Publications by authors named "Geoffrey Sandle"

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Ion transport and epithelial barrier dysfunction in experimental models of ulcerative colitis.
Geoffrey I Sandle, Vazhaikkurichi M Rajendran

Am J Physiol Gastrointest Liver Physiol· June 2025

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Somatostatin peptides prevent increased human colonic epithelial permeability induced by hypoxia.
Ibrahim Rajput, Vazhaikkurichi M Rajendran, Andrew J Nickerson, J Peter A Lodge, Geoffrey I Sandle

Am J Physiol Gastrointest Liver Physiol· November 2024

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Is intestinal transport dysfunctional in COVID-19-related diarrhea?
Geoffrey I Sandle, Morgan R Herod, Juan Fontana, Jonathan D Lippiat, Peter G Stockley

Am J Physiol Gastrointest Liver Physiol· May 2023

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Calmodulin Antagonist W-7 Enhances Intermediate Conductance Ca- Sensitive Basolateral Potassium Channel (IK) Activity in Human Colonic Crypts.
Kate A Bowley, Geoffrey I Sandle

J Membr Biol· August 2021

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Vitamin D Reverses Disruption of Gut Epithelial Barrier Function Caused by .
Fábia D Lobo de Sá, Steffen Backert, Praveen K Nattramilarasu, Soraya Mousavi, Geoffrey I Sandle

Int J Mol Sci· August 2021

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Parallel intermediate conductance K and Cl channel activity mediates electroneutral K exit across basolateral membranes in rat distal colon.
Shabina Rehman, Karthikeyan Narayanan, Andrew J Nickerson, Steven D Coon, Kazi Mirajul Hoque, Geoffrey I Sandle

Am J Physiol Gastrointest Liver Physiol· August 2020

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Colonic Potassium Absorption and Secretion in Health and Disease.
Vazhaikkurichi M Rajendran, Geoffrey I Sandle

Compr Physiol· September 2018

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Segmental differences in upregulated apical potassium channels in mammalian colon during potassium adaptation.
Matthew D Perry, Vazhaikkurichi M Rajendran, Kenneth A MacLennan, Geoffrey I Sandle

Am J Physiol Gastrointest Liver Physiol· November 2016

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Liddle-Mutation of the β-Subunit, but not the γ-Subunit, Attenuates Protein Kinase C-Mediated Inhibition of Human Epithelial Sodium Channels (hENaC).
Gerard G Robins, Geoffrey I Sandle

J Membr Biol· June 2016

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Upregulation of basolateral small conductance potassium channels (KCNQ1/KCNE3) in ulcerative colitis.
Adel Al-Hazza, John Linley, Qadeer Aziz, Malcolm Hunter, Geoffrey Sandle

Biochem Biophys Res Commun· February 2016

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Calcium rapidly down-regulates human renal epithelial sodium channels via a W-7-sensitive mechanism.
Gerard G Robins, Geoffrey I Sandle

J Membr Biol· August 2014

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Evidence that two distinct crypt cell types secrete chloride and potassium in human colon.
John Linley, Arun Loganathan, Shashikala Kopanati, Geoffrey I Sandle, Malcolm Hunter

Gut· March 2014

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Enhanced K(+) secretion in dextran sulfate-induced colitis reflects upregulation of large conductance apical K(+) channels (BK; Kcnma1).
Basalingappa M Kanthesh, Geoffrey I Sandle, Vazhaikkurichi M Rajendran

Am J Physiol Cell Physiol· November 2013

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Cyclic AMP-induced K+ secretion occurs independently of Cl- secretion in rat distal colon.
Geoffrey I Sandle, Vazhaikkurichi M Rajendran

Am J Physiol Cell Physiol· August 2012

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Potential role of reduced basolateral potassium (IKCa3.1) channel expression in the pathogenesis of diarrhoea in ulcerative colitis.
Adel Al-Hazza, John E Linley, Qadeer Aziz, Kenneth A Maclennan, Malcolm Hunter, Geoffrey I Sandle

J Pathol· February 2012

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Infective and inflammatory diarrhoea: mechanisms and opportunities for novel therapies.
Geoffrey I Sandle

Curr Opin Pharmacol· December 2011

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Over-expression of colonic K+ channels associated with severe potassium secretory diarrhoea after haemorrhagic shock.
Marion Simon, Jean-Paul Duong, Vincent Mallet, Raymond Jian, Kenneth A MacLennan, Geoffrey I Sandle

Nephrol Dial Transplant· October 2008

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Role of protein kinase C in aldosterone-induced non-genomic inhibition of basolateral potassium channels in human colonic crypts.
Kate A Bowley, John E Linley, Gerrard G Robins, Shashikala Kopanati, Malcolm Hunter, Geoffrey I Sandle

J Steroid Biochem Mol Biol· April 2007

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Pathogenesis of diarrhea in ulcerative colitis: new views on an old problem.
Geoffrey I Sandle

J Clin Gastroenterol· April 2005

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Dietary potassium and laxatives as regulators of colonic potassium secretion in end-stage renal disease.
Thiriloganathan Mathialahan, Geoffrey I Sandle

Nephrol Dial Transplant· February 2003

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