Publications by authors named "Deborah Nguyen"

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Structure-guided allosteric modulation of the delta opioid receptor.
Jesse I Mobbs, M Deborah Nguyen, Owindeep Deo, Damian Bartuzi, Hariprasad Venugopal

bioRxiv· October 2025

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Integrating inflammatory biomarker analysis and artificial-intelligence-enabled image-based profiling to identify drug targets for intestinal fibrosis.
Shan Yu, Alexandr A Kalinin, Maria D Paraskevopoulou, Marco Maruggi, Jie Cheng, Deborah Nguyen

Cell Chem Biol· September 2023

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Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-induced fibrogenesis.
Leah M Norona, Deborah G Nguyen, David A Gerber, Sharon C Presnell, Merrie Mosedale

PLoS One· September 2019

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Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting.
Ellen M Langer, Brittany L Allen-Petersen, Shelby M King, Nicholas D Kendsersky, Megan A Turnidge, Deborah G Nguyen

Cell Rep· January 2019

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Bioprinted 3D Primary Human Intestinal Tissues Model Aspects of Native Physiology and ADME/Tox Functions.
Lauran R Madden, Theresa V Nguyen, Salvador Garcia-Mojica, Vishal Shah, Alex V Le, Deborah G Nguyen

iScience· April 2018

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Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro.
Deborah G Nguyen, Juergen Funk, Justin B Robbins, Candace Crogan-Grundy, Sharon C Presnell

PLoS One· July 2017

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3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing.
Shelby M King, J William Higgins, Celina R Nino, Timothy R Smith, Elizabeth H Paffenroth, Deborah G Nguyen

Front Physiol· March 2017

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Bioprinted three dimensional human tissues for toxicology and disease modeling.
Deborah G Nguyen, Stephen L Pentoney

Drug Discov Today Technol· March 2017

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Editor's Highlight: Modeling Compound-Induced Fibrogenesis In Vitro Using Three-Dimensional Bioprinted Human Liver Tissues.
Leah M Norona, Deborah G Nguyen, David A Gerber, Sharon C Presnell, Edward L LeCluyse

Toxicol Sci· December 2016

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Projections and opinions from 100 experts in long-acting reversible contraception.
Diana Greene Foster, Rana Barar, Heather Gould, Ivette Gomez, Deborah Nguyen

Contraception· December 2015

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G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonists reduce the production of proinflammatory cytokines and stabilize the alternative macrophage phenotype.
Klemens Högenauer, Luca Arista, Niko Schmiedeberg, Gudrun Werner, Herbert Jaksche, Deborah G Nguyen

J Med Chem· December 2014

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Discovery of trifluoromethyl(pyrimidin-2-yl)azetidine-2-carboxamides as potent, orally bioavailable TGR5 (GPBAR1) agonists: structure-activity relationships, lead optimization, and chronic in vivo efficacy.
Dean P Phillips, Wenqi Gao, Yang Yang, Guobao Zhang, Isabelle K Lerario, Deborah G Nguyen

J Med Chem· April 2014

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Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor.
Francois Gessier, Inga Preuss, Hong Yin, Mette M Rosenkilde, Stephane Laurent, Deborah G Nguyen

J Med Chem· April 2014

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Oxysterols direct immune cell migration via EBI2.
Sébastien Hannedouche, Juan Zhang, Tangsheng Yi, Weijun Shen, Deborah Nguyen

Nature· July 2011

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Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency.
Rodolfo Gonzalez, Lori L Jennings, Mark Knuth, Anthony P Orth, Heath E Klock, Deborah G Nguyen

Proc Natl Acad Sci U S A· February 2010

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Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay.
Hong Yin, Alan Chu, Wei Li, Bin Wang, Fabiola Shelton, Deborah G Nguyen

J Biol Chem· May 2009

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Identification of novel therapeutic targets for HIV infection through functional genomic cDNA screening.
Deborah G Nguyen, Hong Yin, Yingyao Zhou, Karen C Wolff, Kelli L Kuhen

Virology· May 2007

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Synthesis and biological evaluations of sulfanyltriazoles as novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
Zhiwei Wang, Baogen Wu, Kelli L Kuhen, Badry Bursulaya, Truc N Nguyen, Deborah G Nguyen

Bioorg Med Chem Lett· August 2006

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"UnPAKing" human immunodeficiency virus (HIV) replication: using small interfering RNA screening to identify novel cofactors and elucidate the role of group I PAKs in HIV infection.
Deborah G Nguyen, Karen C Wolff, Hong Yin, Jeremy S Caldwell, Kelli L Kuhen

J Virol· January 2006

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Evidence that HIV budding in primary macrophages occurs through the exosome release pathway.
Deborah Greene Nguyen, Amy Booth, Stephen J Gould, James E K Hildreth

J Biol Chem· December 2003

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Involvement of macrophage mannose receptor in the binding and transmission of HIV by macrophages.
Deborah Greene Nguyen, James E K Hildreth

Eur J Immunol· February 2003

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