Publications by authors named "Bart Stoops"

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VH antibody loop guides design of a synthetic macrocyclic peptide that potently blocks influenza virus membrane fusion.
Rameshwar U Kadam, Jarek Juraszek, Boerries Brandenburg, Divita Garg, Xueyong Zhu, Bart Stoops

Npj Viruses· December 2025

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The role of cytochrome bc inhibitors in future tuberculosis treatment regimens.
Clara Aguilar-Pérez, Anne J Lenaerts, Cristina Villellas, Jerome Guillemont, John Dallow, Bart Stoops

Nat Commun· October 2025

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Targeting de novo purine biosynthesis for tuberculosis treatment.
Dirk A Lamprecht, Richard J Wall, Annelies Leemans, Barry Truebody, Joke Sprangers, Bart Stoops

Nature· August 2025

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Discovery of a non-nucleoside inhibitor that binds to a novel site in the palm domain of the respiratory syncytial virus RNA-dependent RNA polymerase.
Jay H Kalin, Yanting Yin, Minh T Tran, Madison Piassek, Amy Fung, Bart Stoops

J Virol· July 2025

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DNA-Encoded Library Screen Identifies Novel Series of Respiratory Syncytial Virus Polymerase Inhibitors.
Sean M Carney, Sandrine Grosse, Yanting Yin, Minh T Tran, Jay H Kalin, Bart Stoops

J Med Chem· March 2025

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The antiviral JNJ-A07 significantly reduces dengue virus transmission by mosquitoes when delivered via blood-feeding.
Ana L Rosales-Rosas, Sara Goossens, Winston Chiu, Atreyee Majumder, Alina Soto, Bart Stoops

Sci Adv· November 2024

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Structure-Activity Relationship of Oxacyclo- and Triazolo-Containing Respiratory Syncytial Virus Polymerase Inhibitors.
Minh T Tran, Sandrine Grosse, Rodrigo J Carbajo, Edgar Jacoby, Yanting Yin, Bart Stoops

ACS Med Chem Lett· September 2024

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Discovery of -Dimethyl-hydroxymethylpyridine Derivatives as Potent Non-nucleoside RSV Polymerase Inhibitors.
Sandrine Grosse, Ludwig Cooymans, Werner Embrechts, David McGowan, Edgar Jacoby, Bart Stoops

J Med Chem· August 2024

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Spiro-Azetidine Oxindoles as Long-Acting Injectables for Pre-Exposure Prophylaxis against Respiratory Syncytial Virus Infections.
Bart Kesteleyn, Florence Herschke, Nicolas Darville, Bart Stoops, Tom Jacobs

J Med Chem· July 2024

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Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor.
Bart Kesteleyn, Jean-François Bonfanti, Dorothée Bardiot, Benoît De Boeck, Olivia Goethals, Bart Stoops

J Med Chem· March 2024

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Di-fluoro azepane HBV capsid assembly modulators.
Lindsey G DeRatt, Bart Stoops, Paul Shaffer, Angela M Lam, Christine Espiritu

Bioorg Med Chem Lett· August 2023

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Discovery of Acyl-Indole Derivatives as Pan-Serotype Dengue Virus NS4B Inhibitors.
Bart Kesteleyn, Dorothée Bardiot, Jean-François Bonfanti, Benoît De Boeck, Olivia Goethals, Bart Stoops

J Med Chem· July 2023

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Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
Olivia Goethals, Suzanne J F Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Bart Stoops

Nature· March 2023

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From Oxetane to Thietane: Extending the Antiviral Spectrum of 2'-Spirocyclic Uridines by Substituting Oxygen with Sulfur.
Sandrine Grosse, Abdellah Tahri, Pierre Raboisson, Yannis Houpis, Bart Stoops

ACS Med Chem Lett· December 2022

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Diazepinone HBV capsid assembly modulators.
Scott D Kuduk, Lindsey G DeRatt, Bart Stoops, Paul Shaffer, Angela M Lam

Bioorg Med Chem Lett· September 2022

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Oxadiazepinone HBV capsid assembly modulators.
Scott D Kuduk, Bart Stoops, Angela M Lam, Christine Espiritu, Robert Vogel

Bioorg Med Chem Lett· November 2021

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Publisher Correction: A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Suzanne J F Kaptein, Olivia Goethals, Dominik Kiemel, Arnaud Marchand, Bart Kesteleyn, Bart Stoops

Nature· November 2021

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A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Suzanne J F Kaptein, Olivia Goethals, Dominik Kiemel, Arnaud Marchand, Bart Kesteleyn, Bart Stoops

Nature· October 2021

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Identification of a new class of HBV capsid assembly modulator.
Scott D Kuduk, Bart Stoops, Richard Alexander, Angela M Lam, Christine Espiritu

Bioorg Med Chem Lett· May 2021

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Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region.
David C McGowan, Wendy Balemans, Werner Embrechts, Magali Motte, Jeremy R Keown, Bart Stoops

J Med Chem· November 2019

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A small-molecule fusion inhibitor of influenza virus is orally active in mice.
Maria J P van Dongen, Rameshwar U Kadam, Jarek Juraszek, Edward Lawson, Boerries Brandenburg, Bart Stoops

Science· March 2019

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Design and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists.
David C McGowan, Florence Herschke, Mourad D Khamlichi, Mari Luz Rosauro, Sara M Pérez Benedicto, Bart Stoops

Bioorg Med Chem Lett· October 2018

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Synthesis and Evaluation of N-Phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators Inhibiting Hepatitis B Virus (HBV).
Koen Vandyck, Geert Rombouts, Bart Stoops, Abdellah Tahri, Ann Vos

J Med Chem· July 2018

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2,4-Diaminoquinazolines as Dual Toll-like Receptor (TLR) 7/8 Modulators for the Treatment of Hepatitis B Virus.
Werner Embrechts, Florence Herschke, Frederik Pauwels, Bart Stoops, Stefaan Last

J Med Chem· July 2018

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Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists.
Serge Pieters, David McGowan, Florence Herschke, Frederik Pauwels, Bart Stoops

Bioorg Med Chem Lett· February 2018

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