Publications by authors named "David Standring"

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Distribution of tremorogenic activity among the major superficial muscles of the upper limb in persons with Essential tremor.
David J Standring, Adam C Pigg, Johanna Thompson-Westra, Karin Mente, Carine W Maurer

Clin Neurophysiol· October 2022

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The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-α-chloro-2'-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors.
François-René Alexandre, Eric Badaroux, John P Bilello, Stéphanie Bot, Tony Bouisset, David Standring

Bioorg Med Chem Lett· September 2017

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Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor.
Jean-Laurent Paparin, Agnès Amador, Eric Badaroux, Stéphanie Bot, Catherine Caillet, David Standring

Bioorg Med Chem Lett· June 2017

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Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.
Claire Pierra Rouvière, Agnès Amador, Eric Badaroux, Thierry Convard, Daniel Da Costa, David Standring

Bioorg Med Chem Lett· September 2016

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Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor.
Gwenaëlle Sizun, Claire Pierra, Jérôme Peyronnet, Eric Badaroux, Céline Rabeson, David Standring

Future Med Chem· July 2016

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Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor.
Cyril Dousson, François-René Alexandre, Agnès Amador, Séverine Bonaric, Stéphanie Bot, David Standring

J Med Chem· March 2016

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Discovery and structural diversity of the hepatitis C virus NS3/4A serine protease inhibitor series leading to clinical candidate IDX320.
Christophe C Parsy, François-René Alexandre, Valérie Bidau, Florence Bonnaterre, Guillaume Brandt, David Standring

Bioorg Med Chem Lett· November 2015

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Synthesis and antiviral evaluation of a novel series of homoserine-based inhibitors of the hepatitis C virus NS3/4A serine protease.
François-René Alexandre, Guillaume Brandt, Catherine Caillet, Dominique Chaves, Thierry Convard, David Standring

Bioorg Med Chem Lett· September 2015

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Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease.
Christophe Parsy, François-René Alexandre, Guillaume Brandt, Catherine Caillet, Sylvie Cappelle, David Standring

Bioorg Med Chem Lett· September 2014

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Sequence and phenotypic analysis for resistance monitoring in hepatitis C virus drug development: recommendations from the HCV DRAG.
Ann D Kwong, Isabel Najera, Jill Bechtel, Scott Bowden, Joseph Fitzgibbon, David Standring

Gastroenterology· March 2011

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Synthesis and biological evaluation of aryl-phospho-indole as novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
François-René Alexandre, Agnès Amador, Stéphanie Bot, Catherine Caillet, Thierry Convard, David Standring

J Med Chem· January 2011

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Evaluation of the role of three candidate human kinases in the conversion of the hepatitis C virus inhibitor 2'-C-methyl-cytidine to its 5'-monophosphate metabolite.
Nina L Golitsina, Francis T Danehy, Ross Fellows, Erika Cretton-Scott, David N Standring

Antiviral Res· March 2010

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Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir.
Maria Seifer, April Patty, Ilaria Serra, Bin Li, David N Standring

Antiviral Res· February 2009

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2'-C-Methyl branched pyrimidine ribonucleoside analogues: potent inhibitors of RNA virus replication.
Samira Benzaria, Dorothée Bardiot, Tony Bouisset, Clément Counor, Céline Rabeson, David Standring

Antivir Chem Chemother· May 2008

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Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.
Claire Pierra, Agnès Amador, Samira Benzaria, Erika Cretton-Scott, Marc D'Amours, David N Standring

J Med Chem· November 2006

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Synthesis, physicochemical and pharmacokinetic studies of potential prodrugs of beta-L-2'-deoxycytidine, a selective and specific anti-HBV agent.
Claire Pierra, Samira Benzaria, David Dukhan, Anna Giulia Loi, Paolo La Colla, David Standring

Antivir Chem Chemother· September 2004

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Synthesis and studies of 3'-C-trifluoromethyl nucleoside analogues bearing adenine or cytosine as the base.
Frédéric Jeannot, Gilles Gosselin, David Standring, Martin Bryant, Jean Pierre Sommadossi

Bioorg Med Chem· October 2002

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