Publications by authors named "Dora Games"

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Effects of α-Synuclein Immunization in a Mouse Model of Parkinson's Disease.
Eliezer Masliah, Edward Rockenstein, Anthony Adame, Michael Alford, Leslie Crews, Dora Games

Neuron· November 2025

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Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy.
Brian Spencer, Elvira Valera, Edward Rockenstein, Cassia Overk, Michael Mante, Dora Games

Acta Neuropathol Commun· January 2017

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Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models.
Dora Games, Elvira Valera, Brian Spencer, Edward Rockenstein, Michael Mante

J Neurosci· July 2014

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Vascular alterations in PDAPP mice after anti-Aβ immunotherapy: Implications for amyloid-related imaging abnormalities.
Wagner Zago, Sally Schroeter, Teresa Guido, Karen Khan, Peter Seubert, Dora Games

Alzheimers Dement· October 2013

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Axonopathy in an α-synuclein transgenic model of Lewy body disease is associated with extensive accumulation of C-terminal-truncated α-synuclein.
Dora Games, Peter Seubert, Edward Rockenstein, Christina Patrick, Margarita Trejo

Am J Pathol· March 2013

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Neutralization of soluble, synaptotoxic amyloid β species by antibodies is epitope specific.
Wagner Zago, Manuel Buttini, Thomas A Comery, Christopher Nishioka, Shyra J Gardai, Dora Games

J Neurosci· February 2012

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Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease.
Eliezer Masliah, Edward Rockenstein, Michael Mante, Leslie Crews, Brian Spencer, Dora Games

PLoS One· April 2011

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The role of animal models in advancing amyloid-beta immunotherapy to the clinic.
Dora Games, Peter Seubert

Alzheimers Res Ther· July 2010

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Faster forgetting contributes to impaired spatial memory in the PDAPP mouse: deficit in memory retrieval associated with increased sensitivity to interference?
Stephanie Daumas, Johan Sandin, Karen S Chen, Dione Kobayashi, Jane Tulloch, Dora Games

Learn Mem· September 2008

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Immunotherapy reduces vascular amyloid-beta in PDAPP mice.
Sally Schroeter, Karen Khan, Robin Barbour, Minhtam Doan, Ming Chen, Dora Games

J Neurosci· July 2008

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Antibody capture of soluble Abeta does not reduce cortical Abeta amyloidosis in the PDAPP mouse.
Peter Seubert, Robin Barbour, Karen Khan, Ruth Motter, Pearl Tang, Dora Games

Neurodegener Dis· April 2008

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Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice.
Lisa McConlogue, Manuel Buttini, John P Anderson, Elizabeth F Brigham, Karen S Chen, Dora Games

J Biol Chem· September 2007

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Active beta-amyloid immunization restores spatial learning in PDAPP mice displaying very low levels of beta-amyloid.
Guiquan Chen, Karen S Chen, Dione Kobayashi, Robin Barbour, Ruth Motter, Dora Games

J Neurosci· March 2007

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Increased T cell recruitment to the CNS after amyloid beta 1-42 immunization in Alzheimer's mice overproducing transforming growth factor-beta 1.
Marion S Buckwalter, Bronwen S Coleman, Manuel Buttini, Robin Barbour, Dale Schenk, Dora Games

J Neurosci· November 2006

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Abeta species removal after abeta42 immunization.
James A R Nicoll, Edward Barton, Delphine Boche, Jim W Neal, Isidro Ferrer, Dora Games

J Neuropathol Exp Neurol· November 2006

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Mice as models: transgenic approaches and Alzheimer's disease.
Dora Games, Manuel Buttini, Dione Kobayashi, Dale Schenk, Peter Seubert

J Alzheimers Dis· October 2006

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Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease.
Michael H Donovan, Umar Yazdani, Rebekah D Norris, Dora Games, Dwight C German

J Comp Neurol· March 2006

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The PDAPP mouse model of Alzheimer's disease: locus coeruleus neuronal shrinkage.
Dwight C German, Omar Nelson, Fen Liang, Chang-Lin Liang, Dora Games

J Comp Neurol· November 2005

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Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease.
Manuel Buttini, Eliezer Masliah, Robin Barbour, Henry Grajeda, Ruth Motter, Dora Games

J Neurosci· October 2005

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Altered APP processing in PDAPP (Val717 --> Phe) transgenic mice yields extended-length Abeta peptides.
Chera Esh, Lyle Patton, Walter Kalback, Tyler A Kokjohn, John Lopez, Dora Games

Biochemistry· October 2005

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Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
Eliezer Masliah, Edward Rockenstein, Anthony Adame, Michael Alford, Leslie Crews, Dora Games

Neuron· June 2005

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Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance.
Thierry Bussière, Frédérique Bard, Robin Barbour, Henry Grajeda, Terry Guido, Dora Games

Am J Pathol· September 2004

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Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: digital morphometric analyses.
Chi-Cheng Wu, Faisal Chawla, Dora Games, Russell E Rydel, Stephen Freedman

Proc Natl Acad Sci U S A· May 2004

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Cholinergic neuropathology in a mouse model of Alzheimer's disease.
Dwight C German, Umar Yazdani, Samuel G Speciale, Parichehr Pasbakhsh, Dora Games

J Comp Neurol· August 2003

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Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model.
John F Reilly, Dora Games, Russell E Rydel, Stephen Freedman, Dale Schenk

Proc Natl Acad Sci U S A· April 2003

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