Publications by authors named "John Joly"

Claim this Profile
D
Development of a targeted integration Chinese hamster ovary host directly targeting either one or two vectors simultaneously to a single locus using the Cre/Lox recombinase-mediated cassette exchange system.
Domingos Ng, Meixia Zhou, Dejin Zhan, Shirley Yip, Peggy Ko, John Joly

Biotechnol Prog· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development and characterization of an automated imaging workflow to generate clonally-derived cell lines for therapeutic proteins.
David Shaw, Mandy Yim, Joni Tsukuda, John C Joly, Andy Lin

Biotechnol Prog· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A strategy to accelerate protein production from a pool of clones in Chinese hamster ovary cells for toxicology studies.
Zhilan Hu, Wendy Hsu, Abby Pynn, Domingos Ng, Donna Quicho, John Joly

Biotechnol Prog· November 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Carboxypeptidase D is the only enzyme responsible for antibody C-terminal lysine cleavage in Chinese hamster ovary (CHO) cells.
Zhilan Hu, Henry Zhang, Benjamin Haley, Frank Macchi, Feng Yang, John C Joly

Biotechnol Bioeng· October 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Industry view on the relative importance of "clonality" of biopharmaceutical-producing cell lines.
Christopher Frye, Rohini Deshpande, Scott Estes, Kathy Francissen, John Joly

Biologicals· March 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effects of copper on CHO cells: cellular requirements and product quality considerations.
Inn H Yuk, Stephen Russell, Yun Tang, Wei-Ting Hsu, Jacob B Mauger, John C Joly

Biotechnol Prog· December 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fast identification of reliable hosts for targeted cell line development from a limited-genome screening using combined φC31 integrase and CRE-Lox technologies.
Yongping Crawford, Michelle Zhou, Zhilan Hu, John Joly, Brad Snedecor

Biotechnol Prog· May 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Complete knockout of the lactate dehydrogenase A gene is lethal in pyruvate dehydrogenase kinase 1, 2, 3 down-regulated CHO cells.
Shirley S M Yip, Meixia Zhou, John Joly, Bradley Snedecor, Amy Shen

Mol Biotechnol· September 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chinese hamster ovary K1 host cell enables stable cell line development for antibody molecules which are difficult to express in DUXB11-derived dihydrofolate reductase deficient host cell.
Zhilan Hu, Donglin Guo, Shirley S M Yip, Dejin Zhan, Shahram Misaghi, John C Joly

Biotechnol Prog· May 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Controlling glycation of recombinant antibody in fed-batch cell cultures.
Inn H Yuk, Boyan Zhang, Yi Yang, George Dutina, Kimberly D Leach, John C Joly

Biotechnol Bioeng· November 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases.
Meixia Zhou, Yongping Crawford, Domingos Ng, Jack Tung, Abigail F J Pynn, John Joly

J Biotechnol· April 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mechanisms of unintended amino acid sequence changes in recombinant monoclonal antibodies expressed in Chinese Hamster Ovary (CHO) cells.
Donglin Guo, Albert Gao, David A Michels, Lauren Feeney, Marian Eng, John Joly

Biotechnol Bioeng· September 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Proteomic profiling of recombinant Escherichia coli in high-cell-density fermentations for improved production of an antibody fragment biopharmaceutical.
Ilana S Aldor, Denise C Krawitz, William Forrest, Christina Chen, Julie C Nishihara, John C Joly

Appl Environ Microbiol· April 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High-level accumulation of a recombinant antibody fragment in the periplasm of Escherichia coli requires a triple-mutant (degP prc spr) host strain.
Christina Chen, Brad Snedecor, Julie C Nishihara, John C Joly, Nancy McFarland

Biotechnol Bioeng· March 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The cryptic ushA gene (ushA(c)) in natural isolates of Salmonella enterica (serotype Typhimurium) has been inactivated by a single missense mutation.
David Innes, Ifor R Beacham, Carie-Anne Beven, Meaghan Douglas, Michael W Laird, John C Joly

Microbiology (Reading)· July 2001

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis