Publications by authors named "Richard Beckmann"

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Theoretical infrared spectroscopy of protonated methane isotopologues.
Richard Beckmann, Christoph Schran, Fabien Brieuc, Dominik Marx

Phys Chem Chem Phys· September 2024

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Deciphering the Impact of Helium Tagging on Flexible Molecules: Probing Microsolvation Effects of Protonated Acetylene by Quantum Configurational Entropy.
Richard Beckmann, Rafal Topolnicki, Dominik Marx

J Phys Chem A· March 2023

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Infrared Spectra at Coupled Cluster Accuracy from Neural Network Representations.
Richard Beckmann, Fabien Brieuc, Christoph Schran, Dominik Marx

J Chem Theory Comput· September 2022

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State-resolved infrared spectrum of the protonated water dimer: revisiting the characteristic proton transfer doublet peak.
Henrik R Larsson, Markus Schröder, Richard Beckmann, Fabien Brieuc, Christoph Schran

Chem Sci· September 2022

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A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib.
Wayne D Blosser, Jack A Dempsey, Ann M McNulty, Xi Rao, Philip J Ebert, Richard P Beckmann

Oncotarget· January 2020

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Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy.
Jian Du, Lei Yan, Raquel Torres, Xueqian Gong, Huimin Bian, Richard P Beckmann

Mol Cancer Ther· December 2019

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Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models.
Caitlin D Lowery, Michele Dowless, Matthew Renschler, Wayne Blosser, Alle B VanWye, Richard P Beckmann

Clin Cancer Res· April 2019

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Abemaciclib in Combination with Single-Agent Options in Patients with Stage IV Non-Small Cell Lung Cancer: A Phase Ib Study.
Edward S Kim, Karen Kelly, Luis G Paz-Ares, Pilar Garrido, Shadia Jalal, Richard Beckmann

Clin Cancer Res· November 2018

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Evaluation of Prexasertib, a Checkpoint Kinase 1 Inhibitor, in a Phase Ib Study of Patients with Squamous Cell Carcinoma.
David S Hong, Kathleen Moore, Manish Patel, Stefan C Grant, Howard A Burris, Richard Beckmann

Clin Cancer Res· July 2018

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Preclinical Activity of Abemaciclib Alone or in Combination with Antimitotic and Targeted Therapies in Breast Cancer.
Neil O'Brien, Dylan Conklin, Richard Beckmann, Tong Luo, Kevin Chau

Mol Cancer Ther· May 2018

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The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade.
David A Schaer, Richard P Beckmann, Jack A Dempsey, Lysiane Huber, Amelie Forest

Cell Rep· March 2018

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Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib.
Xueqian Gong, Lacey M Litchfield, Yue Webster, Li-Chun Chio, Swee Seong Wong, Richard P Beckmann

Cancer Cell· December 2017

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Preclinical characterization of abemaciclib in hormone receptor positive breast cancer.
Raquel Torres-Guzmán, Bruna Calsina, Ana Hermoso, Carmen Baquero, Beatriz Alvarez, Richard P Beckmann

Oncotarget· September 2017

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The Checkpoint Kinase 1 Inhibitor Prexasertib Induces Regression of Preclinical Models of Human Neuroblastoma.
Caitlin D Lowery, Alle B VanWye, Michele Dowless, Wayne Blosser, Beverly L Falcon, Richard P Beckmann

Clin Cancer Res· August 2017

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Achieving Precision Death with Cell-Cycle Inhibitors that Target DNA Replication and Repair.
Aimee Bence Lin, Samuel C McNeely, Richard P Beckmann

Clin Cancer Res· July 2017

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Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors.
Amita Patnaik, Lee S Rosen, Sara M Tolaney, Anthony W Tolcher, Jonathan W Goldman, Richard P Beckmann

Cancer Discov· July 2016

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Optimising the combination dosing strategy of abemaciclib and vemurafenib in BRAF-mutated melanoma xenograft tumours.
Sonya C Tate, Teresa F Burke, Daisy Hartman, Palaniappan Kulanthaivel, Richard P Beckmann

Br J Cancer· March 2016

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LY2603618, a selective CHK1 inhibitor, enhances the anti-tumor effect of gemcitabine in xenograft tumor models.
Darlene Barnard, H Bruce Diaz, Teresa Burke, Gregory Donoho, Richard Beckmann

Invest New Drugs· February 2016

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LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms.
Constance King, H Bruce Diaz, Samuel McNeely, Darlene Barnard, Jack Dempsey, Richard Beckmann

Mol Cancer Ther· September 2015

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Co-targeting BRAF and cyclin dependent kinases 4/6 for BRAF mutant cancers.
Vipin Yadav, Shih-Hsun Chen, Yong Gong Yue, Sean Buchanan, Richard P Beckmann

Pharmacol Ther· May 2015

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The CDK4/6 inhibitor LY2835219 overcomes vemurafenib resistance resulting from MAPK reactivation and cyclin D1 upregulation.
Vipin Yadav, Teresa F Burke, Lysiane Huber, Robert D Van Horn, Youyan Zhang, Richard P Beckmann

Mol Cancer Ther· October 2014

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Semi-mechanistic pharmacokinetic/pharmacodynamic modeling of the antitumor activity of LY2835219, a new cyclin-dependent kinase 4/6 inhibitor, in mice bearing human tumor xenografts.
Sonya C Tate, Shufen Cai, Rose T Ajamie, Teresa Burke, Richard P Beckmann

Clin Cancer Res· July 2014

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Cdk1 activity is required for mitotic activation of aurora A during G2/M transition of human cells.
Robert D Van Horn, Shaoyou Chu, Li Fan, Tinggui Yin, Jian Du, Richard Beckmann

J Biol Chem· July 2010

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Short pigment epithelial-derived factor-derived peptide inhibits angiogenesis and tumor growth.
Yelena Mirochnik, Arin Aurora, Frank T Schulze-Hoepfner, Ahmed Deabes, Victor Shifrin, Richard Beckmann

Clin Cancer Res· March 2009

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Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase.
Hui Yang, Teresa Burke, Jack Dempsey, Bruce Diaz, Elizabeth Collins, Richard Beckmann

FEBS Lett· June 2005

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