Publications by authors named "Anthony Cacciapuoti"

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The optimization of pyridazinone series of glucan synthase inhibitors.
Rongze Kuang, Heping Wu, Pauline C Ting, Robert G Aslanian, Jianhua Cao, Anthony Cacciapuoti

Bioorg Med Chem Lett· August 2012

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Lead optimization of a sulfonylurea-based piperazine pyridazinone series of glucan synthase inhibitors.
Andrew J Zych, Sang Q Lam, David M Jenkins, R Jason Herr, Pauline C Ting, Anthony Cacciapuoti

Bioorg Med Chem Lett· July 2012

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Discovery of a novel class of orally active antifungal beta-1,3-D-glucan synthase inhibitors.
Scott S Walker, Yiming Xu, Ilias Triantafyllou, Michelle F Waldman, Cara Mendrick, Anthony Cacciapuoti

Antimicrob Agents Chemother· November 2011

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The synthesis and structure-activity relationship of pyridazinones as glucan synthase inhibitors.
Pauline C Ting, Rongze Kuang, Heping Wu, Robert G Aslanian, Jianhua Cao, Anthony Cacciapuoti

Bioorg Med Chem Lett· March 2011

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Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048).
Amin A Nomeir, Birendra N Pramanik, Larry Heimark, Frank Bennett, John Veals, Anthony Cacciapuoti

J Mass Spectrom· April 2008

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Efficacy of posaconazole and amphotericin B in experimental invasive pulmonary aspergillosis in dexamethasone immunosuppressed rats.
Andrew J Ullmann, Erik Krammes, Sita Sommer, Ines Buschmann, Bernhard Jahn-Muehl, Anthony Cacciapuoti

J Antimicrob Chemother· November 2007

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Interaction between posaconazole and caspofungin in concomitant treatment of mice with systemic Aspergillus infection.
Anthony Cacciapuoti, Judith Halpern, Cara Mendrick, Christine Norris, Reena Patel

Antimicrob Agents Chemother· July 2006

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Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048 (1), and the discovery of posaconazole [Sch 56592; 2 or (S,S)-5].
Frank Bennett, Anil K Saksena, Raymond G Lovey, Yi-Tsung Liu, Naginbhai M Patel, Anthony Cacciapuoti

Bioorg Med Chem Lett· January 2006

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Inactivation of sterol Delta5,6-desaturase attenuates virulence in Candida albicans.
Andrew S Chau, Maya Gurnani, Robyn Hawkinson, Michel Laverdiere, Anthony Cacciapuoti

Antimicrob Agents Chemother· September 2005

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Interaction between posaconazole and amphotericin B in concomitant treatment against Candida albicans in vivo.
Anthony Cacciapuoti, Maya Gurnani, Judith Halpern, Christine Norris, Reena Patel

Antimicrob Agents Chemother· February 2005

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Effect of granulocyte colony-stimulating factor combination therapy on efficacy of posaconazole (SCH56592) in an inhalation model of murine pulmonary aspergillosis.
Andriani C Patera, Frederick Menzel, Craig Jackson, Joan K Brieland, Judy Halpern, Anthony Cacciapuoti

Antimicrob Agents Chemother· August 2004

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Activity of posaconazole combined with amphotericin B against Aspergillus flavus infection in mice: comparative studies in two laboratories.
Laura K Najvar, Anthony Cacciapuoti, Steve Hernandez, Judith Halpern, Rosie Bocanegra

Antimicrob Agents Chemother· March 2004

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Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis.
D Andes, K Marchillo, R Conklin, Gopal Krishna, Farkad Ezzet, Anthony Cacciapuoti

Antimicrob Agents Chemother· January 2004

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Synthesis and antifungal activity of the 2,2,5-tetrahydrofuran regioisomers of SCH 51048.
Raymond G Lovey, Anil K Saksena, Viyyoor M Girijavallabhan, Paul Blundell, Henry Guzik, Anthony Cacciapuoti

Bioorg Med Chem Lett· July 2002

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