, Frank Chenfei Ning, Óscar Osorio-Conles, Andrew Nash

J Hepatol· May 2023

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HDX-MS study on garadacimab binding to activated FXII reveals potential binding interfaces through differential solvent exposure.
Saw Yen Ow, Eugene A Kapp, Vesna Tomasetig, Anton Zalewski, Jason Simmonds, Andrew D Nash

MAbs· January 2023

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Anti-β mAb CSL311 inhibits human nasal polyp pathophysiology in a humanized mouse xenograft model.
Kwok Ho Yip, Nicholas J Wilson, Harshita Pant, Christopher L Brown, Samantha Busfield, Andrew D Nash

Allergy· February 2020

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Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells.
Marc Rigau, Simone Ostrouska, Thomas S Fulford, Darryl N Johnson, Katherine Woods, Andrew D Nash

Science· February 2020

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A potential association between IL-3 and type I and III interferons in systemic lupus erythematosus.
Shereen Oon, Katherine Monaghan, Milica Ng, Alberta Hoi, Eric Morand, Andrew D Nash

Clin Transl Immunology· December 2019

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Lack of Fractalkine Receptor on Macrophages Impairs Spontaneous Recovery of Ribbon Synapses After Moderate Noise Trauma in C57BL/6 Mice.
Tejbeer Kaur, Anna C Clayman, Andrew J Nash, Angela D Schrader, Mark E Warchol

Front Neurosci· June 2019

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Antibody-mediated inhibition of FXIIa blocks downstream bradykinin generation.
Helen Cao, Mark Biondo, Hadi Lioe, Samantha Busfield, Veronika Rayzman, Andrew Nash

J Allergy Clin Immunol· October 2018

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Role of the β Common (βc) Family of Cytokines in Health and Disease.
Timothy R Hercus, Winnie L T Kan, Sophie E Broughton, Denis Tvorogov, Hayley S Ramshaw, Andrew D Nash

Cold Spring Harb Perspect Biol· June 2018

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A neutralizing anti-G-CSFR antibody blocks G-CSF-induced neutrophilia without inducing neutropenia in nonhuman primates.
Karen Scalzo-Inguanti, Katherine Monaghan, Kirsten Edwards, Eva Herzog, Danijela Mirosa, Andrew Nash

J Leukoc Biol· August 2017

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An Anti-VEGF-B Antibody Fragment Induces Regression of Pre-Existing Blood Vessels in the Rat Cornea.
Yazad D Irani, Pierre D Scotney, Sonja Klebe, Lauren A Mortimer, Andrew D Nash

Invest Ophthalmol Vis Sci· July 2017

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Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease.
Annelie Falkevall, Annika Mehlem, Isolde Palombo, Benjamin Heller Sahlgren, Lwaki Ebarasi, Andrew Nash

Cell Metab· March 2017

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CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors.
Con Panousis, Urmi Dhagat, Kirsten M Edwards, Veronika Rayzman, Matthew P Hardy, Andrew D Nash

MAbs· December 2016

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Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis.
Ian K Campbell, David Leong, Kirsten M Edwards, Veronika Rayzman, Milica Ng, Andrew D Nash

J Immunol· December 2016

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A therapeutic gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis.
Neil M O'Brien-Simpson, James A Holden, Jason C Lenzo, Yan Tan, Gail C Brammar, Andrew Nash

NPJ Vaccines· December 2016

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A cytotoxic anti-IL-3Rα antibody targets key cells and cytokines implicated in systemic lupus erythematosus.
Shereen Oon, Huy Huynh, Tsin Yee Tai, Milica Ng, Katherine Monaghan, Andrew D Nash

JCI Insight· May 2016

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Species Cross-Reactivity of Antibodies Used to Treat Ophthalmic Conditions.
Yazad Irani, Pierre Scotney, Andrew Nash, Keryn A Williams

Invest Ophthalmol Vis Sci· February 2016

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Prospects for treatment of Porphyromonas gingivalis-mediated disease - immune-based therapy.
Eric C Reynolds, Neil O'Brien-Simpson, Tony Rowe, Andrew Nash, Jackie McCluskey

J Oral Microbiol· September 2015

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Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody.
Sophie E Broughton, Timothy R Hercus, Matthew P Hardy, Barbara J McClure, Tracy L Nero, Andrew D Nash

Cell Rep· July 2014

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Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362.
Sophie E Broughton, Timothy R Hercus, Tracy L Nero, Urmi Dhagat, Catherine M Owczarek, Andrew D Nash

Acta Crystallogr F Struct Biol Commun· March 2014

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A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk.
Magnus Larsson, Veronika Rayzman, Marc W Nolte, Katrin F Nickel, Jenny Björkqvist, Andrew D Nash

Sci Transl Med· February 2014

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Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically.
Tracy L Putoczki, Stefan Thiem, Andrea Loving, Rita A Busuttil, Nicholas J Wilson, Andrew Nash

Cancer Cell· August 2013

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Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1.
Nicholas T Redpath, Yibin Xu, Nicholas J Wilson, Louis J Fabri, Manuel Baca, Andrew D Nash

Biochem J· April 2013

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Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes.
Carolina E Hagberg, Annika Mehlem, Annelie Falkevall, Lars Muhl, Barbara C Fam, Andrew Nash

Nature· October 2012

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VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis.
Fan Zhang, Zhongshu Tang, Xu Hou, Johan Lennartsson, Yang Li, Andrew Nash

Proc Natl Acad Sci U S A· April 2009

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