Publications by authors named "James T Patterson"

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Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis.
Suzanne Edavettal, Pilar Cejudo-Martin, Bidisha Dasgupta, Danlin Yang, Matthew D Buschman, James T Patterson

Med· December 2022

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PSMA-targeted bispecific Fab conjugates that engage T cells.
James T Patterson, Jason Isaacson, Lisa Kerwin, Ghazi Atassi, Rohit Duggal

Bioorg Med Chem Lett· December 2017

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Chemically generated IgG2 bispecific antibodies through disulfide bridging.
James T Patterson, Edwige Gros, Heyue Zhou, Ghazi Atassi, Lisa Kerwin

Bioorg Med Chem Lett· August 2017

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Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation.
James T Patterson, Henry D Wilson, Shigehiro Asano, Napon Nilchan, Roberta P Fuller

Bioconjug Chem· October 2016

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Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues.
Xiuling Li, James T Patterson, Mohosin Sarkar, Lee Pedzisa, Thomas Kodadek

Bioconjug Chem· November 2015

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Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering.
Jia Liu, Thomas Gaj, James T Patterson, Shannon J Sirk, Carlos F Barbas

PLoS One· January 2015

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Site-selective labeling of a lysine residue in human serum albumin.
Shigehiro Asano, James T Patterson, Thomas Gaj, Carlos F Barbas

Angew Chem Int Ed Engl· October 2014

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Improving the serum stability of site-specific antibody conjugates with sulfone linkers.
James T Patterson, Shigehiro Asano, Xiuling Li, Christoph Rader, Carlos F Barbas

Bioconjug Chem· August 2014

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A hydrophobic site on the GLP-1 receptor extracellular domain orients the peptide ligand for signal transduction.
James T Patterson, Pengyun Li, Jonathan W Day, Vasily M Gelfanov, Richard D Dimarchi

Mol Metab· November 2013

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Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic β-cells.
Ramya S Kuna, Shravan Babu Girada, Suman Asalla, Joyprashant Vallentyne, Subbareddy Maddika, James T Patterson

Am J Physiol Endocrinol Metab· July 2013

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Functional association of the N-terminal residues with the central region in glucagon-related peptides.
James T Patterson, Jonathan W Day, Vasily M Gelfanov, Richard D DiMarchi

J Pept Sci· October 2011

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Charge inversion at position 68 of the glucagon and glucagon-like peptide-1 receptors supports selectivity in hormone action.
Jonathan W Day, Pengyun Li, James T Patterson, Joe Chabenne, Maria Dimarchi Chabenne

J Pept Sci· March 2011

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A novel human-based receptor antagonist of sustained action reveals body weight control by endogenous GLP-1.
James T Patterson, Nickki Ottaway, Vasily M Gelfanov, David L Smiley, Diego Perez-Tilve

ACS Chem Biol· February 2011

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Template-directed ligation of tethered mononucleotides by t4 DNA ligase for kinase ribozyme selection.
David G Nickens, Nirmala Bardiya, James T Patterson, Donald H Burke

PLoS One· August 2010

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Melanocortin signaling in the CNS directly regulates circulating cholesterol.
Diego Perez-Tilve, Susanna M Hofmann, Joshua Basford, Ruben Nogueiras, Paul T Pfluger, James T Patterson

Nat Neurosci· July 2010

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A new glucagon and GLP-1 co-agonist eliminates obesity in rodents.
Jonathan W Day, Nickki Ottaway, James T Patterson, Vasily Gelfanov, David Smiley

Nat Chem Biol· October 2009

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Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity.
Ruben Nogueiras, Diego Pérez-Tilve, Christelle Veyrat-Durebex, Donald A Morgan, Luis Varela, James T Patterson

J Neurosci· May 2009

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HIV-1 reverse transcriptase pausing at bulky 2' adducts is relieved by deletion of the RNase H domain.
James T Patterson, David G Nickens, Donald H Burke

RNA Biol· October 2006

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HIV-1 inactivation by nucleic acid aptamers.
Daniel M Held, Jay D Kissel, James T Patterson, David G Nickens, Donald H Burke

Front Biosci· January 2006

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Inhibition of HIV-1 reverse transcriptase by RNA aptamers in Escherichia coli.
David G Nickens, James T Patterson, Donald H Burke

RNA· September 2003

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