Publications by authors named "Daniela Curti"

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Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain.
Giacomo Rossino, Annamaria Marra, Roberta Listro, Marco Peviani, Elena Poggio, Daniela Curti

Pharmaceuticals (Basel)· July 2023

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Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization.
Giacomo Rossino, Marta Rui, Pasquale Linciano, Daniela Rossi, Massimo Boiocchi, Daniela Curti

J Med Chem· October 2021

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Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents.
Marta Rui, Giacomo Rossino, Stefania Coniglio, Stefania Monteleone, Arianna Scuteri, Daniela Curti

Eur J Med Chem· October 2018

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Sigma Receptors as Endoplasmic Reticulum Stress "Gatekeepers" and their Modulators as Emerging New Weapons in the Fight Against Cancer.
Anna Tesei, Michela Cortesi, Alice Zamagni, Chiara Arienti, Sara Pignatta, Daniela Curti

Front Pharmacol· July 2018

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Are sigma receptor modulators a weapon against multiple sclerosis disease?
Simona Collina, Marta Rui, Silvia Stotani, Emanuele Bignardi, Daniela Rossi, Daniela Curti

Future Med Chem· November 2017

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Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents.
Marta Rui, Daniela Rossi, Annamaria Marra, Mayra Paolillo, Sergio Schinelli, Daniela Curti

Eur J Med Chem· November 2016

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Toward the identification of neuroprotective agents: g-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist.
Annamaria Marra, Daniela Rossi, Luca Pignataro, Chiara Bigogno, Annalisa Canta, Daniela Curti

Future Med Chem· October 2016

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Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists.
Annamaria Marra, Daniela Rossi, Lauretta Maggi, Federica Corana, Barbara Mannucci, Daniela Curti

Biomed Chromatogr· April 2016

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Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation.
Marco Peviani, Eleonora Salvaneschi, Leonardo Bontempi, Alessandro Petese, Antonio Manzo, Daniela Curti

Neurobiol Dis· February 2014

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Studies on the enantiomers of RC-33 as neuroprotective agents: isolation, configurational assignment, and preliminary biological profile.
Daniela Rossi, Alice Pedrali, Annamaria Marra, Luca Pignataro, Dirk Schepmann, Daniela Curti

Chirality· November 2013

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Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds: promising neuroprotective agents acting as σ₁ receptor agonists.
Daniela Rossi, Alice Pedrali, Raffaella Gaggeri, Annamaria Marra, Luca Pignataro, Daniela Curti

ChemMedChem· September 2013

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Identification of RC-33 as a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability.
Daniela Rossi, Annamaria Marra, Pietro Picconi, Massimo Serra, Laura Catenacci, Daniela Curti

Bioorg Med Chem· May 2013

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A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells.
Marika A Russo, Mayra Paolillo, Yuly Sanchez-Hernandez, Daniela Curti, Emilio Ciusani

Int J Oncol· January 2013

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Neural precursors (NPCs) from adult L967Q mice display early commitment to "in vitro" neuronal differentiation and hyperexcitability.
Francesca DiFebo, Daniela Curti, Francesca Botti, Gerardo Biella, Paolo Bigini

Exp Neurol· August 2012

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Identification of a potent and selective σ₁ receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells.
Daniela Rossi, Alice Pedrali, Mariangela Urbano, Raffaella Gaggeri, Massimo Serra, Daniela Curti

Bioorg Med Chem· November 2011

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Neural precursor-derived astrocytes of wobbler mice induce apoptotic death of motor neurons through reduced glutamate uptake.
Valentina Diana, Arianna Ottolina, Francesca Botti, Elena Fumagalli, Eleonora Calcagno, Daniela Curti

Exp Neurol· September 2010

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Endothelin B receptor antagonists block proliferation and induce apoptosis in glioma cells.
Mayra Paolillo, Marika A Russo, Daniela Curti, Cristina Lanni, Sergio Schinelli

Pharmacol Res· April 2010

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Proteomic profiling of cervical and lumbar spinal cord reveals potential protective mechanisms in the wobbler mouse, a model of motor neuron degeneration.
Antonio Bastone, Elena Fumagalli, Paolo Bigini, Pietro Perini, Davide Bernardinello, Daniela Curti

J Proteome Res· November 2009

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Modified expression of Bcl-2 and SOD1 proteins in lymphocytes from sporadic ALS patients.
Emanuela Cova, Cristina Cereda, Alberto Galli, Daniela Curti, Chiara Finotti

Neurosci Lett· May 2006

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Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease.
Barbara Santoro, Paolo Bigini, Giovanna Levandis, Vincenzo Nobile, Marco Biggiogera, Daniela Curti

Neurobiol Dis· November 2004

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Neurosphere and neurosphere-forming cells: morphological and ultrastructural characterization.
Alessandra Bez, Elena Corsini, Daniela Curti, Marco Biggiogera, Augusto Colombo

Brain Res· December 2003

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