Publications by authors named "Craig Fairchild"

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Pharmacology of smac mimetics; chemotype differentiation based on physical association with caspase regulators and cellular transport.
Randy L Talbott, Robert M Borzilleri, Charu Chaudhry, Joseph Fargnoli, Henry Shen, Craig Fairchild

Exp Cell Res· November 2015

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Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression.
Ryan Lenhart, Stefan Kirov, Heshani Desilva, Jian Cao, Ming Lei, Craig Fairchild

Mol Cancer Ther· October 2015

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IRS2 copy number gain, KRAS and BRAF mutation status as predictive biomarkers for response to the IGF-1R/IR inhibitor BMS-754807 in colorectal cancer cell lines.
Fei Huang, Han Chang, Ann Greer, Stephen Hillerman, Karen A Reeves, Craig Fairchild

Mol Cancer Ther· February 2015

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Carcinogenicity risk assessment supports the chronic safety of dapagliflozin, an inhibitor of sodium-glucose co-transporter 2, in the treatment of type 2 diabetes mellitus.
Timothy P Reilly, Michael J Graziano, Evan B Janovitz, Thomas E Dorr, Craig Fairchild

Diabetes Ther· June 2014

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Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: observation of extensive dynamics in an enzyme/inhibitor complex.
Soong-Hoon Kim, Keith L Constantine, Gerald J Duke, Valentina Goldfarb, John T Hunt, Craig R Fairchild

Bioorg Med Chem Lett· July 2013

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Bromophycoic acids: bioactive natural products from a Fijian red alga Callophycus sp.
Margaret E Teasdale, Tonya L Shearer, Sebastian Engel, Troy S Alexander, Craig R Fairchild

J Org Chem· September 2012

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Antitumor and antiangiogenic activities of BMS-690514, an inhibitor of human EGF and VEGF receptor kinase families.
Tai W Wong, Francis Y Lee, Stuart Emanuel, Craig Fairchild, Joseph Fargnoli

Clin Cancer Res· June 2011

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Structure and biological evaluation of novel cytotoxic sterol glycosides from the marine red alga Peyssonnelia sp.
An-Shen Lin, Sebastian Engel, Benjamin A Smith, Craig R Fairchild, William Aalbersberg

Bioorg Med Chem· December 2010

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Unusual antimalarial meroditerpenes from tropical red macroalgae.
E Paige Stout, Jacques Prudhomme, Karine Le Roch, Craig R Fairchild, Scott G Franzblau

Bioorg Med Chem Lett· October 2010

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Bioactive bromophycolides R-U from the Fijian red alga Callophycus serratus.
An-Shen Lin, E Paige Stout, Jacques Prudhomme, Karine Le Roch, Craig R Fairchild

J Nat Prod· February 2010

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Ecological leads for natural product discovery: Novel sesquiterpene hydroquinones from the red macroalga Peyssonnelia sp.
Amy L Lane, Laurlynn Mular, Elizabeth J Drenkard, Tonya L Shearer, Sebastian Engel, Craig R Fairchild

Tetrahedron· January 2010

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Antimalarial bromophycolides J-Q from the Fijian red alga Callophycus serratus.
Amy L Lane, E Paige Stout, An-Shen Lin, Jacques Prudhomme, Karine Le Roch, Craig R Fairchild

J Org Chem· April 2009

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Preclinical efficacy spectrum and pharmacokinetics of ixabepilone.
Francis Y F Lee, Richard Smykla, Kathy Johnston, Krista Menard, Kelly McGlinchey, Craig R Fairchild

Cancer Chemother Pharmacol· January 2009

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Antibacterial neurymenolides from the Fijian red alga Neurymenia fraxinifolia.
E Paige Stout, Adam P Hasemeyer, Amy L Lane, Theresa M Davenport, Sebastian Engel, Craig R Fairchild

Org Lett· January 2009

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BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells.
Beate C Litzenburger, Hyun-Jung Kim, Isere Kuiatse, Joan M Carboni, Ricardo M Attar, Craig R Fairchild

Clin Cancer Res· January 2009

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Discovery of anticancer agents of diverse natural origin.
A Douglas Kinghorn, Esperanza J Carcache de Blanco, Hee-Byung Chai, Jimmy Orjala, Norman R Farnsworth, Craig R Fairchild

Pure Appl Chem· January 2009

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Preclinical discovery of ixabepilone, a highly active antineoplastic agent.
Francis Y F Lee, Robert Borzilleri, Craig R Fairchild, Amrita Kamath, Richard Smykla

Cancer Chemother Pharmacol· December 2008

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Synergistic antitumor activity of ixabepilone (BMS-247550) plus bevacizumab in multiple in vivo tumor models.
Francis Y F Lee, Kelly L Covello, Stephen Castaneda, Donald R Hawken, David Kan, Craig R Fairchild

Clin Cancer Res· December 2008

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Antineoplastic unsaturated fatty acids from Fijian macroalgae.
Ren-Wang Jiang, Mark E Hay, Craig R Fairchild, Jacques Prudhomme, Karine Le Roch

Phytochemistry· October 2008

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Structures and absolute configurations of sulfate-conjugated triterpenoids including an antifungal chemical defense of the green macroalga Tydemania expeditionis.
Ren-Wang Jiang, Amy L Lane, Lauren Mylacraine, Kenneth I Hardcastle, Craig R Fairchild

J Nat Prod· September 2008

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Cytotoxic xanthones from Psorospermum molluscum from the Madagascar rain forest.
John E Leet, Xiaohong Liu, Dieter M Drexler, Joseph L Cantone, Stella Huang, Craig R Fairchild

J Nat Prod· March 2008

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Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus.
Amy L Lane, Elizabeth P Stout, Mark E Hay, Anne C Prusak, Kenneth Hardcastle, Craig R Fairchild

J Org Chem· September 2007

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Marmycins A and B, cytotoxic pentacyclic C-glycosides from a marine sediment-derived actinomycete related to the genus Streptomyces.
Glenroy D A Martin, Lik T Tan, Paul R Jensen, Rosalba Encarnacion Dimayuga, Craig R Fairchild

J Nat Prod· September 2007

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Alvaradoins E-N, antitumor and cytotoxic anthracenone C-glycosides from the leaves of Alvaradoa haitiensis.
Sharnelle S Phifer, Dongho Lee, Eun-Kyoung Seo, Nam-Cheol Kim, Tyler N Graf, Craig R Fairchild

J Nat Prod· June 2007

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Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection.
Fei Huang, Karen Reeves, Xia Han, Craig Fairchild, Suso Platero

Cancer Res· March 2007

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