Publications by authors named "David C Wraith"

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'Immune reset plus': the case for combining immunotherapies to maintain self-tolerance in autoimmune diseases.
Fabrina Gaspal, Parth Narendran, Sky T H Ng, Michael J Price, David C Wraith

Front Immunol· July 2025

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Antigen-specific immunotherapy of multiple sclerosis and other autoimmune diseases.
David C Wraith

Semin Arthritis Rheum· June 2025

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Remote Force Modulation of the T-Cell Receptor Reveals an NFAT-Threshold for CD4 T-Cell Activation.
Joseph Clarke, Jeremy Pike, David Bending, Dylan Owen, David C Wraith

Eur J Immunol· June 2025

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Interferon-γ and IL-27 positively regulate type 1 regulatory T cell development during adaptive tolerance.
David A J Lecky, Lozan Sheriff, Sophie T Rouvray, Lorna S George, Alastair Copland, David C Wraith

iScience· May 2025

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A dominant, pan-DR binding epitope of Der p 1 in house dust mite allergy induces tolerance in HLA-DR4 transgenic mice.
Heather B Streeter, Lora G Lucas, Robert M West, Mamidipudi T Krishna, David C Wraith

Front Immunol· April 2025

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Preclinical Development of a Tolerogenic Peptide From Glutamate Decarboxylase as a Candidate for Antigen-Specific Immunotherapy in Type 1 Diabetes.
Sky T H Ng, Michael J Price, Naomi Richardson, Maher Nawaf, Alastair Copland, David C Wraith

Diabetes· March 2025

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Incidence of immune-mediated inflammatory diseases following COVID-19: a matched cohort study in UK primary care.
Umer Syed, Anuradhaa Subramanian, David C Wraith, Janet M Lord, Kirsty McGee

BMC Med· September 2023

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SARS-CoV-2 infection is associated with anti-desmoglein 2 autoantibody detection.
Kerensa E Ward, Lora Steadman, Abid R Karim, Gary M Reynolds, Matthew Pugh, David C Wraith

Clin Exp Immunol· July 2023

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Symptoms and risk factors for long COVID in non-hospitalized adults.
Anuradhaa Subramanian, Krishnarajah Nirantharakumar, Sarah Hughes, Puja Myles, Tim Williams, David C Wraith

Nat Med· August 2022

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SARS-CoV-2 Spike- and Nucleoprotein-Specific Antibodies Induced After Vaccination or Infection Promote Classical Complement Activation.
Rachel E Lamerton, Edith Marcial-Juarez, Sian E Faustini, Marisol Perez-Toledo, Margaret Goodall, David C Wraith

Front Immunol· July 2022

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Antigen-specific immunotherapy with apitopes suppresses generation of FVIII inhibitor antibodies in HLA-transgenic mice.
Katrien Pletinckx, Kirsty S Nicolson, Heather B Streeter, William J Sanderson, Evelien Schurgers, David C Wraith

Blood Adv· April 2022

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Adaptive T cell tuning in immune regulation and immunotherapy of autoimmune diseases.
David C Wraith

Immunol Lett· April 2022

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Therapies for Long COVID in non-hospitalised individuals: from symptoms, patient-reported outcomes and immunology to targeted therapies (The TLC Study).
Shamil Haroon, Krishnarajah Nirantharakumar, Sarah E Hughes, Anuradhaa Subramanian, Olalekan Lee Aiyegbusi, David C Wraith

BMJ Open· April 2022

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Induction of Tolerance to Therapeutic Proteins With Antigen-Processing Independent T Cell Epitopes: Controlling Immune Responses to Biologics.
Evelien Schurgers, David C Wraith

Front Immunol· December 2021

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Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength.
Thomas A E Elliot, Emma K Jennings, David A J Lecky, Natasha Thawait, Adriana Flores-Langarica, David C Wraith

Immunity· November 2021

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Preclinical models of arthritis for studying immunotherapy and immune tolerance.
Gavin R Meehan, Ranjeny Thomas, Shaima Al Khabouri, Pascale Wehr, Catharien Mu Hilkens, David C Wraith

Ann Rheum Dis· October 2021

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Development of a high-sensitivity ELISA detecting IgG, IgA and IgM antibodies to the SARS-CoV-2 spike glycoprotein in serum and saliva.
Sian E Faustini, Sian E Jossi, Marisol Perez-Toledo, Adrian M Shields, Joel D Allen, David C Wraith

Immunology· September 2021

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The Mechanism of Action of Antigen Processing Independent T Cell Epitopes Designed for Immunotherapy of Autoimmune Diseases.
Ella R Shepard, Anja Wegner, Elaine V Hill, Bronwen R Burton, Sarah Aerts, David C Wraith

Front Immunol· September 2021

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Serological responses to SARS-CoV-2 following non-hospitalised infection: clinical and ethnodemographic features associated with the magnitude of the antibody response.
Adrian M Shields, Sian E Faustini, Marisol Perez-Toledo, Sian Jossi, Joel D Allen, David C Wraith

BMJ Open Respir Res· September 2021

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Establishing the prevalence of common tissue-specific autoantibodies following severe acute respiratory syndrome coronavirus 2 infection.
Alex G Richter, Adrian M Shields, Abid Karim, David Birch, Sian E Faustini, David C Wraith

Clin Exp Immunol· August 2021

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SARS-CoV-2-specific IgG1/IgG3 but not IgM in children with Pediatric Inflammatory Multi-System Syndrome.
Marisol Perez-Toledo, Sian E Faustini, Sian E Jossi, Adrian M Shields, Edith Marcial-Juarez, David C Wraith

Pediatr Allergy Immunol· July 2021

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Peptide allergen-specific immunotherapy for allergic airway diseases-State of the art.
David C Wraith, Mamidipudi T Krishna

Clin Exp Allergy· June 2021

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Manipulating antigen presentation for antigen-specific immunotherapy of autoimmune diseases.
Heather B Streeter, David C Wraith

Curr Opin Immunol· June 2021

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A LAT-Based Signaling Complex in the Immunological Synapse as Determined with Live Cell Imaging Is Less Stable in T Cells with Regulatory Capability.
Yikui Li, Helen M Tunbridge, Graham J Britton, Elaine V Hill, Parisa Sinai, David C Wraith

Cells· February 2021

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Advancement of antigen-specific immunotherapy: knowledge transfer between allergy and autoimmunity.
Naomi Richardson, David Cameron Wraith

Immunother Adv· January 2021

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