Publications by authors named "Barbra Sasu"

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Constitutive Turbodomains enhance expansion and antitumor activity of allogeneic BCMA CAR T cells in preclinical models.
Regina J Lin, Janette Sutton, Trevor Bentley, Diego A Vargas-Inchaustegui, Duy Nguyen, Barbra J Sasu

Sci Adv· August 2023

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Detection of chromosomal alteration after infusion of gene-edited allogeneic CAR T cells.
Barbra J Sasu, Gregory J Opiteck, Suhasni Gopalakrishnan, Vivek Kaimal, Tom Furmanak

Mol Ther· March 2023

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Allogeneic CAR T Cells Targeting DLL3 Are Efficacious and Safe in Preclinical Models of Small Cell Lung Cancer.
Yi Zhang, Silvia K Tacheva-Grigorova, Janette Sutton, Zea Melton, Yvonne S L Mak, Barbra J Sasu

Clin Cancer Res· March 2023

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Design and Validation of Inducible TurboCARs with Tunable Induction and Combinatorial Cytokine Signaling.
Regina J Lin, Andrew R Nager, Spencer Park, Janette Sutton, Cecilia Lay, Barbra J Sasu

Cancer Immunol Res· September 2022

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Preclinical Development and Evaluation of Allogeneic CAR T Cells Targeting CD70 for the Treatment of Renal Cell Carcinoma.
Siler H Panowski, Surabhi Srinivasan, Nguyen Tan, Silvia K Tacheva-Grigorova, Bryan Smith, Barbra J Sasu

Cancer Res· July 2022

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Allogeneic Anti-BCMA CAR T Cells Are Superior to Multiple Myeloma-derived CAR T Cells in Preclinical Studies and May Be Combined with Gamma Secretase Inhibitors.
Ana M Metelo, Agnieszka Jozwik, Le Anh Luong, Delaney Dominey-Foy, Charlotte Graham, Barbra Sasu

Cancer Res Commun· March 2022

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Direct control of CAR T cells through small molecule-regulated antibodies.
Spencer Park, Edward Pascua, Kevin C Lindquist, Christopher Kimberlin, Xiaodi Deng, Barbra Johnson Sasu

Nat Commun· January 2021

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Allogeneic FLT3 CAR T Cells with an Off-Switch Exhibit Potent Activity against AML and Can Be Depleted to Expedite Bone Marrow Recovery.
Cesar Sommer, Hsin-Yuan Cheng, Duy Nguyen, Danielle Dettling, Yik Andy Yeung, Barbra J Sasu

Mol Ther· October 2020

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An Optimized Full-Length FLT3/CD3 Bispecific Antibody Demonstrates Potent Anti-leukemia Activity and Reversible Hematological Toxicity.
Yik Andy Yeung, Veena Krishnamoorthy, Danielle Dettling, Cesar Sommer, Kris Poulsen, Barbra Sasu

Mol Ther· March 2020

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Preclinical Efficacy and Safety Comparison of CD3 Bispecific and ADC Modalities Targeting BCMA for the Treatment of Multiple Myeloma.
Siler H Panowski, Tracy C Kuo, Yi Zhang, Amy Chen, Tao Geng, Barbra J Sasu

Mol Cancer Ther· November 2019

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Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma.
Cesar Sommer, Bijan Boldajipour, Tracy C Kuo, Trevor Bentley, Janette Sutton, Barbra J Sasu

Mol Ther· June 2019

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A Versatile Safeguard for Chimeric Antigen Receptor T-Cell Immunotherapies.
Julien Valton, Valerie Guyot, Bijan Boldajipour, Cesar Sommer, Thomas Pertel, Barbra Johnson Sasu

Sci Rep· June 2018

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T Cell Redirecting Therapies for Cancer Treatment.
Barbra Sasu, Javier Chaparro-Riggers

Curr Cancer Drug Targets· September 2016

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Pharmacodynamic Model of Hepcidin Regulation of Iron Homeostasis in Cynomolgus Monkeys.
Wojciech Krzyzanski, Jim J Xiao, Barbra Sasu, Beth Hinkle, Juan Jose Perez-Ruixo

AAPS J· May 2016

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Romiplostim promotes platelet recovery in a mouse model of multicycle chemotherapy-induced thrombocytopenia.
Patricia L McElroy, Ping Wei, Keri Buck, Angus M Sinclair, Michael Eschenberg, Barbra Sasu

Exp Hematol· June 2015

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Serum hepcidin levels predict response to intravenous iron and darbepoetin in chemotherapy-associated anemia.
David P Steensma, Barbra J Sasu, Jeff A Sloan, Dianne K Tomita, Charles L Loprinzi

Blood· June 2015

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Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus.
Sara Gardenghi, Tom M Renaud, Alessandra Meloni, Carla Casu, Bart J Crielaard, Barbra J Sasu

Blood· February 2014

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A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates.
Keegan S Cooke, Beth Hinkle, Hossein Salimi-Moosavi, Ian Foltz, Chadwick King, Barbra J Sasu

Blood· October 2013

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Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT.
Sandra L Ross, Lynn Tran, Aaron Winters, Ki-Jeong Lee, Cherylene Plewa, Barbra J Sasu

Cell Metab· June 2012

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Serum hepcidin but not prohepcidin may be an effective marker for anemia of inflammation (AI).
Barbra J Sasu, Hongyan Li, Mark J Rose, Tara L Arvedson, George Doellgast

Blood Cells Mol Dis· October 2010

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Oxidative folding of hepcidin at acidic pH.
Jingwen Zhang, Stephanie Diamond, Tara Arvedson, Barbra J Sasu, Les P Miranda

Biopolymers· May 2010

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Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia.
Barbra J Sasu, Keegan S Cooke, Tara L Arvedson, Cherylene Plewa, Aaron R Ellison

Blood· April 2010

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Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS.
Hongyan Li, Mark J Rose, Linh Tran, Jingwen Zhang, Les P Miranda, Barbra J Sasu

J Pharmacol Toxicol Methods· September 2009

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Hepcidin revisited, disulfide connectivity, dynamics, and structure.
John B Jordan, Leszek Poppe, Mitsuru Haniu, Tara Arvedson, Rashid Syed, Barbra J Sasu

J Biol Chem· September 2009

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Comparison of epoetin alfa and darbepoetin alfa biological activity under different administration schedules in normal mice.
Barbra J Sasu, Cynthia Hartley, Henry Schultz, Patricia McElroy, Raheemuddin Khaja

Acta Haematol· May 2005

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