Publications by authors named "Barbara Haertlein"

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Cooperative antithrombotic effect from the simultaneous inhibition of thrombin and factor Xa.
Edward C Giardino, Barbara J Haertlein, Lawrence de Garavilla, Michael J Costanzo, Bruce P Damiano

Blood Coagul Fibrinolysis· March 2010

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Dual inhibition of cathepsin G and chymase is effective in animal models of pulmonary inflammation.
Bruce E Maryanoff, Lawrence de Garavilla, Michael N Greco, Barbara J Haertlein, Grace I Wells

Am J Respir Crit Care Med· February 2010

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Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits.
Edward C Lawson, Diane K Luci, Shyamali Ghosh, William A Kinney, Charles H Reynolds, Barbara J Haertlein

J Med Chem· December 2009

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Carba-nucleosides as potent antagonists of the adenosine 5'-diphosphate (ADP) purinergic receptor (P2Y12 on human platelets.
Hong Ye, Cailin Chen, Han-Cheng Zhang, Barbara Haertlein, Tom J Parry

ChemMedChem· May 2008

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Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif.
Kevin D Kreutter, Tianbao Lu, Lily Lee, Edward C Giardino, Sharmila Patel, Barbara J Haertlein

Bioorg Med Chem Lett· May 2008

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Phenylpiperidine-benzoxazinones as urotensin-II receptor antagonists: synthesis, SAR, and in vivo assessment.
Diane K Luci, Shyamali Ghosh, Charles E Smith, Jenson Qi, Yuanping Wang, Barbara Haertlein

Bioorg Med Chem Lett· December 2007

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A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
Lawrence de Garavilla, Michael N Greco, Narayanasami Sukumar, Zhi-Wei Chen, Agustin O Pineda, Barbara J Haertlein

J Biol Chem· May 2005

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In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
Michael J Costanzo, Harold R Almond, Leonard R Hecker, Mary R Schott, Stephen C Yabut, Barbara J Haertlein

J Med Chem· March 2005

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