Publications by authors named "Jean Regard"

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Discovery of a novel, highly potent and orally bioavailable pyrrolidinone indole series of irreversible Myeloperoxidase (MPO) inhibitors.
Jean B Regard, Tyler J Harrison, Jake Axford, Laura Axford, Lac Lee

Biochem Pharmacol· March 2023

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Interleukin-1 (IL-1) and the inflammasome in cancer.
Vincent Pretre, Dimitrios Papadopoulos, Jean Regard, Marc Pelletier, Janghee Woo

Cytokine· May 2022

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Discovery of a novel indole pharmacophore for the irreversible inhibition of myeloperoxidase (MPO).
Anup Patnaik, Laura Axford, Lin Deng, Evan Cohick, Xianglin Ren, Jean B Regard

Bioorg Med Chem· June 2020

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Discovery of 1-((6-Aminopyridin-3-yl)Methyl)-3-(4-Bromophenyl)Urea as a Potent, Irreversible Myeloperoxidase Inhibitor.
Martin L Marro, Andrew W Patterson, Lac Lee, Lin Deng, Aimee Reynolds, Jean B Regard

J Pharmacol Exp Ther· October 2018

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Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion.
Miles Berger, David W Scheel, Hector Macias, Takeshi Miyatsuka, Hail Kim, Jean B Regard

Proc Natl Acad Sci U S A· March 2015

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Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification.
Jean B Regard, Deepti Malhotra, Jelena Gvozdenovic-Jeremic, Michelle Josey, Min Chen

Nat Med· November 2013

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Wnt signaling in bone development and disease: making stronger bone with Wnts.
Jean B Regard, Zhendong Zhong, Bart O Williams, Yingzi Yang

Cold Spring Harb Perspect Biol· December 2012

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Loss of vascular early response gene reduces edema formation after experimental stroke.
Fudong Liu, L Christine Turtzo, Jun Li, Jean Regard, Paul Worley

Exp Transl Stroke Med· June 2012

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Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia.
Jean B Regard, Natasha Cherman, Daniel Palmer, Sergei A Kuznetsov, Francesco S Celi

Proc Natl Acad Sci U S A· December 2011

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Local protease signaling contributes to neural tube closure in the mouse embryo.
Eric Camerer, Adrian Barker, Daniel N Duong, Rajkumar Ganesan, Hiroshi Kataoka, Jean B Regard

Dev Cell· January 2010

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Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice.
Eric Camerer, Jean B Regard, Ivo Cornelissen, Yoga Srinivasan, Daniel N Duong

J Clin Invest· July 2009

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Anatomical profiling of G protein-coupled receptor expression.
Jean B Regard, Isaac T Sato, Shaun R Coughlin

Cell· October 2008

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Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.
Jean B Regard, Hiroshi Kataoka, David A Cano, Eric Camerer, Liya Yin

J Clin Invest· December 2007

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Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate.
Rajita Pappu, Susan R Schwab, Ivo Cornelissen, João P Pereira, Jean B Regard

Science· April 2007

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Verge: a novel vascular early response gene.
Jean B Regard, Sigrid Scheek, Talaibek Borbiev, Anthony A Lanahan, Armin Schneider

J Neurosci· April 2004

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cDNA cloning of rabbit thrombomodulin and characterization of gene expression in cardiovascular tissue.
Clayton B Deming, Antony Y Kim, C E Bian, Jean B Regard, Jeffrey J Rade

DNA Seq· December 2003

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