Publications by authors named "David Nemazee"

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Loss of promotes antitumor immunity by activating glycolysis to rescue CD8 T-cell function.
Fangkun Luan, Yunqiao Li, Jia Ning, Jenny Tuyet Tran, Tanya R Blane, David Nemazee

Life Sci Alliance· January 2026

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Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift.
Ge Song, Meng Yuan, Hejun Liu, Tazio Capozzola, Ryan N Lin, David Nemazee

Cell Rep· July 2025

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An intranasal subunit vaccine induces protective systemic and mucosal antibody immunity against respiratory viruses in mouse models.
Aina Karen Anthi, Anette Kolderup, Eline Benno Vaage, Malin Bern, Sopisa Benjakul, David Nemazee

Nat Commun· May 2025

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Blocking plasma cell fate enhances antigen-specific presentation by B cells to boost anti-tumor immunity.
Yunqiao Li, Raag Bhargava, Jenny Tuyet Tran, Tanya R Blane, Linghang Peng, David Nemazee

Nat Commun· May 2025

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Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis.
Caterina E Faliti, Maria Mesina, Jinyong Choi, Simon Bélanger, Monique A Marshall, David Nemazee

Immunity· December 2024

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Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4.
Meng Yuan, Linghang Peng, Deli Huang, Amanda Gavin, Fangkun Luan, David Nemazee

Structure· June 2024

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Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4.
Meng Yuan, Linghang Peng, Deli Huang, Amanda Gavin, Fangkun Luan, David Nemazee

bioRxiv· November 2023

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Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9.
Amanda L Gavin, Tanya R Blane, Therese C Thinnes, Emma Gerlt, Ann Marshak-Rothstein, David Nemazee

Immunohorizons· August 2023

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Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution.
Fangzhu Zhao, Meng Yuan, Celina Keating, Namir Shaabani, Oliver Limbo, David Nemazee

Sci Signal· August 2023

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Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response.
Shridhar Bale, Lifei Yang, Mehrdad Alirezaei, Richard Wilson, Takayuki Ota, David Nemazee

Front Immunol· June 2023

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Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Cherrelle Dacon, Linghang Peng, Ting-Hui Lin, Courtney Tucker, Chang-Chun D Lee, David Nemazee

Cell Host Microbe· June 2023

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Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift.
Ge Song, Meng Yuan, Hejun Liu, Tazio Capozzola, Ryan N Lin, David Nemazee

bioRxiv· April 2023

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Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Panpan Zhou, Ge Song, Hejun Liu, Meng Yuan, Wan-Ting He, David Nemazee

Immunity· March 2023

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Efficient isolation of rare B cells using next-generation antigen barcoding.
Jonathan Hurtado, Claudia Flynn, Jeong Hyun Lee, Eugenia C Salcedo, Christopher A Cottrell, David Nemazee

Front Cell Infect Microbiol· March 2023

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Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Cherrelle Dacon, Linghang Peng, Ting-Hui Lin, Courtney Tucker, Chang-Chun D Lee, David Nemazee

Cell Host Microbe· January 2023

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Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.
Fangzhu Zhao, Celina Keating, Gabriel Ozorowski, Namir Shaabani, Irene M Francino-Urdaniz, David Nemazee

iScience· September 2022

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In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice.
Alessio D Nahmad, Cicera R Lazzarotto, Natalie Zelikson, Talia Kustin, Mary Tenuta, David Nemazee

Nat Biotechnol· August 2022

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Broadly neutralizing antibodies target the coronavirus fusion peptide.
Cherrelle Dacon, Courtney Tucker, Linghang Peng, Chang-Chun D Lee, Ting-Hui Lin, David Nemazee

Science· August 2022

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Asymmetrical forward and reverse developmental trajectories determine molecular programs of B cell antigen receptor editing.
Michael K Okoreeh, Domenick E Kennedy, Akinola Olumide Emmanuel, Margaret Veselits, Azam Moshin, David Nemazee

Sci Immunol· August 2022

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Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Wan-Ting He, Meng Yuan, Sean Callaghan, Rami Musharrafieh, Ge Song, David Nemazee

Sci Transl Med· August 2022

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A broad and potent neutralization epitope in SARS-related coronaviruses.
Meng Yuan, Xueyong Zhu, Wan-Ting He, Panpan Zhou, Chengzi I Kaku, David Nemazee

Proc Natl Acad Sci U S A· July 2022

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Author Correction: A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies.
Fortunato Ferrara, M Frank Erasmus, Sara D'Angelo, Camila Leal-Lopes, André A Teixeira, David Nemazee

Nat Commun· April 2022

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Broadly neutralizing antibodies target the coronavirus fusion peptide.
Cherrelle Dacon, Courtney Tucker, Linghang Peng, Chang-Chun D Lee, Ting-Hui Lin, David Nemazee

bioRxiv· April 2022

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Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease.
Panpan Zhou, Ge Song, Wan-Ting He, Nathan Beutler, Longping V Tse, David Nemazee

bioRxiv· March 2022

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A broad and potent neutralization epitope in SARS-related coronaviruses.
Meng Yuan, Xueyong Zhu, Wan-Ting He, Panpan Zhou, Chengzi I Kaku, David Nemazee

bioRxiv· March 2022

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