Publications by authors named "Jeffri Retamal"

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Endosomal MrGPRX1 signaling sensitizes TRPV1 to enhance itch.
Paz Duran, Jeffri S Retamal, Marcella de Amorim Ferreira, Kai Trevett, Dane D Jensen

bioRxiv· November 2025

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N-methyl-D-aspartate receptor activation is downstream coupled to pannexin 1 opening by Src kinase in dorsal horn neurons: an essential link for mechanical hyperalgesia in nerve-injured rats.
Katherine Zepeda-Morales, David Bravo, Jonathan Aránguiz-Barrera, Estibaliz Ampuero, Georgina M Renard, Jeffri S Retamal

Pain· June 2025

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Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain.
Rocco Latorre, Paulina D Ramírez-Garcia, Alan Hegron, James L Grace, Jeffri S Retamal

Biomaterials· June 2022

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NMDA and P2X7 Receptors Require Pannexin 1 Activation to Initiate and Maintain Nociceptive Signaling in the Spinal Cord of Neuropathic Rats.
David Bravo, Katherine Zepeda-Morales, Carola J Maturana, Jeffri S Retamal, Alejandro Hernández

Int J Mol Sci· June 2022

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Mice expressing fluorescent PAR reveal that endocytosis mediates colonic inflammation and pain.
Rocco Latorre, Alan Hegron, Chloe J Peach, Shavonne Teng, Raquel Tonello, Jeffri S Retamal

Proc Natl Acad Sci U S A· February 2022

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Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice.
Francesco De Logu, Romina Nassini, Alan Hegron, Lorenzo Landini, Dane D Jensen, Jeffri Retamal

Nat Commun· February 2022

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A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes.
Quynh N Mai, Priyank Shenoy, Tim Quach, Jeffri S Retamal, Arisbel B Gondin

J Biol Chem· August 2021

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Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice.
Jeffri S Retamal, Megan S Grace, Larissa K Dill, Paulina Ramirez-Garcia, Scott Peng

Lab Invest· July 2021

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The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability.
Scott Peng, Megan S Grace, Arisbel B Gondin, Jeffri S Retamal, Larissa Dill

Lab Invest· August 2020

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A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain.
Paulina D Ramírez-García, Jeffri S Retamal, Priyank Shenoy, Wendy Imlach, Matthew Sykes

Nat Nanotechnol· December 2019

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Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain.
Jeffri S Retamal, Paulina D Ramírez-García, Priyank A Shenoy, Daniel P Poole, Nicholas A Veldhuis

Front Mol Neurosci· November 2019

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Burst-Like Subcutaneous Electrical Stimulation Induces BDNF-Mediated, Cyclotraxin B-Sensitive Central Sensitization in Rat Spinal Cord.
Jeffri Retamal, Andrea Reyes, Paulina Ramirez, David Bravo, Alejandro Hernandez

Front Pharmacol· October 2018

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Pannexin 1: a novel participant in neuropathic pain signaling in the rat spinal cord.
David Bravo, Paula Ibarra, Jeffri Retamal, Teresa Pelissier, Claudio Laurido

Pain· October 2014

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