Publications by authors named "Jonathan W Day"

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Targeting the angiopoietin-like protein 3/8 complex with a monoclonal antibody in patients with mixed hyperlipidemia: a phase 1 trial.
Daniel Gaudet, Malgorzata Gonciarz, Xi Shen, Jennifer K Leohr, Thomas P Beyer, Jonathan W Day

Nat Med· August 2025

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Preclinical Characterization of LY3209590, a Novel Weekly Basal Insulin Fc-Fusion Protein.
Julie S Moyers, Ryan J Hansen, Jonathan W Day, Craig D Dickinson, Chen Zhang

J Pharmacol Exp Ther· September 2022

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An anti-ANGPTL3/8 antibody decreases circulating triglycerides by binding to a LPL-inhibitory leucine zipper-like motif.
Deepa Balasubramaniam, Oliver Schroeder, Anna M Russell, Jonathan R Fitchett, Aaron K Austin, Jonathan W Day

J Lipid Res· May 2022

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Optimization of co-agonism at GLP-1 and glucagon receptors to safely maximize weight reduction in DIO-rodents.
Jonathan W Day, Vasily Gelfanov, David Smiley, Paul E Carrington, George Eiermann

Biopolymers· April 2014

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A hydrophobic site on the GLP-1 receptor extracellular domain orients the peptide ligand for signal transduction.
James T Patterson, Pengyun Li, Jonathan W Day, Vasily M Gelfanov, Richard D Dimarchi

Mol Metab· November 2013

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Identification of metal ion binding peptides containing unnatural amino acids by phage display.
Jonathan W Day, Chan Hyuk Kim, Vaughn V Smider, Peter G Schultz

Bioorg Med Chem Lett· May 2013

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Functional association of the N-terminal residues with the central region in glucagon-related peptides.
James T Patterson, Jonathan W Day, Vasily M Gelfanov, Richard D DiMarchi

J Pept Sci· October 2011

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Charge inversion at position 68 of the glucagon and glucagon-like peptide-1 receptors supports selectivity in hormone action.
Jonathan W Day, Pengyun Li, James T Patterson, Joe Chabenne, Maria Dimarchi Chabenne

J Pept Sci· March 2011

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A new glucagon and GLP-1 co-agonist eliminates obesity in rodents.
Jonathan W Day, Nickki Ottaway, James T Patterson, Vasily Gelfanov, David Smiley

Nat Chem Biol· October 2009

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