Publications by authors named "Jackson Egen"

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Editorial: The next stage of immune cell design: selective targeting of multi-antigen profiles.
Alexander Kamb, Jackson G Egen

Front Immunol· March 2025

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Corrigendum: Therapeutically targeting type I interferon directly to XCR1+ dendritic cells reveals the role of cDC1s in anti-drug antibodies.
Paul Noe, Joy H Wang, Kyu Chung, Zhiyong Cheng, Jessica J Field, Jackson G Egen

Front Immunol· June 2024

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Therapeutically targeting type I interferon directly to XCR1+ dendritic cells reveals the role of cDC1s in anti-drug antibodies.
Paul Noe, Joy H Wang, Kyu Chung, Zhiyong Cheng, Jessica J Field, Jackson G Egen

Front Immunol· November 2023

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C3/CD11b-Mediated Leishmania major Internalization by Neutrophils Induces Intraphagosomal NOX2-Mediated Respiratory Burst but Fails to Eliminate Parasites and Induces a State of Stalled Apoptosis.
Adam J Ranson, Matheus B Carneiro, Benjamin Perks, Robert Penner, Leon Melo, Jackson Egen

J Immunol· July 2023

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Autonomous IL-36R signaling in neutrophils activates potent antitumor effector functions.
Sumedha Roy, Karen Fitzgerald, Almin Lalani, Chin-Wen Lai, Aeryon Kim, Jackson Egen

J Clin Invest· June 2023

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Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity.
Jennie C Kim, Xian Liu, Karen Fitzgerald, Jason S Eng, Jessica Orf, Jackson G Egen

Cancer Immunol Immunother· May 2023

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Activity of tumor-associated macrophage depletion by CSF1R blockade is highly dependent on the tumor model and timing of treatment.
Sarah A O'Brien, Jessica Orf, Katarzyna M Skrzypczynska, Hong Tan, Jennie Kim, Jackson G Egen

Cancer Immunol Immunother· August 2021

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Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell-cold solid tumors.
Brian Belmontes, Deepali V Sawant, Wendy Zhong, Hong Tan, Anupurna Kaul, Jackson G Egen

Sci Transl Med· August 2021

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Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.
Lei Zhang, Ziyi Li, Katarzyna M Skrzypczynska, Qiao Fang, Wei Zhang, Jackson G Egen

Cell· April 2020

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Human Anti-tumor Immunity: Insights from Immunotherapy Clinical Trials.
Jackson G Egen, Wenjun Ouyang, Lawren C Wu

Immunity· January 2020

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Correction: LILRB1 Blockade Enhances Bispecific T Cell Engager Antibody-Induced Tumor Cell Killing by Effector CD8 T Cells.
Aeryon Kim, Chia-Jung Han, Ian Driver, Aleksandra Olow, Andrew K Sewell, Jackson G Egen

J Immunol· October 2019

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LILRB1 Blockade Enhances Bispecific T Cell Engager Antibody-Induced Tumor Cell Killing by Effector CD8 T Cells.
Aeryon Kim, Chia-Jung Han, Ian Driver, Aleksandra Olow, Andrew K Sewell, Jackson G Egen

J Immunol· August 2019

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TAZ is required for lung alveolar epithelial cell differentiation after injury.
Tianhe Sun, Zhiyu Huang, Hua Zhang, Clara Posner, Guiquan Jia, Jackson G Egen

JCI Insight· June 2019

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Breaking self-tolerance during autoimmunity and cancer immunity: Myeloid cells and type I IFN response regulation.
Kristin V Tarbell, Jackson G Egen

J Leukoc Biol· February 2018

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CXCL14 is a candidate biomarker for Hedgehog signalling in idiopathic pulmonary fibrosis.
Guiquan Jia, Sanjay Chandriani, Alexander R Abbas, Daryle J DePianto, Elsa N N'Diaye, Jackson G Egen

Thorax· September 2017

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Use of two-photon microscopy to study Leishmania major infection of the skin.
Matheus Batista Carneiro, Leah Shan Hohman, Jackson G Egen, Nathan C Peters

Methods· August 2017

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αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis.
Christopher A Lamb, John C Mansfield, Gaik W Tew, Deena Gibbons, Anna K Long, Jackson G Egen

J Crohns Colitis· May 2017

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Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis.
Gaik W Tew, Jason A Hackney, Deena Gibbons, Christopher A Lamb, Diana Luca, Jackson G Egen

Gastroenterology· February 2016

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Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.
Daniel Lafkas, Amy Shelton, Cecilia Chiu, Gladys de Leon Boenig, Yongmei Chen, Jackson Egen

Nature· December 2015

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TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma.
David F Choy, Kevin M Hart, Lee A Borthwick, Aarti Shikotra, Deepti R Nagarkar, Jackson G Egen

Sci Transl Med· August 2015

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Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis.
Daryle J DePianto, Sanjay Chandriani, Alexander R Abbas, Guiquan Jia, Elsa N N'Diaye, Jackson G Egen

Thorax· January 2015

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Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial.
Séverine Vermeire, Sharon O'Byrne, Mary Keir, Marna Williams, Timothy T Lu, Jackson G Egen

Lancet· July 2014

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Endogenously expressed IL-13Rα2 attenuates IL-13-mediated responses but does not activate signaling in human lung fibroblasts.
Sanjay Chandriani, Daryle J DePianto, Elsa N N'Diaye, Alexander R Abbas, Janet Jackman, Jackson G Egen

J Immunol· July 2014

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Pathogen-related differences in the abundance of presented antigen are reflected in CD4+ T cell dynamic behavior and effector function in the lung.
Parizad Torabi-Parizi, Nienke Vrisekoop, Wolfgang Kastenmuller, Michael Y Gerner, Jackson G Egen

J Immunol· February 2014

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Tuning of antigen sensitivity by T cell receptor-dependent negative feedback controls T cell effector function in inflamed tissues.
Tetsuya Honda, Jackson G Egen, Tim Lämmermann, Wolfgang Kastenmüller, Parizad Torabi-Parizi

Immunity· February 2014

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