Publications by authors named "Barry Morgan"

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Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action.
Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, Maitriyee Mahanta, Matthew Banicki, Barry A Morgan

J Exp Med· November 2025

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Discovery, Characterization, and Structure of a Cell Active PAD2 Inhibitor Acting through a Novel Allosteric Mechanism.
Laura J Byrnes, Won Young Choi, Paul Balbo, Mary Ellen Banker, Jeanne Chang, Barry Morgan

ACS Chem Biol· October 2024

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PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery.
Huiyong Ma, James B Murray, Huadong Luo, Xuemin Cheng, Qiuxia Chen, Barry A Morgan

RSC Med Chem· November 2022

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Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT).
Yun Ding, Svetlana Belyanskaya, Jennifer L DeLorey, Jeffrey A Messer, G Joseph Franklin, Barry A Morgan

Bioorg Med Chem· July 2021

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Employing Photocatalysis for the Design and Preparation of DNA-Encoded Libraries: A Case Study.
Dominik K Kölmel, Hongyao Zhu, Mark E Flanagan, Sylvie K Sakata, Anthony R Harris, Barry A Morgan

Chem Rec· April 2021

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Characterization of Specific -α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Pei-Pei Kung, Patrick Bingham, Benjamin J Burke, Qiuxia Chen, Xuemin Cheng, Barry A Morgan

ACS Med Chem Lett· June 2020

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An investigation of symptoms predating CFS onset.
Meredyth Evans, Morgan Barry, Young Im, Abigail Brown, Leonard A Jason

J Prev Interv Community· January 2016

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Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT).
Yun Ding, Heather O'Keefe, Jennifer L DeLorey, David I Israel, Jeffrey A Messer, Barry A Morgan

ACS Med Chem Lett· August 2015

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Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library.
Hongfeng Deng, Jingye Zhou, Flora S Sundersingh, Jennifer Summerfield, Don Somers, Barry A Morgan

ACS Med Chem Lett· August 2015

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Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists.
Christopher S Kollmann, Xiaopeng Bai, Ching-Hsuan Tsai, Hongfang Yang, Kenneth E Lind, Barry A Morgan

Bioorg Med Chem· April 2014

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In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor.
Patricia L Podolin, Brian J Bolognese, Joseph F Foley, Edward Long, Brian Peck, Barry A Morgan

Prostaglandins Other Lipid Mediat· January 2014

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Discovery of Clinical Candidate GSK1842799 As a Selective S1P1 Receptor Agonist (Prodrug) for Multiple Sclerosis.
Hongfeng Deng, Sylvie G Bernier, Elisabeth Doyle, Jeanine Lorusso, Barry A Morgan

ACS Med Chem Lett· October 2013

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Metabolites of PPI-2458, a selective, irreversible inhibitor of methionine aminopeptidase-2: structure determination and in vivo activity.
Christopher C Arico-Muendel, Bruce Belanger, Dennis Benjamin, Heather S Blanchette, Teresa M Caiazzo, Barry A Morgan

Drug Metab Dispos· April 2013

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Orally active fumagillin analogues: transformations of a reactive warhead in the gastric environment.
Christopher C Arico-Muendel, Heather Blanchette, Dennis R Benjamin, Teresa M Caiazzo, Paolo A Centrella, Barry A Morgan

ACS Med Chem Lett· April 2013

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Exploring amino acids derivatives as potent, selective, and direct agonists of sphingosine-1-phosphate receptor subtype-1.
Ghotas Evindar, Hongfeng Deng, Sylvie G Bernier, Elisabeth Doyle, Jeanine Lorusso, Barry A Morgan

Bioorg Med Chem Lett· January 2013

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Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT).
Hongfeng Deng, Heather O'Keefe, Christopher P Davie, Kenneth E Lind, Raksha A Acharya, Barry A Morgan

J Med Chem· August 2012

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Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists.
Ghotas Evindar, Sylvie G Bernier, Elisabeth Doyle, Malcolm J Kavarana, Alexander L Satz, Barry A Morgan

Bioorg Med Chem Lett· April 2010

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Carbamate analogues of fumagillin as potent, targeted inhibitors of methionine aminopeptidase-2.
Christopher C Arico-Muendel, Dennis R Benjamin, Teresa M Caiazzo, Paolo A Centrella, Brooke D Contonio, Barry A Morgan

J Med Chem· December 2009

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Antiparasitic activities of novel, orally available fumagillin analogs.
Christopher Arico-Muendel, Paolo A Centrella, Brooke D Contonio, Barry A Morgan, Gary O'Donovan

Bioorg Med Chem Lett· September 2009

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Design, synthesis and selection of DNA-encoded small-molecule libraries.
Matthew A Clark, Raksha A Acharya, Christopher C Arico-Muendel, Svetlana L Belyanskaya, Dennis R Benjamin, Barry A Morgan

Nat Chem Biol· September 2009

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Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists.
Ghotas Evindar, Alexander L Satz, Sylvie G Bernier, Malcolm J Kavarana, Elisabeth Doyle, Barry A Morgan

Bioorg Med Chem Lett· April 2009

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Tailgut cysts: report of two cases.
Eleanor Au, Oliver Anderson, Barry Morgan, Lida Alarcon, Mark L George

Int J Colorectal Dis· March 2009

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Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists.
Ghotas Evindar, Sylvie G Bernier, Malcolm J Kavarana, Elisabeth Doyle, Jeanine Lorusso, Barry A Morgan

Bioorg Med Chem Lett· January 2009

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Not only coughs and sneezes.
Rachel L O'Connell, Amjid A Riaz, Barry Morgan, Elliott Smock, Johnathan G Hubbard

Lancet· November 2008

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Anterior canal benign paroxysmal positional vertigo: an underappreciated entity.
Lance E Jackson, Barry Morgan, Jeffrey C Fletcher, Wesley W O Krueger

Otol Neurotol· February 2007

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