Publications by authors named "Jason J Pitt"

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A multi-task domain-adapted model to predict chemotherapy response from mutations in recurrently altered cancer genes.
Aishwarya Jayagopal, Robert J Walsh, Krishna Kumar Hariprasannan, Ragunathan Mariappan, Debabrata Mahapatra, Jason J Pitt

iScience· March 2025

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Melvin is a conversational voice interface for cancer genomics data.
Akila R Perera, Vinay Warrier, Shwetha Sundararaman, Yi Hsiao, Soumita Ghosh, Jason J Pitt

Commun Biol· January 2024

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Mutational signature assignment heterogeneity is widespread and can be addressed by ensemble approaches.
Andy J Wu, Akila Perera, Linganesan Kularatnarajah, Anna Korsakova, Jason J Pitt

Brief Bioinform· September 2023

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Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma.
Michal Marek Hoppe, Patrick Jaynes, Fan Shuangyi, Yanfen Peng, Shruti Sridhar, Jason J Pitt

Cancer Discov· May 2023

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Immune pathway upregulation and lower genomic instability distinguish EBV-positive nodal T/NK-cell lymphoma from ENKTL and PTCL-NOS.
Cho Mar Myint Wai, Shangying Chen, The Phyu, Shuangyi Fan, Sai Mun Leong, Jason J Pitt

Haematologica· August 2022

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Pan-cancer pervasive upregulation of 3' UTR splicing drives tumourigenesis.
Jia Jia Chan, Bin Zhang, Xiao Hong Chew, Adil Salhi, Zhi Hao Kwok, Jason J Pitt

Nat Cell Biol· June 2022

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Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes.
Naser Ansari-Pour, Yonglan Zheng, Toshio F Yoshimatsu, Ayodele Sanni, Mustapha Ajani, Jason J Pitt

Nat Commun· November 2021

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Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation.
Nisha Padmanabhan, Huang Kie Kyon, Arnoud Boot, Kevin Lim, Supriya Srivastava, Jason J Pitt

Genome Biol· June 2021

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Author Correction: Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation.
Nisha Padmanabhan, Huang Kie Kyon, Arnoud Boot, Kevin Lim, Supriya Srivastava, Jason J Pitt

Genome Biol· June 2021

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Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer.
Michal M Hoppe, Patrick Jaynes, Joanna D Wardyn, Sai Srinivas Upadhyayula, Tuan Zea Tan, Jason J Pitt

EMBO Mol Med· May 2021

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Germline variants and somatic mutation signatures of breast cancer across populations of African and European ancestry in the US and Nigeria.
Shengfeng Wang, Jason J Pitt, Yonglan Zheng, Toshio F Yoshimatsu, Guimin Gao

Int J Cancer· December 2019

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Author Correction: Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.
Jason J Pitt, Markus Riester, Yonglan Zheng, Toshio F Yoshimatsu, Ayodele Sanni

Nat Commun· January 2019

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Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.
Jiqiu Cheng, Jonas Demeulemeester, David C Wedge, Hans Kristian M Vollan, Jason J Pitt

Nat Commun· January 2019

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Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.
Jiqiu Cheng, Jonas Demeulemeester, David C Wedge, Hans Kristian M Vollan, Jason J Pitt

Nat Commun· December 2018

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Genetic Ancestry May Influence the Evolutionary Trajectory of Cancers.
Jason J Pitt, Yonglan Zheng, Olufunmilayo I Olopade

Cancer Cell· October 2018

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Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.
Jason J Pitt, Markus Riester, Yonglan Zheng, Toshio F Yoshimatsu, Ayodele Sanni

Nat Commun· October 2018

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Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas.
Dezheng Huo, Hai Hu, Suhn K Rhie, Eric R Gamazon, Andrew D Cherniack, Jason J Pitt

JAMA Oncol· December 2017

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Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.
Jiqiu Cheng, Jonas Demeulemeester, David C Wedge, Hans Kristian M Vollan, Jason J Pitt

Nat Commun· October 2017

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Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity.
Oliver Ou, Konrad Huppi, Sirisha Chakka, Kristen Gehlhaus, Wendy Dubois, Jason J Pitt

Cancer Lett· November 2014

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Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening.
Sireesha V Garimella, Kristie Gehlhaus, Jennifer L Dine, Jason J Pitt, Magdalena Grandin

Breast Cancer Res· April 2014

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Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer.
Jordi Camps, Jason J Pitt, Georg Emons, Amanda B Hummon, Chanelle M Case

Cancer Res· March 2013

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The 8q24 gene desert: an oasis of non-coding transcriptional activity.
Konrad Huppi, Jason J Pitt, Brady M Wahlberg, Natasha J Caplen

Front Genet· October 2012

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Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.
Amanda B Hummon, Jason J Pitt, Jordi Camps, Georg Emons, Susan B Skube

Mol Cancer· January 2012

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Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA.
Mark Mackiewicz, Konrad Huppi, Jason J Pitt, Tiffany H Dorsey, Stefan Ambs

Breast Cancer Res Treat· November 2011

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