Publications by authors named "Gideon A Rodan"

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The discovery of MK-0674, an orally bioavailable cathepsin K inhibitor.
Elise Isabel, Kevin P Bateman, Nathalie Chauret, Wanda Cromlish, Sylvie Desmarais, Gideon A Rodan, Sevgi B Rodan

Bioorg Med Chem Lett· February 2010

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Identification of anabolic selective androgen receptor modulators with reduced activities in reproductive tissues and sebaceous glands.
Azriel Schmidt, Shun-Ichi Harada, Donald B Kimmel, Chang Bai, Fang Chen, Gideon A Rodan

J Biol Chem· December 2009

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Control of rat tail skin temperature regulation by estrogen receptor-beta selective ligand.
Evan E Opas, Angela Scafonas, Pascale V Nantermet, Robert R Wilkening, Elizabeth T Birzin, Gideon A Rodan

Maturitas· September 2009

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Agonist-like SERM effects on ERalpha-mediated repression of MMP1 promoter activity predict in vivo effects on bone and uterus.
Angela Scafonas, Alfred A Reszka, Donald B Kimmel, Xiaoli Shirley Hou, Qin Su, Gideon A Rodan

J Steroid Biochem Mol Biol· June 2008

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The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.
Jacques Yves Gauthier, Nathalie Chauret, Wanda Cromlish, Sylvie Desmarais, Le T Duong, Gideon A Rodan, Sevgi B Rodan

Bioorg Med Chem Lett· February 2008

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Involvement of alpha(v)beta3 integrins in osteoclast function.
Ichiro Nakamura, Le T Duong, Sevgi B Rodan, Gideon A Rodan

J Bone Miner Metab· December 2007

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M-CSF induces the stable interaction of cFms with alphaVbeta3 integrin in osteoclasts.
Caryn L Elsegood, Ya Zhuo, Gregg A Wesolowski, John A Hamilton, Gideon A Rodan

Int J Biochem Cell Biol· September 2006

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Relative binding affinities of bisphosphonates for human bone and relationship to antiresorptive efficacy.
Chih-Tai Leu, Eva Luegmayr, Leonard P Freedman, Gideon A Rodan, Alfred A Reszka

Bone· May 2006

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Antagonist-induced, activation function-2-independent estrogen receptor alpha phosphorylation.
Lorraine Lipfert, John E Fisher, Nan Wei, Angela Scafonas, Qin Su, Gideon A Rodan

Mol Endocrinol· March 2006

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Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis.
Tadashi Hayami, Maureen Pickarski, Ya Zhuo, Gregg A Wesolowski, Gideon A Rodan

Bone· February 2006

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Estrogenic control of thermoregulation in ERalphaKO and ERbetaKO mice.
Evan E Opas, Michael A Gentile, Donald B Kimmel, Gideon A Rodan, Azriel Schmidt

Maturitas· January 2006

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Cross-talk between an activator of nuclear receptors-mediated transcription and the D1 dopamine receptor signaling pathway.
Azriel Schmidt, Robert Vogel, Su Jane Rutledge, Evan E Opas, Gideon A Rodan

Pharmacol Biochem Behav· March 2005

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Nonpeptide alpha(v)beta3 antagonists: identification of potent, chain-shortened 7-oxo RGD mimetics.
Amy E Zartman, Le T Duong, Carmen Fernandez-Metzler, George D Hartman, Chih-Tai Leu, Gideon A Rodan, Sevgi B Rodan

Bioorg Med Chem Lett· March 2005

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Nonpeptide alpha V beta 3 antagonists. Part 9: Improved pharmacokinetic profile through the use of an aliphatic, des-amide backbone.
David B Whitman, Ben C Askew, Le T Duong, Carmen Fernandez-Metzler, Wasyl Halczenko, Gideon A Rodan, Sevgi B Rodan

Bioorg Med Chem Lett· September 2004

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Nonpeptide alpha V beta 3 antagonists. Part 10: In vitro and in vivo evaluation of a potent 7-methyl substituted tetrahydro-[1,8]naphthyridine derivative.
Michael J Breslin, Mark E Duggan, Wasyl Halczenko, George D Hartman, Le T Duong, Gideon A Rodan, Sevgi B Rodan

Bioorg Med Chem Lett· September 2004

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Nonpeptide alphavbeta3 antagonists. Part 11: discovery and preclinical evaluation of potent alphavbeta3 antagonists for the prevention and treatment of osteoporosis.
Paul J Coleman, Karen M Brashear, Ben C Askew, John H Hutchinson, Carol A McVean, Gideon A Rodan, Sevgi B Rodan

J Med Chem· September 2004

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Nitrogen-containing bisphosphonate mechanism of action.
Alfred A Reszka, Gideon A Rodan

Mini Rev Med Chem· September 2004

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The LATS2/KPM tumor suppressor is a negative regulator of the androgen receptor.
Mark Powzaniuk, Sheila McElwee-Witmer, Robert L Vogel, Tadashi Hayami, Su Jane Rutledge, Gideon A Rodan

Mol Endocrinol· August 2004

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Rat tail skin temperature regulation by estrogen, phytoestrogens and tamoxifen.
Evan E Opas, Su Jane Rutledge, Robert L Vogel, Gideon A Rodan, Azriel Schmidt

Maturitas· August 2004

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The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model.
Tadashi Hayami, Maureen Pickarski, Gregg A Wesolowski, Julia McLane, Ashleigh Bone, Gideon A Rodan

Arthritis Rheum· April 2004

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Regulatory mechanism of osteoclast activation.
Ichiro Nakamura, Gideon A Rodan, Le T Duong

J Electron Microsc (Tokyo)· March 2004

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Non-peptide alpha v beta 3 antagonists. Part 7: 3-Substituted tetrahydro-naphthyridine derivatives.
Jiabing Wang, Michael J Breslin, Paul J Coleman, Mark E Duggan, Cecilia A Hunt, Sevgi B Rodan, Gideon A Rodan

Bioorg Med Chem Lett· February 2004

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Non-peptide alpha(v)beta(3) antagonists: identification of potent, chain-shortened RGD mimetics that incorporate a central pyrrolidinone constraint.
James J Perkins, L T Duong, Carmen Fernandez-Metzler, George D Hartman, Donald B Kimmel, Gideon A Rodan, Sevgi B Rodan

Bioorg Med Chem Lett· December 2003

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Nonpeptide alphavbeta3 antagonists. 8. In vitro and in vivo evaluation of a potent alphavbeta3 antagonist for the prevention and treatment of osteoporosis.
John H Hutchinson, Wasyl Halczenko, Karen M Brashear, Michael J Breslin, Paul J Coleman, Gideon A Rodan, Sevgi B Rodan

J Med Chem· October 2003

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Mechanism of action of bisphosphonates.
Alfred A Reszka, Gideon A Rodan

Curr Osteoporos Rep· September 2003

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