Publications by authors named "David Erle"

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Acute Respiratory Distress Syndrome Molecular Phenotypes Have Distinct Lower Respiratory Tract Transcriptomes.
Aartik Sarma, Stephanie A Christenson, Beth Zha Shoshana, Angela Pisco Oliveira, Lucile P A Neyton, David J Erle

Am J Respir Crit Care Med· December 2025

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Evaluating COVID-19 severity prediction and immune dynamics with NULISAseq: Insights from the IMPACC study.
Koji Abe, Tyson H Holmes, Tran T Nguyen, , Seunghee Kim-Schulze, David J Erle

J Immunol· December 2025

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Type 2 immune responses are associated with less severe COVID-19 in a hospitalized cohort.
Naresh Doni Jayavelu, Jingjing Qi, Carly E Milliren, Al Ozonoff, Shanshan Liu, David J Erle

J Allergy Clin Immunol Glob· November 2025

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A multiomics recovery factor predicts long COVID in the IMPACC study.
Gisela Gabernet, Jessica Maciuch, Jeremy P Gygi, John F Moore, Annmarie Hoch, David J Erle

J Clin Invest· November 2025

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Minimalistic transcriptomic signatures permit accurate early prediction of COVID-19 mortality.
Rithwik Narendra, Emily C Lydon, Hoang Van Phan, Natasha Spottiswoode, Lucile P Neyton, David Erle

JCI Insight· November 2025

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Circulating endothelial signatures correlate with worse outcomes in COVID-19, respiratory failure and ARDS.
Ana C Costa Monteiro, Harry Pickering, Aartik Sarma, Clove S Taylor, Meagan M Jenkins, David J Erle

Crit Care· October 2025

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Delirium in hospitalized COVID-19 patients is associated with dynamic changes in peripheral immune gene expression.
Sara C LaHue, Naoki Takegami, Rubinee Simmasalam, Abiya Baqai, Elena Munoz, David J Erle

Geroscience· September 2025

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MICBG406A polymorphism reduces risk of mechanical ventilation and death during viral acute lung injury.
Harry Pickering, Narges Alipanah-Lechner, Ernie Chen, Dylan Duchen, Holden T Maecker, David J Erle

JCI Insight· August 2025

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Mucus Plugs Correlate with Small Airway Remodelling in Asthma: A Case-Control Study.
Aileen Hsieh, Dragoş M Vasilescu, Jenna Barker-Mulleder, May Fouadi, Stacey Ledoux, David J Erle

Am J Respir Crit Care Med· August 2025

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High-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19.
Anita E Qualls, Tasha Tsao, Irene Lui, Shion A Lim, Yapeng Su, David J Erle

JCI Insight· July 2025

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Baseline predictors for 28-day COVID-19 severity and mortality among hospitalized patients: results from the IMPACC study.
Jintong Hou, Benjamin Haslund-Gourley, Joann Diray-Arce, Annmarie Hoch, Nadine Rouphael, David J Erle

Front Med (Lausanne)· July 2025

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Empiric Azithromycin in COVID-19 Impacts the Respiratory Microbiome and Antimicrobial Resistome without Anti-inflammatory Benefit.
Charles Langelier, Abigail Glascock, Cole Maguire, Hoang Van Phan, Emily Lydon, David Erle

Res Sq· June 2025

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Minimalistic Transcriptomic Signatures Permit Accurate Early Prediction of COVID-19 Mortality.
Rithwik Narendra, Emily C Lydon, Hoang Van Phan, Natasha Spottiswoode, Lucile P Neyton, David Erle

medRxiv· May 2025

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Identification of a multi-omics factor predictive of long COVID in the IMPACC study.
Gisela Gabernet, Jessica Maciuch, Jeremy P Gygi, John F Moore, Annmarie Hoch, David J Erle

bioRxiv· February 2025

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Machine learning models predict long COVID outcomes based on baseline clinical and immunologic factors.
Naresh Doni Jayavelu, Hady Samaha, Sonia Tandon Wimalasena, Annmarie Hoch, Jeremy P Gygi, David J Erle

medRxiv· February 2025

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Peripheral blood mononuclear cell transcriptomic trajectories reveal dynamic regulation of inflammatory actors in delirium.
Sara C LaHue, Naoki Takegami, Rubinee Simmasalam, Abiya Baqai, Elena Munoz, David J Erle

medRxiv· February 2025

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Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19.
Cole Maguire, Jing Chen, Nadine Rouphael, Harry Pickering, Hoang Van Phan, David Erle

bioRxiv· November 2024

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Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping.
Kexin Wang, Yutong Nie, Cole Maguire, Caitlin Syphurs, Heejune Sheen, David Erle

bioRxiv· November 2024

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Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia.
Natasha Spottiswoode, Alexandra Tsitsiklis, Victoria T Chu, Hoang Van Phan, Catherine DeVoe, David J Erle

Nat Commun· October 2024

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Immediate myeloid depot for SARS-CoV-2 in the human lung.
Mélia Magnen, Ran You, Arjun A Rao, Ryan T Davis, Lauren Rodriguez, David J Erle

Sci Adv· August 2024

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Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19.
Lucile P A Neyton, Ravi K Patel, Aartik Sarma, , Andrew Willmore, David J Erle

Nat Commun· June 2024

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Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study.
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, David J Erle

Nat Commun· January 2024

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Corrigendum to "Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study" [eBioMedicine 83 (2022) 104208].
Al Ozonoff, Joanna Schaenman, Naresh Doni Jayavelu, Carly E Milliren, Carolyn S Calfee, David J Erle

EBioMedicine· December 2023

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GCLiPP: global crosslinking and protein purification method for constructing high-resolution occupancy maps for RNA binding proteins.
Wandi S Zhu, Adam J Litterman, Harshaan S Sekhon, Robin Kageyama, Maya M Arce, David J Erle

Genome Biol· December 2023

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A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling.
Jason A Hackney, Haridha Shivram, Jason Vander Heiden, Chris Overall, Luz Orozco, David J Erle

iScience· October 2023

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