Publications by authors named "James Shoblock"

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Characterization of a Selective, Orally Available, and Brain Penetrant Small Molecule GPR139 Agonist.
James R Shoblock, Natalie Welty, Ian Fraser, Ryan Wyatt, Brian Lord

Front Pharmacol· March 2019

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Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia.
Pascal Bonaventure, Jonathan Shelton, Sujin Yun, Diane Nepomuceno, Steven Sutton, James Shoblock

J Pharmacol Exp Ther· September 2015

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Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.
Brian Lord, Leah Aluisio, James R Shoblock, Robert A Neff, Elena I Varlinskaya

J Pharmacol Exp Ther· December 2014

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Pharmacological or genetic orexin1 receptor inhibition attenuates MK-801 induced glutamate release in mouse cortex.
Leah Aluisio, Ian Fraser, Tamara Berdyyeva, Volha Tryputsen, Brock T Shireman, James Shoblock

Front Neurosci· June 2014

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PET brain imaging of neuropeptide Y2 receptors using N-11C-methyl-JNJ-31020028 in pigs.
Michael Winterdahl, Hélène Audrain, Anne M Landau, Donald F Smith, Pascal Bonaventure, James R Shoblock

J Nucl Med· April 2014

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Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567.
Anindya Bhattacharya, Qi Wang, Hong Ao, James R Shoblock, Brian Lord

Br J Pharmacol· October 2013

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In vitro pharmacological characterization of RXFP3 allosterism: an example of probe dependency.
Lily Alvarez-Jaimes, Steven W Sutton, Diane Nepomuceno, S Timothy Motley, Miroslav Cik, James Shoblock

PLoS One· July 2012

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Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission.
Pascal Bonaventure, Leah Aluisio, James Shoblock, Jamin D Boggs, Ian C Fraser

PLoS One· October 2011

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Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement.
James R Shoblock, Natalie Welty, Leah Aluisio, Ian Fraser, S Timothy Motley

Psychopharmacology (Berl)· May 2011

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JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.
Ruggero Galici, Amir H Rezvani, Leah Aluisio, Brian Lord, Edward D Levin, James R Shoblock

Psychopharmacology (Berl)· April 2011

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In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor.
James R Shoblock, Natalie Welty, Diane Nepomuceno, Brian Lord, Leah Aluisio

Psychopharmacology (Berl)· February 2010

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The effects of thioperamide on extracellular levels of glutamate and GABA in the rat prefrontal cortex.
Natalie Welty, James R Shoblock

Psychopharmacology (Berl)· December 2009

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The pharmacology of Ro 64-6198, a systemically active, nonpeptide NOP receptor (opiate receptor-like 1, ORL-1) agonist with diverse preclinical therapeutic activity.
James R Shoblock

CNS Drug Rev· July 2007

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Constitutively active micro opioid receptors mediate the enhanced conditioned aversive effect of naloxone in morphine-dependent mice.
James R Shoblock, Nigel T Maidment

Neuropsychopharmacology· January 2006

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The effect of a systemically active ORL-1 agonist, Ro 64-6198, on the acquisition, expression, extinction, and reinstatement of morphine conditioned place preference.
James R Shoblock, Jürgen Wichmann, Nigel T Maidment

Neuropharmacology· September 2005

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Differential interactions of desipramine with amphetamine and methamphetamine: evidence that amphetamine releases dopamine from noradrenergic neurons in the medial prefrontal cortex.
James R Shoblock, Isabelle M Maisonneuve, Stanley D Glick

Neurochem Res· July 2004

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Differences between d-methamphetamine and d-amphetamine in rats: working memory, tolerance, and extinction.
James R Shoblock, Isabelle M Maisonneuve, Stanley D Glick

Psychopharmacology (Berl)· November 2003

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Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats.
James R Shoblock, Eric B Sullivan, Isabelle M Maisonneuve, Stanley D Glick

Psychopharmacology (Berl)· February 2003

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