Publications by authors named "Daniel N Bolon"

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Cooperativity and Communication between the Active Sites of the Dimeric SARS-CoV-2 Main Protease.
Sarah N Zvornicanin, Ala M Shaqra, Julia Flynn, Lauren E Intravaia, Heidi Carias Martinez, Daniel N Bolon

bioRxiv· July 2025

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Molecular mechanisms of drug resistance and compensation in SARS-CoV-2 main protease: the interplay between E166 and L50.
Sarah N Zvornicanin, Ala M Shaqra, Julia Flynn, Heidi Carias Martinez, Weiping Jia, Daniel N Bolon

mBio· May 2025

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Comprehensive fitness maps of Hsp90 show widespread environmental dependence.
Julia M Flynn, Ammeret Rossouw, Pamela Cote-Hammarlof, Inês Fragata, David Mavor, Daniel Na Bolon

Elife· March 2020

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Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance.
David Mavor, Kyle A Barlow, Daniel Asarnow, Yuliya Birman, Derek Britain, Daniel N Bolon

Biol Open· July 2018

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Evolutionary mechanisms studied through protein fitness landscapes.
Aneth S Canale, Pamela A Cote-Hammarlof, Julia M Flynn, Daniel Na Bolon

Curr Opin Struct Biol· February 2018

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CRISPR-Cas9-mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy.
Leyuan Ma, Jeffrey I Boucher, Janet Paulsen, Sebastian Matuszewski, Christopher A Eide, Daniel N Bolon

Proc Natl Acad Sci U S A· October 2017

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A synthetic biology approach to probing nucleosome symmetry.
Yuichi Ichikawa, Caitlin F Connelly, Alon Appleboim, Thomas Cr Miller, Hadas Jacobi, Daniel Na Bolon

Elife· September 2017

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The Combined Effect of Oseltamivir and Favipiravir on Influenza A Virus Evolution.
Louise Ormond, Ping Liu, Sebastian Matuszewski, Nicholas Renzette, Claudia Bank, Daniel N Bolon

Genome Biol Evol· July 2017

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The diverse roles of Hsp90 and where to find them.
Patricija Van Oosten-Hawle, Daniel N A Bolon, Paul LaPointe

Nat Struct Mol Biol· January 2017

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Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase.
Kristina L Prachanronarong, Ayşegül Özen, Kelly M Thayer, L Safak Yilmaz, Konstantin B Zeldovich, Daniel N Bolon

J Chem Theory Comput· December 2016

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An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy.
Claudia Bank, Nicholas Renzette, Ping Liu, Sebastian Matuszewski, Hyunjin Shim, Daniel N A Bolon

Evolution· November 2016

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Quantifying and understanding the fitness effects of protein mutations: Laboratory versus nature.
Jeffrey I Boucher, Daniel N A Bolon, Dan S Tawfik

Protein Sci· July 2016

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Editorial.
Daniel N A Bolon, David Baker, Dan S Tawfik

Protein Sci· July 2016

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Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting.
David Mavor, Kyle Barlow, Samuel Thompson, Benjamin A Barad, Alain R Bonny, Daniel N Bolon

Elife· April 2016

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Mechanistic Asymmetry in Hsp90 Dimers.
Julia M Flynn, Parul Mishra, Daniel N A Bolon

J Mol Biol· September 2015

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Positive Selection Drives Preferred Segment Combinations during Influenza Virus Reassortment.
Konstantin B Zeldovich, Ping Liu, Nicholas Renzette, Matthieu Foll, Serena T Pham, Daniel N Bolon

Mol Biol Evol· June 2015

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A systematic survey of an intragenic epistatic landscape.
Claudia Bank, Ryan T Hietpas, Jeffrey D Jensen, Daniel N A Bolon

Mol Biol Evol· January 2015

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Viewing protein fitness landscapes through a next-gen lens.
Jeffrey I Boucher, Pamela Cote, Julia Flynn, Li Jiang, Aneth Laban, Daniel N A Bolon

Genetics· October 2014

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Systematic exploration of ubiquitin sequence, E1 activation efficiency, and experimental fitness in yeast.
Benjamin P Roscoe, Daniel N A Bolon

J Mol Biol· July 2014

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Alanine scan of core positions in ubiquitin reveals links between dynamics, stability, and function.
Shirley Y Lee, Lester Pullen, Daniel J Virgil, Carlos A Castañeda, Dulith Abeykoon, Daniel N A Bolon

J Mol Biol· April 2014

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A bayesian MCMC approach to assess the complete distribution of fitness effects of new mutations: uncovering the potential for adaptive walks in challenging environments.
Claudia Bank, Ryan T Hietpas, Alex Wong, Daniel N Bolon, Jeffrey D Jensen

Genetics· March 2014

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Influenza virus drug resistance: a time-sampled population genetics perspective.
Matthieu Foll, Yu-Ping Poh, Nicholas Renzette, Anna Ferrer-Admetlla, Claudia Bank, Daniel N Bolon

PLoS Genet· February 2014

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Resistance to vemurafenib resulting from a novel mutation in the BRAFV600E kinase domain.
Timothy R Wagenaar, Leyuan Ma, Benjamin Roscoe, Sung Mi Park, Daniel N Bolon

Pigment Cell Melanoma Res· January 2014

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Evolution of the influenza A virus genome during development of oseltamivir resistance in vitro.
Nicholas Renzette, Daniel R Caffrey, Konstantin B Zeldovich, Ping Liu, Glen R Gallagher, Daniel N Bolon

J Virol· January 2014

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Designed Hsp90 heterodimers reveal an asymmetric ATPase-driven mechanism in vivo.
Parul Mishra, Daniel N A Bolon

Mol Cell· January 2014

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