Publications by authors named "Graham Trevitt"

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Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.
Natalie Page, Mark Wappett, Colin R O'Dowd, Martin O'Rourke, Gerald Gavory, Graham Trevitt

Sci Rep· September 2022

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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
Laura E de Vries, Patrick A M Jansen, Catalina Barcelo, Justin Munro, Julie M J Verhoef, Graham Trevitt

Nat Commun· April 2022

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Development of a Hypoparathyroid Male Rodent Model for Testing Delayed-Clearance PTH Molecules.
Narjes Ramezanipour, Sayyed Hamid Zarkesh Esfahani, Richard Eastell, John Newell-Price, Graham Trevitt

Endocrinology· February 2022

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A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells and Shows Antitumor Effects .
Laia Josa-Culleré, Katrina S Madden, Thomas J Cogswell, Thomas R Jackson, Tom S Carter, Graham Trevitt

J Med Chem· November 2021

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Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme.
Matthew M Hamilton, Faika Mseeh, Timothy J McAfoos, Paul G Leonard, Naphtali J Reyna, Graham Trevitt

J Med Chem· August 2021

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Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in .
Joost Schalkwijk, Erik L Allman, Patrick A M Jansen, Laura E de Vries, Julie M J Verhoef, Graham Trevitt

Sci Transl Med· September 2019

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Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases.
Marie Miglianico, Maarten Eldering, Hannah Slater, Neil Ferguson, Pauline Ambrose, Graham Trevitt

Proc Natl Acad Sci U S A· July 2018

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Enantioselective Brønsted acid-catalyzed N-acyliminium cyclization cascades.
Michael E Muratore, Chloe A Holloway, Adam W Pilling, R Ian Storer, Graham Trevitt

J Am Chem Soc· August 2009

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Atropisomeric small molecule Bcl-2 ligands: determination of bioactive conformation.
John Porter, Andrew Payne, Ian Whitcombe, Ben de Candole, Daniel Ford, Graham Trevitt

Bioorg Med Chem Lett· March 2009

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Tetrahydroisoquinoline amide substituted phenyl pyrazoles as selective Bcl-2 inhibitors.
John Porter, Andrew Payne, Ben de Candole, Daniel Ford, Brian Hutchinson, Graham Trevitt

Bioorg Med Chem Lett· January 2009

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