Publications by authors named "Gregory Donoho"

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Correction: Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Alyssa C Flint, Dana K Mitchell, Steven P Angus, Abbi E Smith, Waylan Bessler, Gregory P Donoho

Clin Cancer Res· May 2024

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Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Alyssa C Flint, Dana K Mitchell, Steven P Angus, Abbi E Smith, Waylan Bessler, Gregory P Donoho

Clin Cancer Res· September 2023

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Phase Ib/II Study of Enzalutamide with Samotolisib (LY3023414) or Placebo in Patients with Metastatic Castration-Resistant Prostate Cancer.
Christopher J Sweeney, Ivor J Percent, Sunil Babu, Jennifer L Cultrera, Bryan A Mehlhaff, Gregory P Donoho

Clin Cancer Res· June 2022

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Preclinical Evaluation and Phase Ib Study of Prexasertib, a CHK1 Inhibitor, and Samotolisib (LY3023414), a Dual PI3K/mTOR Inhibitor.
David S Hong, Kathleen N Moore, Johanna C Bendell, Daniel D Karp, Judy S Wang, Gregory P Donoho

Clin Cancer Res· April 2021

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A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib.
Wayne D Blosser, Jack A Dempsey, Ann M McNulty, Xi Rao, Philip J Ebert, Gregory P Donoho

Oncotarget· January 2020

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The Folate Pathway Inhibitor Pemetrexed Pleiotropically Enhances Effects of Cancer Immunotherapy.
David A Schaer, Sandaruwan Geeganage, Nelusha Amaladas, Zhao Hai Lu, Erik R Rasmussen, Gregory P Donoho

Clin Cancer Res· December 2019

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Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy.
Jian Du, Lei Yan, Raquel Torres, Xueqian Gong, Huimin Bian, Gregory P Donoho

Mol Cancer Ther· December 2019

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Direct analysis of PI(3,4,5)P using liquid chromatography electrospray ionization tandem mass spectrometry.
Hai H Bui, Phillip E Sanders, Diane Bodenmiller, Ming Shang Kuo, Gregory P Donoho

Anal Biochem· April 2018

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Mouse PDX Trial Suggests Synergy of Concurrent Inhibition of RAF and EGFR in Colorectal Cancer with or Mutations.
Yung-Mae M Yao, Gregory P Donoho, Philip W Iversen, Youyan Zhang, Robert D Van Horn

Clin Cancer Res· September 2017

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Characterization of LY3023414, a Novel PI3K/mTOR Dual Inhibitor Eliciting Transient Target Modulation to Impede Tumor Growth.
Michele C Smith, Mary M Mader, James A Cook, Philip Iversen, Rose Ajamie, Gregory P Donoho

Mol Cancer Ther· October 2016

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LY2603618, a selective CHK1 inhibitor, enhances the anti-tumor effect of gemcitabine in xenograft tumor models.
Darlene Barnard, H Bruce Diaz, Teresa Burke, Gregory Donoho, Richard Beckmann

Invest New Drugs· February 2016

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Intrinsic Resistance to Cixutumumab Is Conferred by Distinct Isoforms of the Insulin Receptor.
Amelie Forest, Michael Amatulli, Dale L Ludwig, Christopher B Damoci, Ying Wang, Gregory P Donoho

Mol Cancer Res· December 2015

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A Novel Eg5 Inhibitor (LY2523355) Causes Mitotic Arrest and Apoptosis in Cancer Cells and Shows Potent Antitumor Activity in Xenograft Tumor Models.
Xiang S Ye, Li Fan, Robert D Van Horn, Ryuichiro Nakai, Yoshihisa Ohta, Gregory P Donoho

Mol Cancer Ther· November 2015

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Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.
Sheng-Bin Peng, James R Henry, Michael D Kaufman, Wei-Ping Lu, Bryan D Smith, Gregory P Donoho

Cancer Cell· September 2015

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A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models.
Tinggui Yin, Maria J Lallena, Emiko L Kreklau, Kevin R Fales, Santiago Carballares, Gregory P Donoho

Mol Cancer Ther· June 2014

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Inhibition of tumor growth and metastasis in non-small cell lung cancer by LY2801653, an inhibitor of several oncokinases, including MET.
Wenjuan Wu, Chen Bi, Kelly M Credille, Jason R Manro, Victoria L Peek, Gregory P Donoho

Clin Cancer Res· October 2013

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Efficacy of low-dose oral metronomic dosing of the prodrug of gemcitabine, LY2334737, in human tumor xenografts.
Susan E Pratt, Sara Durland-Busbice, Robert L Shepard, Gregory P Donoho, James J Starling

Mol Cancer Ther· April 2013

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A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
John D Carpten, Andrew L Faber, Candice Horn, Gregory P Donoho, Stephen L Briggs

Nature· July 2007

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Positive and negative regulation of the gamma-secretase activity by nicastrin in a murine model.
Jinhe Li, Gregory J Fici, Chai-An Mao, Richard L Myers, Rongqing Shuang, Gregory P Donoho

J Biol Chem· August 2003

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