Publications by authors named "Christopher T Jones"

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Selective thyroid hormone receptor β agonists with oxadiazolone acid isosteres.
Thorsten A Kirschberg, Christopher T Jones, Yingzi Xu, Martijn Fenaux, Randall L Halcomb

Bioorg Med Chem Lett· November 2020

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A Phenotype-Genotype Codon Model for Detecting Adaptive Evolution.
Christopher T Jones, Noor Youssef, Edward Susko, Joseph P Bielawski

Syst Biol· July 2020

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The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease.
F Anthony Romero, Christopher T Jones, Yingzi Xu, Martijn Fenaux, Randall L Halcomb

J Med Chem· May 2020

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The Temporal Neurogenesis Patterning of Spinal p3-V3 Interneurons into Divergent Subpopulation Assemblies.
Dylan Deska-Gauthier, Joanna Borowska-Fielding, Christopher T Jones, Ying Zhang

J Neurosci· February 2020

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Looking for Darwin in Genomic Sequences: Validity and Success Depends on the Relationship Between Model and Data.
Christopher T Jones, Edward Susko, Joseph P Bielawski

Methods Mol Biol· January 2020

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A first-in-human, randomized, double-blind, placebo-controlled, single and multiple ascending oral dose study to assess the safety, tolerability, and pharmacokinetics of BZF961 with and without ritonavir in healthy adult volunteers.
Stephen Youngberg, Erin Brandt, Avantika Barve, Surendra Machineni, Christopher T Jones, Catherine L Jones

J Drug Assess· October 2018

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The Safety and Antiviral Activity of BZF961 with or without Ritonavir in Patients Infected with Hepatitis C Virus: A Randomized, Multicenter Trial.
Eric Lawitz, Mohamed Bidair, Thomas Marbury, Christopher T Jones, Avantika Barve, Catherine L Jones

Clin Ther· September 2018

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Phenomenological Load on Model Parameters Can Lead to False Biological Conclusions.
Christopher T Jones, Noor Youssef, Edward Susko, Joseph P Bielawski

Mol Biol Evol· June 2018

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Shifting Balance on a Static Mutation-Selection Landscape: A Novel Scenario of Positive Selection.
Christopher T Jones, Noor Youssef, Edward Susko, Joseph P Bielawski

Mol Biol Evol· February 2017

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Preclinical and Clinical Resistance Profile of EDP-239, a Novel Hepatitis C Virus NS5A Inhibitor.
Christopher M Owens, Bradley B Brasher, Alex Polemeropoulos, Michael H J Rhodin, Nicole McAllister, Christopher T Jones

Antimicrob Agents Chemother· October 2016

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The N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production.
Margaret A Scull, William M Schneider, Brenna R Flatley, Robert Hayden, Canny Fung, Christopher T Jones

PLoS Pathog· November 2015

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Sim1 is required for the migration and axonal projections of V3 interneurons in the developing mouse spinal cord.
Jake Blacklaws, Dylan Deska-Gauthier, Christopher T Jones, Yanina L Petracca, Mingwei Liu

Dev Neurobiol· September 2015

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Corrigendum: A diverse range of gene products are effectors of the type I interferon antiviral response.
John W Schoggins, Sam J Wilson, Maryline Panis, Mary Y Murphy, Christopher T Jones

Nature· September 2015

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Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.
David Barnes-Seeman, Carri Boiselle, Christina Capacci-Daniel, Rajiv Chopra, Keith Hoffmaster, Christopher T Jones

Bioorg Med Chem Lett· August 2014

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Functional subpopulations of V3 interneurons in the mature mouse spinal cord.
Joanna Borowska, Christopher T Jones, Han Zhang, Jake Blacklaws, Martyn Goulding

J Neurosci· November 2013

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A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans.
John Lok Man Law, Chao Chen, Jason Wong, Darren Hockman, Deanna M Santer, Christopher T Jones

PLoS One· September 2013

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Different requirements for scavenger receptor class B type I in hepatitis C virus cell-free versus cell-to-cell transmission.
Maria Teresa Catanese, Joana Loureiro, Christopher T Jones, Marcus Dorner, Thomas von Hahn

J Virol· August 2013

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Development of a multiplex phenotypic cell-based high throughput screening assay to identify novel hepatitis C virus antivirals.
Hee-Young Kim, Xiaolan Li, Christopher T Jones, Charles M Rice, Jean-Michel Garcia

Antiviral Res· July 2013

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A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo.
Philip Meuleman, Maria Teresa Catanese, Lieven Verhoye, Isabelle Desombere, Ali Farhoudi, Christopher T Jones

Hepatology· February 2012

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Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures.
Svetlana Marukian, Linda Andrus, Timothy P Sheahan, Christopher T Jones, Edgar D Charles

Hepatology· December 2011

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Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells.
Linda Andrus, Svetlana Marukian, Christopher T Jones, Maria Teresa Catanese, Timothy P Sheahan

Hepatology· December 2011

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A genetically humanized mouse model for hepatitis C virus infection.
Marcus Dorner, Joshua A Horwitz, Justin B Robbins, Walter T Barry, Qian Feng, Christopher T Jones

Nature· June 2011

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A diverse range of gene products are effectors of the type I interferon antiviral response.
John W Schoggins, Sam J Wilson, Maryline Panis, Mary Y Murphy, Christopher T Jones

Nature· April 2011

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Advances and challenges in studying hepatitis C virus in its native environment.
Timothy Sheahan, Christopher T Jones, Alexander Ploss

Expert Rev Gastroenterol Hepatol· October 2010

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Identification of a dominant negative inhibitor of human zinc finger antiviral protein reveals a functional endogenous pool and critical homotypic interactions.
Lok Man J Law, Owen R Albin, John-William N Carroll, Christopher T Jones, Charles M Rice

J Virol· May 2010

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