Publications by authors named "Bryan Howie"

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Antigen-driven expansion of public clonal T-cell populations in inflammatory bowel diseases.
Mitchell Pesesky, Ramit Bharanikumar, Lionel Le Bourhis, Hesham ElAbd, Elisa Rosati, Bryan Howie

J Crohns Colitis· July 2025

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T and B cell responses against Epstein-Barr virus in primary sclerosing cholangitis.
Hesham ElAbd, Mitchell Pesesky, Gabriel Innocenti, Brian K Chung, Aya K H Mahdy, Bryan Howie

Nat Med· July 2025

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Vaccine-induced T cell responses correlate with reduced risk of severe COVID-19 in a placebo-controlled efficacy trial.
Nina Hertoghs, Sanne Roels, Matthias Brückner, Jerald Sadoff, Barbara L Banbury, Bryan Howie

EBioMedicine· July 2025

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Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels.
Thomas M Snyder, Rachel M Gittelman, Mark Klinger, Damon H May, Edward J Osborne, Bryan Howie

Front Immunol· May 2025

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A large-scale database of T-cell receptor beta sequences and binding associations from natural and synthetic exposure to SARS-CoV-2.
Sean Nolan, Marissa Vignali, Mark Klinger, Jennifer N Dines, Ian M Kaplan, Bryan Howie

Front Immunol· May 2025

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Multimodal, broadly neutralizing antibodies against SARS-CoV-2 identified by high-throughput native pairing of BCRs from bulk B cells.
Gladys J Keitany, Benjamin E R Rubin, Meghan E Garrett, Andrea Musa, Jeff Tracy, Bryan Howie

Cell Chem Biol· November 2023

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Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium.
Heather M Callaway, Kathryn M Hastie, Sharon L Schendel, Haoyang Li, Xiaoying Yu, Bryan Howie

Cell Rep· January 2023

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Analytical evaluation of the clonoSEQ Assay for establishing measurable (minimal) residual disease in acute lymphoblastic leukemia, chronic lymphocytic leukemia, and multiple myeloma.
Travers Ching, Megan E Duncan, Tera Newman-Eerkes, Mollie M E McWhorter, Jeffrey M Tracy, Bryan Howie

BMC Cancer· June 2020

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Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer.
Sanja Stevanović, Anna Pasetto, Sarah R Helman, Jared J Gartner, Todd D Prickett, Bryan Howie

Science· April 2017

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Tumor- and Neoantigen-Reactive T-cell Receptors Can Be Identified Based on Their Frequency in Fresh Tumor.
Anna Pasetto, Alena Gros, Paul F Robbins, Drew C Deniger, Todd D Prickett, Bryan Howie

Cancer Immunol Res· September 2016

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Estimating the Ages of Selection Signals from Different Epochs in Human History.
Shigeki Nakagome, Gorka Alkorta-Aranburu, Roberto Amato, Bryan Howie, Benjamin M Peter

Mol Biol Evol· March 2016

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Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel.
Jie Huang, Bryan Howie, Shane McCarthy, Yasin Memari, Klaudia Walter

Nat Commun· September 2015

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High-throughput pairing of T cell receptor α and β sequences.
Bryan Howie, Anna M Sherwood, Ashley D Berkebile, Jan Berka, Ryan O Emerson

Sci Transl Med· August 2015

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Detection of minimal residual disease in B lymphoblastic leukemia by high-throughput sequencing of IGH.
David Wu, Ryan O Emerson, Anna Sherwood, Mignon L Loh, Anne Angiolillo, Bryan Howie

Clin Cancer Res· September 2014

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A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
Lara M Mangravite, Barbara E Engelhardt, Marisa W Medina, Joshua D Smith, Christopher D Brown, Bryan Howie

Nature· October 2013

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Haplotype estimation using sequencing reads.
Olivier Delaneau, Bryan Howie, Anthony J Cox, Jean-François Zagury, Jonathan Marchini

Am J Hum Genet· October 2013

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The origin, evolution, and functional impact of short insertion-deletion variants identified in 179 human genomes.
Stephen B Montgomery, David L Goode, Erika Kvikstad, Cornelis A Albers, Zhengdong D Zhang, Bryan Howie

Genome Res· May 2013

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1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.
Jie Huang, David Ellinghaus, Andre Franke, Bryan Howie, Yun Li

Eur J Hum Genet· July 2012

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Fast and accurate genotype imputation in genome-wide association studies through pre-phasing.
Bryan Howie, Christian Fuchsberger, Matthew Stephens, Jonathan Marchini, Gonçalo R Abecasis

Nat Genet· July 2012

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Genotype imputation with thousands of genomes.
Bryan Howie, Jonathan Marchini, Matthew Stephens

G3 (Bethesda)· November 2011

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Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.
Ian P M Tomlinson, Luis G Carvajal-Carmona, Sara E Dobbins, Albert Tenesa, Angela M Jones, Bryan Howie

PLoS Genet· June 2011

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Genotype imputation for genome-wide association studies.
Jonathan Marchini, Bryan Howie

Nat Rev Genet· July 2010

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Genome-wide and fine-resolution association analysis of malaria in West Africa.
Muminatou Jallow, Yik Ying Teo, Kerrin S Small, Kirk A Rockett, Panos Deloukas, Bryan Howie

Nat Genet· June 2009

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A flexible and accurate genotype imputation method for the next generation of genome-wide association studies.
Bryan N Howie, Peter Donnelly, Jonathan Marchini

PLoS Genet· June 2009

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Comparing algorithms for genotype imputation.
Jonathan Marchini, Bryan Howie

Am J Hum Genet· October 2008

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