Publications by authors named "Christine Brideau"

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Discovery of novel P2Y14 agonist and antagonist using conventional and nonconventional methods.
Martine Hamel, Martin Henault, Huda Hyjazie, Nicolas Morin, Christopher Bayly, Christine Brideau

J Biomol Screen· October 2011

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Trisubstituted ureas as potent and selective mPGES-1 inhibitors.
Jean-François Chiasson, Louise Boulet, Christine Brideau, Anh Chau, David Claveau

Bioorg Med Chem Lett· March 2011

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Biarylimidazoles as inhibitors of microsomal prostaglandin E2 synthase-1.
Tom Y H Wu, Hélène Juteau, Yves Ducharme, Richard W Friesen, Sébastien Guiral, Christine Brideau

Bioorg Med Chem Lett· December 2010

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The discovery of setileuton, a potent and selective 5-lipoxygenase inhibitor.
Yves Ducharme, Marc Blouin, Christine Brideau, Anne Châteauneuf, Yves Gareau

ACS Med Chem Lett· July 2010

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Discovery of disubstituted phenanthrene imidazoles as potent, selective and orally active mPGES-1 inhibitors.
André Giroux, Louise Boulet, Christine Brideau, Anh Chau, David Claveau

Bioorg Med Chem Lett· October 2009

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Substituted 2,2-bisaryl-bicycloheptanes as novel and potent inhibitors of 5-lipoxygenase activating protein.
Dwight Macdonald, Christine Brideau, Chi Chung Chan, Jean-Pierre Falgueyret, Richard Frenette

Bioorg Med Chem Lett· March 2008

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Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors.
Bernard Côté, Louise Boulet, Christine Brideau, David Claveau, Diane Ethier

Bioorg Med Chem Lett· December 2007

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Pharmacological characterization of a selective COX-2 inhibitor MF-tricyclic, [3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone], in multiple preclinical species.
Steven E Rowland, Patsy Clark, Robert Gordon, Anne K Mullen, Jocelyne Guay, Christine Brideau

Eur J Pharmacol· April 2007

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Identification of an indole series of prostaglandin D2 receptor antagonists.
Claudio F Sturino, Nicolas Lachance, Michael Boyd, Carl Berthelette, Marc Labelle, Christine Brideau

Bioorg Med Chem Lett· June 2006

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Substituted coumarins as potent 5-lipoxygenase inhibitors.
Erich L Grimm, Christine Brideau, Nathalie Chauret, Chi-Chung Chan, Daniel Delorme

Bioorg Med Chem Lett· May 2006

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An automated multistep high-throughput screening assay for the identification of lead inhibitors of the inducible enzyme mPGES-1.
Frédéric Massé, Sébastien Guiral, Louis-Jacques Fortin, Elizabeth Cauchon, Diane Ethier, Christine Brideau

J Biomol Screen· September 2005

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In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in cats with lipopolysaccharide-induced pyrexia.
Margaret E McCann, Eric L Rickes, Donald F Hora, Paul K Cunningham, Donghui Zhang, Christine Brideau

Am J Vet Res· July 2005

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In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in dogs with experimentally induced synovitis.
Margaret E McCann, Donald R Andersen, Donghui Zhang, Christine Brideau, W Cameron Black

Am J Vet Res· April 2004

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Statistical and graphical methods for quality control determination of high-throughput screening data.
Bert Gunter, Christine Brideau, Bill Pikounis, Andy Liaw

J Biomol Screen· December 2003

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Improved statistical methods for hit selection in high-throughput screening.
Christine Brideau, Bert Gunter, Bill Pikounis, Andy Liaw

J Biomol Screen· December 2003

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3,4-Diaryl-5-hydroxyfuranones: highly selective inhibitors of cyclooxygenase-2 with aqueous solubility.
W Cameron Black, Christine Brideau, Chi Chung Chan, Stella Charleson, Wanda Cromlish

Bioorg Med Chem Lett· March 2003

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Pyridazinones as selective cyclooxygenase-2 inhibitors.
Chun Sing Li, Christine Brideau, Chi Chung Chan, Chantal Savoie, David Claveau

Bioorg Med Chem Lett· February 2003

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Substituted aminopyridines as potent and selective phosphodiesterase-4 inhibitors.
Bernard Côté, Richard Frenette, Sylvie Prescott, Marc Blouin, Christine Brideau

Bioorg Med Chem Lett· February 2003

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Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile.
Yves Leblanc, Patrick Roy, Zhaoyin Wang, Chun Sing Li, Nathalie Chauret, Christine Brideau

Bioorg Med Chem Lett· November 2002

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Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters.
Richard Frenette, Marc Blouin, Christine Brideau, Nathalie Chauret, Yves Ducharme

Bioorg Med Chem Lett· October 2002

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Discovery of L-791,943: a potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor.
Daniel Guay, Pierre Hamel, Marc Blouin, Christine Brideau, Chi Chung Chan

Bioorg Med Chem Lett· June 2002

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