Publications by authors named "Jason Gay"

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Nivolumab plus ipilimumab induce hyper-progression in renal medullary carcinoma: results of a phase II trial and preclinical evidence.
Melinda Soeung, Xinmiao Yan, Ciro Zanca, Jing Qian, Menuka Karki, Jason P Gay

Nat Commun· November 2025

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Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis.
Ziheng Chen, I-Lin Ho, Melinda Soeung, Er-Yen Yen, Jintan Liu, Jason P Gay

Nat Commun· April 2023

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Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials.
Timothy A Yap, Naval Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Jason P Gay

Nat Med· January 2023

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Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia.
Natalia Baran, Alessia Lodi, Yogesh Dhungana, Shelley Herbrich, Meghan Collins, Jason Gay

Nat Commun· May 2022

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Feasibility of administering human pancreatic cancer chemotherapy in a spontaneous pancreatic cancer mouse model.
Abagail M Delahoussaye, Joseph Abi Jaoude, Morgan Green, Tara N Fujimoto, Jessica Molkentine, Jason P Gay

BMC Cancer· February 2022

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PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma.
Virginia Giuliani, Meredith A Miller, Chiu-Yi Liu, Stella R Hartono, Caleb A Class, Jason P Gay

Nat Commun· July 2021

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Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties.
Michael J Soth, Kang Le, Maria Emilia Di Francesco, Matthew M Hamilton, Gang Liu, Jason P Gay

J Med Chem· November 2020

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Author Correction: Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer.
Yonathan Lissanu Deribe, Yuting Sun, Christopher Terranova, Fatima Khan, Juan Martinez-Ledesma, Jason Gay

Nat Med· October 2018

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Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer.
Yonathan Lissanu Deribe, Yuting Sun, Christopher Terranova, Fatima Khan, Juan Martinez-Ledesma, Jason Gay

Nat Med· July 2018

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An inhibitor of oxidative phosphorylation exploits cancer vulnerability.
Jennifer R Molina, Yuting Sun, Marina Protopopova, Sonal Gera, Madhavi Bandi, Jason Gay

Nat Med· July 2018

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Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque.
David R Powell, Jason P Gay, Melinda Smith, Nathaniel Wilganowski, Angela Harris

Diabetes Metab Syndr Obes· July 2016

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Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models.
Michael S Lee, Timothy L Helms, Ningping Feng, Jason Gay, Qing Edward Chang

Oncotarget· June 2016

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Design, synthesis, and in vivo activity of novel inhibitors of delta-5 desaturase for the treatment of metabolic syndrome.
Simon D P Baugh, Praveen K Pabba, Joseph Barbosa, Eric Coulter, Urvi Desai, Jason P Gay

Bioorg Med Chem Lett· September 2015

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Diacylglycerol Lipase α Knockout Mice Demonstrate Metabolic and Behavioral Phenotypes Similar to Those of Cannabinoid Receptor 1 Knockout Mice.
David R Powell, Jason P Gay, Nathaniel Wilganowski, Deon Doree, Katerina V Savelieva

Front Endocrinol (Lausanne)· June 2015

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Silver negative pressure dressing with vacuum-assisted closure of massive pelvic and extremity wounds.
Herrick J Siegel, Diego F Herrera, Jason Gay

Clin Orthop Relat Res· March 2014

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Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4.
Luciano F Drager, Qiaoling Yao, Karen L Hernandez, Mi-Kyung Shin, Shannon Bevans-Fonti, Jason Gay

Am J Respir Crit Care Med· July 2013

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Effect of chronic intermittent hypoxia on triglyceride uptake in different tissues.
Qiaoling Yao, Mi-Kyung Shin, Jonathan C Jun, Karen L Hernandez, Neil R Aggarwal, Jason Gay

J Lipid Res· April 2013

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Improved glycemic control in mice lacking Sglt1 and Sglt2.
David R Powell, Christopher M DaCosta, Jason Gay, Zhi-Ming Ding, Melinda Smith

Am J Physiol Endocrinol Metab· January 2013

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GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4.
William K Sonnenburg, Daiguan Yu, E-Chiang Lee, Wei Xiong, Gennady Gololobov, Jason Gay

J Lipid Res· December 2009

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Identification of a new functional domain in angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) involved in binding and inhibition of lipoprotein lipase (LPL).
E-Chiang Lee, Urvi Desai, Gennady Gololobov, Seokjoo Hong, Xiao Feng, Jason Gay

J Biol Chem· May 2009

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Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice.
Urvi Desai, E-Chiang Lee, Kyu Chung, Cuihua Gao, Jason Gay

Proc Natl Acad Sci U S A· July 2007

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Rapid development of glomerular injury and renal failure in mice lacking p53R2.
David R Powell, Urvi Desai, Mary Jean Sparks, Gwenn Hansen, Jason Gay

Pediatr Nephrol· March 2005

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Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis.
Thea M Goepfert, Yetunde E Adigun, Ling Zhong, Jason Gay, Daniel Medina

Cancer Res· July 2002

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Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis.
Lakshmi Sivaraman, Jason Gay, Susan G Hilsenbeck, H David Shine, Orla M Conneely

Breast Cancer Res Treat· May 2002

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