Publications by authors named "Jennifer Wortman"

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Comparability of Gastrointestinal Microbiome and Bile Acid Profiles in Patients With First or Multiply Recurrent Clostridioides difficile Infection.
Jessica A Bryant, Timothy J Straub, Darrell S Pardi, Kevin D Litcofsky, Colleen R Kelly, Jennifer Wortman

J Infect Dis· November 2025

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Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity.
Isabella C Glitza, Yongwoo David Seo, Christine N Spencer, Jennifer R Wortman, Elizabeth M Burton

Cancer Discov· July 2024

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Impact of a Purified Microbiome Therapeutic on Abundance of Antimicrobial Resistance Genes in Patients With Recurrent Clostridioides difficile Infection.
Timothy J Straub, Mary-Jane Lombardo, Jessica A Bryant, Liyang Diao, Thomas P Lodise, Jennifer R Wortman

Clin Infect Dis· April 2024

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SER-109, an Oral Microbiome Therapy for Recurrent Infection.
Paul Feuerstadt, Thomas J Louie, Bret Lashner, Elaine E L Wang, Liyang Diao, Jennifer R Wortman

N Engl J Med· January 2022

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SER-109, an Investigational Microbiome Drug to Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial.
Barbara H McGovern, Christopher B Ford, Matthew R Henn, Darrell S Pardi, Sahil Khanna, Jennifer R Wortman

Clin Infect Dis· June 2021

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A Phase 1b Safety Study of SER-287, a Spore-Based Microbiome Therapeutic, for Active Mild to Moderate Ulcerative Colitis.
Matthew R Henn, Edward J O'Brien, Liyang Diao, Brian G Feagan, William J Sandborn, Jennifer R Wortman

Gastroenterology· January 2021

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RNA-Seq Profile Reveals Th-1 and Th-17-Type of Immune Responses in Mice Infected Systemically with Aspergillus fumigatus.
Jata Shankar, Gustavo C Cerqueira, Jennifer R Wortman, Karl V Clemons, David A Stevens

Mycopathologia· August 2018

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Revitalization of a Forward Genetic Screen Identifies Three New Regulators of Fungal Secondary Metabolism in the Genus .
Brandon T Pfannenstiel, Xixi Zhao, Jennifer Wortman, Philipp Wiemann, Kurt Throckmorton

mBio· September 2017

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Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus.
Ronald P de Vries, Robert Riley, Ad Wiebenga, Guillermo Aguilar-Osorio, Sotiris Amillis, Jennifer Wortman

Genome Biol· February 2017

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Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks.
Gustavo C Cerqueira, Ashlee M Earl, Christoph M Ernst, Yonatan H Grad, John P Dekker, Jennifer R Wortman

Proc Natl Acad Sci U S A· January 2017

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Structure of the germline genome of and relationship to the massively rearranged somatic genome.
Eileen P Hamilton, Aurélie Kapusta, Piroska E Huvos, Shelby L Bidwell, Nikhat Zafar, Jennifer R Wortman

Elife· November 2016

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Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance.
Christopher A Desjardins, Keira A Cohen, Vanisha Munsamy, Thomas Abeel, Kashmeel Maharaj, Jennifer Wortman

Nat Genet· May 2016

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Genomic insights into the Ixodes scapularis tick vector of Lyme disease.
Monika Gulia-Nuss, Andrew B Nuss, Jason M Meyer, Daniel E Sonenshine, R Michael Roe, Jennifer R Wortman

Nat Commun· February 2016

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Toward a standard in structural genome annotation for prokaryotes.
H James Tripp, Granger Sutton, Owen White, Jennifer Wortman, Amrita Pati

Stand Genomic Sci· September 2015

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Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates from KwaZulu-Natal.
Keira A Cohen, Thomas Abeel, Abigail Manson McGuire, Christopher A Desjardins, Vanisha Munsamy, Jennifer Wortman

PLoS Med· September 2015

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Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement.
Bruce J Walker, Thomas Abeel, Terrance Shea, Margaret Priest, Amr Abouelliel, Jennifer Wortman

PLoS One· July 2015

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Standardized metadata for human pathogen/vector genomic sequences.
Vivien G Dugan, Scott J Emrich, Gloria I Giraldo-Calderón, Omar S Harb, Ruchi M Newman, Jennifer Wortman

PLoS One· February 2015

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Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus.
Jin Woo Bok, Philipp Wiemann, Graeme S Garvey, Fang Yun Lim, Brian Haas, Jennifer Wortman

BMC Genomics· November 2014

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The genomic diversification of the whole Acinetobacter genus: origins, mechanisms, and consequences.
Marie Touchon, Jean Cury, Eun-Jeong Yoon, Lenka Krizova, Gustavo C Cerqueira, Jennifer Wortman

Genome Biol Evol· October 2014

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Identification of 50 class D β-lactamases and 65 Acinetobacter-derived cephalosporinases in Acinetobacter spp.
Bruno Périchon, Sylvie Goussard, Violaine Walewski, Lenka Krizova, Gustavo Cerqueira, Jennifer Wortman

Antimicrob Agents Chemother· September 2014

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The Aspergillus Genome Database: multispecies curation and incorporation of RNA-Seq data to improve structural gene annotations.
Gustavo C Cerqueira, Martha B Arnaud, Diane O Inglis, Marek S Skrzypek, Gail Binkley, Jennifer R Wortman

Nucleic Acids Res· January 2014

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Kinannote, a computer program to identify and classify members of the eukaryotic protein kinase superfamily.
Jonathan M Goldberg, Allison D Griggs, Janet L Smith, Brian J Haas, Jennifer R Wortman

Bioinformatics· October 2013

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Emergence of epidemic multidrug-resistant Enterococcus faecium from animal and commensal strains.
François Lebreton, Willem van Schaik, Abigail Manson McGuire, Paul Godfrey, Allison Griggs, Jennifer Wortman

mBio· August 2013

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Genomics of Loa loa, a Wolbachia-free filarial parasite of humans.
Christopher A Desjardins, Gustavo C Cerqueira, Jonathan M Goldberg, Julie C Dunning Hotopp, Brian J Haas, Jennifer R Wortman

Nat Genet· May 2013

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Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae.
Diane O Inglis, Jonathan Binkley, Marek S Skrzypek, Martha B Arnaud, Gustavo C Cerqueira, Jennifer R Wortman

BMC Microbiol· April 2013

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