Publications by authors named "David Bending"

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Brain-infiltrating CD4 T cells drive inflammatory microglia proliferation during cryptococcal meningitis in mice.
Sofia Hain, Man Shun Fu, Lucy Wigg, Lorna George, David Lecky, David Bending

Nat Commun· October 2025

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A pan-immunotherapy signature to predict intratumoral CD8 T cell expansions.
Munetomo Takahashi, Mikiya Tsunoda, Hiroyasu Aoki, Masaki Kurosu, Haru Ogiwara, David Bending

Nat Commun· October 2025

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Remote Force Modulation of the T-Cell Receptor Reveals an NFAT-Threshold for CD4 T-Cell Activation.
Joseph Clarke, Jeremy Pike, David Bending, Dylan Owen, David C Wraith

Eur J Immunol· June 2025

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Interferon-γ and IL-27 positively regulate type 1 regulatory T cell development during adaptive tolerance.
David A J Lecky, Lozan Sheriff, Sophie T Rouvray, Lorna S George, Alastair Copland, David Bending

iScience· May 2025

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Conserved developmental rewiring of the TCR signalosome drives tolerance in innate-like lymphocytes.
Amanpreet Singh Chawla, Harriet J Watt, Stefan A Schattgen, Neema Skariah, Irene Saha, David Bending

bioRxiv· May 2025

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Lag3 and PD-1 pathways preferentially regulate NFAT-dependent TCR signalling programmes during early CD4 T cell activation.
Lozan Sheriff, Alastair Copland, David A J Lecky, Reygn Done, Lorna S George, David Bending

Immunother Adv· March 2025

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Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression.
Catarina Gago da Graça, Amania A Sheikh, Dane M Newman, Lifen Wen, Sining Li, David Bending

Sci Immunol· January 2025

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Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity.
Alastair Copland, Gillian M Mackie, Lisa Scarfe, Elizabeth Jinks, David A J Lecky, David Bending

EMBO Mol Med· December 2024

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The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection.
Juan F Quintana, Matthew C Sinton, Praveena Chandrasegaran, Lalit Kumar Dubey, John Ogunsola, David Bending

PLoS Biol· November 2023

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T-cell response to checkpoint blockade immunotherapies: from fundamental mechanisms to treatment signatures.
Thomas A E Elliot, David A J Lecky, David Bending

Essays Biochem· September 2023

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Nr4a nuclear receptors: markers and modulators of antigen receptor signaling.
David Bending, Julie Zikherman

Curr Opin Immunol· April 2023

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T cell biomarkers come to the fore in cancer immunotherapy.
Lozan Sheriff, Alastair Copland, David Bending

Cell Rep Med· April 2023

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Nur77-Tempo mice reveal T cell steady state antigen recognition.
Thomas A E Elliot, Emma K Jennings, David A J Lecky, Sophie Rouvray, Gillian M Mackie, David Bending

Discov Immunol· December 2022

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Correction: Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits.
Carly E Whyte, Kailash Singh, Oliver T Burton, Meryem Aloulou, Lubna Kouser, David Bending

J Exp Med· August 2022

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Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation.
Nancy Gudgeon, Haydn Munford, Emma L Bishop, James Hill, Taylor Fulton-Ward, David Bending

Cell Rep· August 2022

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Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria.
Rebecca A Drummond, Jigar V Desai, Emily E Ricotta, Muthulekha Swamydas, Clay Deming, David Bending

Cell Host Microbe· July 2022

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Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits.
Carly E Whyte, Kailash Singh, Oliver T Burton, Meryem Aloulou, Lubna Kouser, David Bending

J Exp Med· July 2022

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Flow cytometric analysis of CD4+ T cell reactivation following anti-PD1 immunotherapy in a transgenic mouse model.
Lozan Sheriff, David Bending

STAR Protoc· March 2022

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Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength.
Thomas A E Elliot, Emma K Jennings, David A J Lecky, Natasha Thawait, Adriana Flores-Langarica, David Bending

Immunity· November 2021

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Application of dual -GFP -Tocky reporter mice to study T cell receptor signaling by flow cytometry.
Emma K Jennings, David A J Lecky, Masahiro Ono, David Bending

STAR Protoc· March 2021

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Nr4a1 and Nr4a3 Reporter Mice Are Differentially Sensitive to T Cell Receptor Signal Strength and Duration.
Emma Jennings, Thomas A E Elliot, Natasha Thawait, Shivani Kanabar, Juan Carlos Yam-Puc, David Bending

Cell Rep· November 2020

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Foxp3 Molecular Dynamics in Treg in Juvenile Idiopathic Arthritis.
Alastair Copland, David Bending

Front Immunol· September 2019

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Innate Lymphoid Cells and T Cells Contribute to the Interleukin-17A Signature Detected in the Synovial Fluid of Patients With Juvenile Idiopathic Arthritis.
Elizabeth C Rosser, Hannah Lom, David Bending, Chantal L Duurland, Mona Bajaj-Elliott

Arthritis Rheumatol· March 2019

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A timer for analyzing temporally dynamic changes in transcription during differentiation in vivo.
David Bending, Paz Prieto Martín, Alina Paduraru, Catherine Ducker, Erik Marzaganov

J Cell Biol· August 2018

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A temporally dynamic autoregulatory transcriptional circuit controls the effector Treg programme.
David Bending, Alina Paduraru, Catherine B Ducker, Paz Prieto Martín, Tessa Crompton

EMBO J· August 2018

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