Publications by authors named "April Smith Torhan"

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Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models.
Robbie L McLeod, Deen B Tulshian, Donald C Bolser, Geoffrey B Varty, Marco Baptista, April Smith-Torhan

Eur J Pharmacol· March 2010

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Effect of a novel NOP receptor agonist (SCH 225288) on guinea pig irritant-evoked, feline mechanically induced and canine infectious tracheobronchitis cough.
Robbie L McLeod, Deen B Tulshian, Ginny D Ho, Xiomara Fernandez, Donald C Bolser, April Smith-Torhan

Pharmacology· December 2009

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Identification of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the management of cough and anxiety.
Shu-Wei Yang, Ginny Ho, Deen Tulshian, William J Greenlee, Zheng Tan, April Smith-Torhan

Bioorg Med Chem Lett· May 2009

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The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety.
Ginny D Ho, John Anthes, Ana Bercovici, John P Caldwell, Kuo-Chi Cheng, April Smith Torhan

Bioorg Med Chem Lett· May 2009

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The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510).
Geoffrey B Varty, Sherry X Lu, Cynthia A Morgan, Mary E Cohen-Williams, Robert A Hodgson, April Smith-Torhan

J Pharmacol Exp Ther· August 2008

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Cloning and characterization of the hamster and guinea pig nicotinic acid receptors.
April Smith Torhan, Boonlert Cheewatrakoolpong, Lia Kwee, Scott Greenfeder

J Lipid Res· September 2007

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Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 2.
Ginny D Ho, Ana Bercovici, Deen Tulshian, William J Greenlee, Ahmad Fawzi, April Smith Torhan

Bioorg Med Chem Lett· June 2007

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Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1.
Ginny D Ho, Ana Bercovici, Deen Tulshian, William J Greenlee, Ahmad Fawzi, April Smith Torhan

Bioorg Med Chem Lett· June 2007

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Metabolism-based identification of a potent thrombin receptor antagonist.
Martin C Clasby, Samuel Chackalamannil, Michael Czarniecki, Dario Doller, Keith Eagen, April Smith-Torhan

J Med Chem· January 2007

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Modification of the clozapine structure by parallel synthesis.
Jing Su, Haiqun Tang, Brian A McKittrick, Duane A Burnett, Hongtao Zhang, April Smith-Torhan

Bioorg Med Chem Lett· September 2006

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Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig.
Robbie L McLeod, Yanlin Jia, Xiomara Fernandez, Leonard E Parra, Xin Wang, April Smith-Torhan

Pharmacology· July 2004

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Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats.
Margaret van Heek, Constance Farley, Douglas S Compton, Lizbeth M Hoos, April Smith-Torhan

Br J Pharmacol· April 2003

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