Publications by authors named "Barbara Mroczkowski"

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Comparative Oncology Assessment of a Novel Inhibitor of Valosin-Containing Protein in Tumor-Bearing Dogs.
Amy K LeBlanc, Christina N Mazcko, Timothy M Fan, David M Vail, Brian K Flesner, Barbara Mroczkowski

Mol Cancer Ther· October 2022

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Sulforaphane is Synergistic with CB-5083 and Inhibits Colony Formation of CB-5083-Resistant HCT116 Cells.
Feng Wang, Shan Li, William M Rosencrans, Kai-Wen Cheng, Gordon M Stott, Barbara Mroczkowski

ChemMedChem· June 2022

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2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition.
Soojay Banerjee, Alberto Bartesaghi, Alan Merk, Prashant Rao, Stacie L Bulfer, Barbara Mroczkowski

Science· February 2016

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Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).
J Jean Cui, Michelle Tran-Dubé, Hong Shen, Mitchell Nambu, Pei-Pei Kung, Barbara Mroczkowski

J Med Chem· September 2011

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Structure-based design of novel human Pin1 inhibitors (I).
Chuangxing Guo, Xinjun Hou, Liming Dong, Eleanor Dagostino, Samantha Greasley, Barbara Mroczkowski

Bioorg Med Chem Lett· October 2009

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Phase 0 clinical trials: conceptions and misconceptions.
Shivaani Kummar, Larry Rubinstein, Robert Kinders, Ralph E Parchment, Martin E Gutierrez, Barbara Mroczkowski

Cancer J· September 2008

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Structure activity relationships of quinoline-containing c-Met inhibitors.
Pei-Pei Kung, Lee Funk, Jerry Meng, Gordon Alton, Ellen Padrique, Barbara Mroczkowski

Eur J Med Chem· June 2008

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Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma.
James G Christensen, Helen Y Zou, Maria E Arango, Qiuhua Li, Joseph H Lee, Barbara Mroczkowski

Mol Cancer Ther· December 2007

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Identification and characterization of a novel and functional murine Pin1 isoform.
Jeff X Zhu, Eleanor Dagostino, Paul A Rejto, Barbara Mroczkowski, Brion Murray

Biochem Biophys Res Commun· August 2007

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An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms.
Helen Y Zou, Qiuhua Li, Joseph H Lee, Maria E Arango, Scott R McDonnell, Barbara Mroczkowski

Cancer Res· May 2007

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