Publications by authors named "Jennifer Iaci"

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Phase 2 study of zervimesine (CT1812) in participants with mild-to-moderate dementia with Lewy bodies (DLB).
James E Galvin, Magdalena I Tolea, Douglas W Scharre, Mary E Hamby, Jennifer F Iaci

Alzheimers Dement· December 2025

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Drug Development.
James E Galvin, Mary E Hamby, Jennifer Iaci, Michael Grundman, Anthony O Caggiano

Alzheimers Dement· December 2025

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Drug Development.
Michael Grundman, Susan Catalano, Mary E Hamby, Theresa Devins, Jennifer Iaci

Alzheimers Dement· December 2025

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Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury.
Ephron S Rosenzweig, Ernesto A Salegio, Justine J Liang, Janet L Weber, Chase A Weinholtz, Jennifer F Iaci

Nat Neurosci· August 2019

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Transient Changes in Hepatic Physiology That Alter Bilirubin and Bile Acid Transport May Explain Elevations in Liver Chemistries Observed in Clinical Trials of GGF2 (Cimaglermin Alfa).
Merrie Mosedale, Donald Button, Jonathan P Jackson, Kimberly M Freeman, Kenneth R Brouwer, Jennifer F Iaci

Toxicol Sci· February 2018

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Clinically Relevant Levels of 4-Aminopyridine Strengthen Physiological Responses in Intact Motor Circuits in Rats, Especially After Pyramidal Tract Injury.
Anil Sindhurakar, Asht M Mishra, Disha Gupta, Jennifer F Iaci, Tom J Parry

Neurorehabil Neural Repair· April 2017

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AC105 Increases Extracellular Magnesium Delivery and Reduces Excitotoxic Glutamate Exposure within Injured Spinal Cords in Rats.
Zhihong Huang, Zoran Filipovic, Nandakumar Mp, Chia Ung, Erika L Troy, Jennifer F Iaci

J Neurotrauma· February 2017

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Effects of neuregulin GGF2 (cimaglermin alfa) dose and treatment frequency on left ventricular function in rats following myocardial infarction.
Tom J Parry, Anindita Ganguly, Erika L Troy, J Luis Guerrero, Jennifer F Iaci

Eur J Pharmacol· February 2017

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The Evaluation of Magnesium Chloride within a Polyethylene Glycol Formulation in a Porcine Model of Acute Spinal Cord Injury.
Femke Streijger, Jae H T Lee, Neda Manouchehri, Elena B Okon, Seth Tigchelaar, Jennifer F Iaci

J Neurotrauma· December 2016

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A Phase I, Single Ascending Dose Study of Cimaglermin Alfa (Neuregulin 1β3) in Patients With Systolic Dysfunction and Heart Failure.
Daniel J Lenihan, Sarah A Anderson, Carrie Geisberg Lenneman, Evan Brittain, James A S Muldowney, Jennifer Iaci

JACC Basic Transl Sci· December 2016

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An optimized dosing regimen of cimaglermin (neuregulin 1β3, glial growth factor 2) enhances molecular markers of neuroplasticity and functional recovery after permanent ischemic stroke in rats.
Jennifer F Iaci, Tom J Parry, Zhihong Huang, Elias Pavlopoulos, Seth P Finklestein

J Neurosci Res· March 2016

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GGF2 is neuroprotective in a rat model of cavernous nerve injury-induced erectile dysfunction.
Arthur L Burnett, Sena F Sezen, Ahmet Hoke, Anthony O Caggiano, Jennifer Iaci

J Sex Med· April 2015

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Intravenous glial growth factor 2 (GGF2) isoform of neuregulin-1β improves left ventricular function, gene and protein expression in rats after myocardial infarction.
Michael F Hill, Amish V Patel, Abigail Murphy, Holly M Smith, Cristi L Galindo, Jennifer Iaci

PLoS One· August 2013

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Dalfampridine improves sensorimotor function in rats with chronic deficits after middle cerebral artery occlusion.
Jennifer F Iaci, Tom J Parry, Zhihong Huang, Seth P Finklestein, Jingmei Ren

Stroke· July 2013

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Glial growth factor 2 promotes functional recovery with treatment initiated up to 7 days after permanent focal ischemic stroke.
Jennifer F Iaci, Anindita Ganguly, Seth P Finklestein, Tom J Parry, Jingmei Ren

Neuropharmacology· December 2010

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Chondroitin sulfate proteoglycans in spinal cord contusion injury and the effects of chondroitinase treatment.
Jennifer F Iaci, Andrea M Vecchione, Michael P Zimber, Anthony O Caggiano

J Neurotrauma· November 2007

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