Publications by authors named "Jian-Xin Lin"

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STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity.
Jiajia Zhou, Kole Tison, Haibin Zhou, Longchuan Bai, Ranjan Kumar Acharyya, Linda Vatan, Heng Lin, Jian-Xin Lin

Nature· July 2025

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A new pipeline SPICE identifies novel JUN-IKZF1 composite elements.
Peng Li, Sree Pulugulla, Sonali Das, Jangsuk Oh, Rosanne Spolski, Jian-Xin Lin

Elife· January 2025

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TSLP acts on regulatory T cells to maintain their identity and limit allergic inflammation.
Rama K Gurram, Peng Li, Jangsuk Oh, Xi Chen, Rosanne Spolski, Jian-Xin Lin

Sci Immunol· January 2025

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Publisher Correction: Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells.
Jian-Xin Lin, Ning Du, Peng Li, Majid Kazemian, Tesfay Gebregiorgis

Nat Commun· January 2025

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A new pipeline SPICE identifies novel JUN-IKZF1 composite elements.
Peng Li, Sree H Pulugulla, Sonali Das, Jangsuk Oh, Rosanne Spolski, Jian-Xin Lin

bioRxiv· December 2024

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Publisher Correction: Strategies to therapeutically modulate cytokine action.
Warren J Leonard, Jian-Xin Lin

Nat Rev Drug Discov· November 2024

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Engineered cytokine/antibody fusion proteins improve IL-2 delivery to pro-inflammatory cells and promote antitumor activity.
Elissa K Leonard, Jakub Tomala, Joseph R Gould, Michael I Leff, Jian-Xin Lin

JCI Insight· September 2024

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LIM-domain-only 4 (LMO4) enhances CD8 T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.
Roland C Schelker, Jessica Fioravanti, Fabio Mastrogiovanni, Jeremy G Baldwin, Nisha Rana, Jian-Xin Lin

Signal Transduct Target Ther· August 2024

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Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation.
Jian-Xin Lin, Meili Ge, Cheng-Yu Liu, Ronald Holewinski, Thorkell Andresson

Nat Commun· August 2024

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Distinct use of super-enhancer elements controls cell type-specific CD25 transcription and function.
Rosanne Spolski, Peng Li, Vivek Chandra, Boyoung Shin, Shubham Goel, Jian-Xin Lin

Sci Immunol· November 2023

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Strategies to therapeutically modulate cytokine action.
Warren J Leonard, Jian-Xin Lin

Nat Rev Drug Discov· October 2023

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Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds.
Huilin Yang, Umut Y Ulge, Alfredo Quijano-Rubio, Zachary J Bernstein, David R Maestas, Jian-Xin Lin

Nat Chem Biol· September 2023

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Tetramerization of STAT5 regulates monocyte differentiation and the dextran sulfate sodium-induced colitis in mice.
Kelly L Monaghan, Wen Zheng, Halima Akhter, Lei Wang, Amanda G Ammer, Jian-Xin Lin

Front Immunol· May 2023

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Engineered cytokine/antibody fusion proteins improve delivery of IL-2 to pro-inflammatory cells and promote antitumor activity.
Elissa K Leonard, Jakub Tomala, Joseph R Gould, Michael I Leff, Jian-Xin Lin

bioRxiv· May 2023

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Publisher Correction: Potentiating adoptive cell therapy using synthetic IL-9 receptors.
Anusha Kalbasi, Mikko Siurala, Leon L Su, Mito Tariveranmoshabad, Lora K Picton, Jian-Xin Lin

Nature· December 2022

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The implications of IL-15 trans-presentation on the immune response.
Thomas A Waldmann, Robert Waldmann, Jian-Xin Lin, Warren J Leonard

Adv Immunol· November 2022

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PD-1 combination therapy with IL-2 modifies CD8 T cell exhaustion program.
Masao Hashimoto, Koichi Araki, Maria A Cardenas, Peng Li, Rohit R Jadhav, Jian-Xin Lin, Suresh S Ramalingam

Nature· October 2022

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Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency.
Robert Sertori, Jian-Xin Lin, Esteban Martinez, Sadhna Rana, Andrew Sharo

Front Immunol· August 2022

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Potentiating adoptive cell therapy using synthetic IL-9 receptors.
Anusha Kalbasi, Mikko Siurala, Leon L Su, Mito Tariveranmoshabad, Lora K Picton, Jian-Xin Lin

Nature· July 2022

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Impact of preoperative carbohydrate loading on gastric volume in patients with type 2 diabetes.
Xin-Qiang Lin, Yu-Ren Chen, Xiao Chen, Yu-Ping Cai, Jian-Xin Lin

World J Clin Cases· June 2022

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Tetramerization of STAT5 promotes autoimmune-mediated neuroinflammation.
Kelly L Monaghan, Drake Aesoph, Amanda G Ammer, Wen Zheng, Shokofeh Rahimpour, Jian-Xin Lin

Proc Natl Acad Sci U S A· December 2021

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An engineered IL-2 partial agonist promotes CD8 T cell stemness.
Fei Mo, Zhiya Yu, Peng Li, Jangsuk Oh, Rosanne Spolski, Jian-Xin Lin

Nature· September 2021

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Selective expansion of regulatory T cells using an orthogonal IL-2/IL-2 receptor system facilitates transplantation tolerance.
Toshihito Hirai, Teresa L Ramos, Po-Yu Lin, Federico Simonetta, Leon L Su, Jian-Xin Lin

J Clin Invest· April 2021

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Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8 T cell stemness and antitumor immunity.
Dalton Hermans, Sanjivan Gautam, Juan C García-Cañaveras, Daniel Gromer, Suman Mitra, Jian-Xin Lin

Proc Natl Acad Sci U S A· March 2020

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Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1 Stem-like CD8 T Cells during Chronic Infection.
William H Hudson, Julia Gensheimer, Masao Hashimoto, Andreas Wieland, Rajesh M Valanparambil, Jian-Xin Lin

Immunity· December 2019

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