Publications by authors named "Helmut Mack"

Claim this Profile
D
Discovery of ABT-957: 1-Benzyl-5-oxopyrrolidine-2-carboxamides as selective calpain inhibitors with enhanced metabolic stability.
Katja Jantos, Andreas Kling, Helmut Mack, Wilfried Hornberger, Achim Moeller

Bioorg Med Chem Lett· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design.
Adrian D Hobson, Russell A Judge, Ana L Aguirre, Brian S Brown, Yifang Cui, Helmut Mack

J Med Chem· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mitigating the Metabolic Liability of Carbonyl Reduction: Novel Calpain Inhibitors with P1' Extension.
Andreas Kling, Katja Jantos, Helmut Mack, Wilfried Hornberger, Gisela Backfisch

ACS Med Chem Lett· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer's Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)-nicotinamides.
Andreas Kling, Katja Jantos, Helmut Mack, Wilfried Hornberger, Karla Drescher

J Med Chem· August 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats.
Victoria E Scott, Timothy A Vortherms, Wende Niforatos, Andrew M Swensen, Torben Neelands, Helmut Mack

Biochem Pharmacol· February 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of diphenyl lactam derivatives as N-type calcium channel blockers.
George A Doherty, Pramila Bhatia, Timothy A Vortherms, Kennan C Marsh, Jill M Wetter, Helmut Mack

Bioorg Med Chem Lett· February 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo.
Paul Lingor, Nicole Teusch, Katrin Schwarz, Reinhold Mueller, Helmut Mack

J Neurochem· October 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Orally active thrombin inhibitors. Part 2: optimization of the P2-moiety.
Udo E W Lange, Dorit Baucke, Wilfried Hornberger, Helmut Mack, Werner Seitz

Bioorg Med Chem Lett· May 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Orally active thrombin inhibitors. Part 1: optimization of the P1-moiety.
Helmut Mack, Dorit Baucke, Wilfried Hornberger, Udo E W Lange, Werner Seitz

Bioorg Med Chem Lett· May 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and SAR of highly potent dual 5-HT1A and 5-HT1B antagonists as potential antidepressant drugs.
Andreas Kling, Udo E W Lange, Helmut Mack, Margot H M Bakker, Karla U Drescher

Bioorg Med Chem Lett· December 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rho kinase, a promising drug target for neurological disorders.
Bernhard K Mueller, Helmut Mack, Nicole Teusch

Nat Rev Drug Discov· May 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
D-Phe-Pro-Arg type thrombin inhibitors: unexpected selectivity by modification of the P1 moiety.
Udo E W Lange, Dorit Baucke, Wilfried Hornberger, Helmut Mack, Werner Seitz

Bioorg Med Chem Lett· June 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and SAR of N-substituted dibenzazepinone derivatives as novel potent and selective alpha(V)beta(3) antagonists.
Andreas Kling, Gisela Backfisch, Jürgen Delzer, Hervé Geneste, Claudia Graef, Helmut Mack

Bioorg Med Chem Lett· February 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis