Publications by authors named "James W Perfield"

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Lipid droplet targeting of the lipase coactivator ABHD5 and the fatty liver disease-causing variant PNPLA3 I148M is required to promote liver steatosis.
Grace Teskey, Nivedita Tiwari, Andrew J Butcko, Amit Kumar, Anuradha Yadav, James W Perfield

J Biol Chem· February 2025

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Characterization of six clinical drugs and dietary intervention in the nonobese CDAA-HFD mouse model of MASH and progressive fibrosis.
Malte Hasle Nielsen, Jacob Nøhr-Meldgaard, Mathias Bonde Møllerhøj, Denise Oró, Susanne E Pors, James W Perfield

Am J Physiol Gastrointest Liver Physiol· January 2025

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Lipid droplet targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis.
Grace Teskey, Nivedita Tiwari, Andrew J Butcko, Amit Kumar, Anu Yadav, James W Perfield

bioRxiv· November 2024

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Choline-deficient, high-fat diet-induced MASH in Göttingen Minipigs: characterization and effects of a chow reversal period.
Henning Hvid, Sara T Hjuler, Pierre Bedossa, Dina G Tiniakos, Ioannis Kamzolas, James W Perfield

Am J Physiol Gastrointest Liver Physiol· October 2024

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An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD).
Michele Vacca, Ioannis Kamzolas, Lea Mørch Harder, Fiona Oakley, Christian Trautwein, James W Perfield

Nat Metab· June 2024

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Fibroblast growth factor-21 improves insulin action in nonlactating ewes.
Cassandra L Lamb, Sarah L Giesy, Molly M McGuckin, James W Perfield, Anthony Butterfield

Am J Physiol Regul Integr Comp Physiol· March 2022

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The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis.
Patrick J Antonellis, Brian A Droz, Richard Cosgrove, Libbey S O'Farrell, Tamer Coskun, James W Perfield

Mol Metab· December 2019

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Fibroblast growth factor 21 increases hepatic oxidative capacity but not physical activity or energy expenditure in hepatic peroxisome proliferator-activated receptor γ coactivator-1α-deficient mice.
Justin A Fletcher, Melissa A Linden, Ryan D Sheldon, Grace M Meers, E Matthew Morris, James W Perfield

Exp Physiol· March 2018

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Anti-inflammatory effects of exercise training in adipose tissue do not require FGF21.
Jay W Porter, Joe L Rowles, Justin A Fletcher, Terese M Zidon, Nathan C Winn, James W Perfield

J Endocrinol· November 2017

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Effect of circulating glucagon and free fatty acids on hepatic FGF21 production in dairy cows.
Luciano S Caixeta, Sarah L Giesy, Christopher S Krumm, James W Perfield, Anthony Butterfield

Am J Physiol Regul Integr Comp Physiol· November 2017

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FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans.
Ricardo J Samms, Jo E Lewis, Luke Norton, Francis B Stephens, Christopher J Gaffney, James W Perfield

J Clin Endocrinol Metab· October 2017

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Transcriptomic differences in intra-abdominal adipose tissue in extremely obese adolescents with different stages of NAFLD.
Ryan D Sheldon, Kayla M Kanosky, Kevin D Wells, Lili Miles, James W Perfield

Physiol Genomics· December 2016

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Fibroblast growth factor 21 and exercise-induced hepatic mitochondrial adaptations.
Justin A Fletcher, Melissa A Linden, Ryan D Sheldon, Grace M Meers, E Matthew Morris, James W Perfield

Am J Physiol Gastrointest Liver Physiol· May 2016

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Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1.
Ricardo J Samms, Dennis P Smith, Christine C Cheng, Patrick P Antonellis, James W Perfield

Cell Rep· May 2015

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Unique transcriptomic signature of omental adipose tissue in Ossabaw swine: a model of childhood obesity.
Ryan G Toedebusch, Michael D Roberts, Kevin D Wells, Joseph M Company, Kayla M Kanosky, James W Perfield

Physiol Genomics· May 2014

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Altered hepatic lipid metabolism contributes to nonalcoholic fatty liver disease in leptin-deficient Ob/Ob mice.
James W Perfield, Laura C Ortinau, R Taylor Pickering, Meghan L Ruebel, Grace M Meers

J Obes· July 2013

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Vascular transcriptional alterations produced by juvenile obesity in Ossabaw swine.
Jaume Padilla, Nathan T Jenkins, Sewon Lee, Hanrui Zhang, Jian Cui, James W Perfield

Physiol Genomics· June 2013

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Sterculic Oil, a Natural SCD1 Inhibitor, Improves Glucose Tolerance in Obese ob/ob Mice.
Laura C Ortinau, R Taylor Pickering, Karen J Nickelson, Kelly L Stromsdorfer, Chaitasi Y Naik, James W Perfield

ISRN Endocrinol· December 2012

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A comparison of inflammatory and oxidative stress markers in adipose tissue from weight-matched obese male and female mice.
Karen J Nickelson, Kelly L Stromsdorfer, R Taylor Pickering, Tzu-Wen Liu, Laura C Ortinau, James W Perfield

Exp Diabetes Res· October 2012

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Conversion of t11t13 CLA into c9t11 CLA in Caco-2 cells and inhibition by sterculic oil.
Anne-Catherine Schneider, Pauline Beguin, Sophie Bourez, James W Perfield, Eric Mignolet

PLoS One· August 2012

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Exercise and Omega-3 Polyunsaturated Fatty Acid Supplementation for the Treatment of Hepatic Steatosis in Hyperphagic OLETF Rats.
Sarah J Borengasser, R Scott Rector, Grace M Uptergrove, E Matthew Morris, James W Perfield

J Nutr Metab· November 2011

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Tumor progression locus 2 (TPL2) regulates obesity-associated inflammation and insulin resistance.
James W Perfield, Yunkyoung Lee, Gerald I Shulman, Varman T Samuel, Michael J Jurczak

Diabetes· April 2011

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Perilipin overexpression in white adipose tissue induces a brown fat-like phenotype.
Takashi Sawada, Hideaki Miyoshi, Kohei Shimada, Akira Suzuki, Yuko Okamatsu-Ogura, James W Perfield

PLoS One· November 2010

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Loss of ovarian function in mice results in abrogated skeletal muscle PPARdelta and FoxO1-mediated gene expression.
Nicole H Rogers, James W Perfield, Katherine J Strissel, Martin S Obin, Andrew S Greenberg

Biochem Biophys Res Commun· January 2010

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Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity.
Olga V Danilova, Albert K Tai, Deanna A Mele, Martin Beinborn, Andrew B Leiter, James W Perfield

Endocrinology· December 2009

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