Publications by authors named "David Smithson"

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Development and Qualification of Analytical Methods to Support Low Concentration Drug Product in-use Studies.
Laura Zheng, Gary Console, Christopher Wang, Kevin Whang, Hau-Ping Ting, David C Smithson

J Pharm Sci· March 2024

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Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domain.
Yu Zhao, Patrick R Cushing, David C Smithson, Maria Pellegrini, Alexandre A Pletnev

Biosci Rep· August 2018

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Correction: Cysteine modification reveals an allosteric inhibitory site on the CAL PDZ domain.
Yu Zhao, Patrick R Cushing, David C Smithson, Maria Pellegrini, Alexandre A Pletnev

Biosci Rep· August 2018

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No. 362-Ovulation Induction in Polycystic Ovary Syndrome.
David S Smithson, Tannys D R Vause, Anthony P Cheung

J Obstet Gynaecol Can· July 2018

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N 362 - Déclenchement de l'ovulation en présence d'un syndrome des ovaires polykystiques.
David S Smithson, Tannys D R Vause, Anthony P Cheung

J Obstet Gynaecol Can· July 2018

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Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening.
Diana Ortiz, W Armand Guiguemde, Jared T Hammill, Angela K Carrillo, Yizhe Chen, David C Smithson

PLoS Negl Trop Dis· December 2017

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The Impact of Standardized Acuity Assessment and a Fast-Track on Length of Stay in Obstetric Triage: A Quality Improvement Study.
David S Smithson, Rachel Twohey, Nancy Watts, Robert J Gratton

J Perinat Neonatal Nurs· June 2017

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Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum.
Jin Zhang, John J Bowling, David Smithson, Julie Clark, Melissa R Jacob

Malar J· May 2016

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Acuity Assessment in Obstetrical Triage.
Robert J Gratton, Neila Bazaracai, Ian Cameron, Nancy Watts, Colleen Brayman, David S Smithson

J Obstet Gynaecol Can· February 2016

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Development of a phenotypic high-content assay to identify pharmacoperone drugs for the treatment of primary hyperoxaluria type 1 by high-throughput screening.
Franck Madoux, Jo Ann Janovick, David Smithson, Sonia Fargue, Christopher J Danpure

Assay Drug Dev Technol· November 2015

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Transitioning pharmacoperones to therapeutic use: in vivo proof-of-principle and design of high throughput screens.
P Michael Conn, David C Smithson, Peter S Hodder, M David Stewart, Richard R Behringer

Pharmacol Res· May 2014

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Positive perception of pharmacogenetic testing for psychotropic medications.
Matthew B Lanktree, Gwyneth Zai, Laura E Vanderbeek, Daniel E Giuffra, David S Smithson

Hum Psychopharmacol· May 2014

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UPLC-MS-ELSD-PDA as a powerful dereplication tool to facilitate compound identification from small-molecule natural product libraries.
Jin Yang, Qian Liang, Mei Wang, Cynthia Jeffries, David Smithson

J Nat Prod· April 2014

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Implementing an obstetric triage acuity scale: interrater reliability and patient flow analysis.
David S Smithson, Rachel Twohey, Tim Rice, Nancy Watts, Christopher M Fernandes

Am J Obstet Gynecol· October 2013

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High-throughput screen for pharmacoperones of the vasopressin type 2 receptor.
P Michael Conn, Emery Smith, Peter Hodder, Jo Ann Janovick, David C Smithson

J Biomol Screen· September 2013

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Therapeutic rescue of misfolded/mistrafficked mutants: automation-friendly high-throughput assays for identification of pharmacoperone drugs of GPCRs.
David C Smithson, Jo Ann Janovick, P Michael Conn

Methods Enzymol· July 2013

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Optimization of the electrophile of chloronitrobenzamide leads active against Trypanosoma brucei.
Jong Yeon Hwang, David C Smithson, Gloria Holbrook, Fangyi Zhu, Michele C Connelly

Bioorg Med Chem Lett· July 2013

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Optimization of chloronitrobenzamides (CNBs) as therapeutic leads for human African trypanosomiasis (HAT).
Jong Yeon Hwang, David Smithson, Fangyi Zhu, Gloria Holbrook, Michele C Connelly

J Med Chem· April 2013

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On the mechanism of action of SJ-172550 in inhibiting the interaction of MDM4 and p53.
Michal Bista, David Smithson, Aleksandra Pecak, Gabriella Salinas, Katarzyna Pustelny

PLoS One· October 2012

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Discovery of potent and selective inhibitors of Trypanosoma brucei ornithine decarboxylase.
David C Smithson, Jeongmi Lee, Anang A Shelat, Margaret A Phillips, R Kiplin Guy

J Biol Chem· May 2010

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Chemical genetics of Plasmodium falciparum.
W Armand Guiguemde, Anang A Shelat, David Bouck, Sandra Duffy, Gregory J Crowther, David C Smithson

Nature· May 2010

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Identification and characterization of the first small molecule inhibitor of MDMX.
Damon Reed, Ying Shen, Anang A Shelat, Leggy A Arnold, Antonio M Ferreira, David C Smithson

J Biol Chem· April 2010

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Optimization of a non-radioactive high-throughput assay for decarboxylase enzymes.
David C Smithson, Anang A Shelat, Jeffrey Baldwin, Margaret A Phillips, R Kiplin Guy

Assay Drug Dev Technol· April 2010

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Automated high-throughput system to fractionate plant natural products for drug discovery.
Ying Tu, Cynthia Jeffries, Hong Ruan, Cynthia Nelson, David Smithson

J Nat Prod· April 2010

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Podophyllotoxin analogues active versus Trypanosoma brucei.
Md Jashim Uddin, David C Smithson, Kristin M Brown, Brenda C Crews, Michele Connelly

Bioorg Med Chem Lett· March 2010

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