Publications by authors named "Scott Estes"

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Therapeutic extracellular vesicle production is substantially increased by inhibition of cellular cholesterol biosynthesis.
Shelly Martin, Russell McConnell, Rane Harrison, Su Chul Jang, Chang Ling Sia, Scott Estes

Biotechnol Bioeng· September 2023

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Manufactured extracellular vesicles as human therapeutics: challenges, advances, and opportunities.
Scott Estes, Konstantin Konstantinov, Jamey D Young

Curr Opin Biotechnol· October 2022

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A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties.
Kevin Dooley, Russell E McConnell, Ke Xu, Nuruddeen D Lewis, Sonya Haupt, Scott Estes

Mol Ther· May 2021

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ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance.
Su Chul Jang, Kyriakos D Economides, Raymond J Moniz, Chang Ling Sia, Nuruddeen Lewis, Scott Estes

Commun Biol· April 2021

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Exosome Surface Display of IL12 Results in Tumor-Retained Pharmacology with Superior Potency and Limited Systemic Exposure Compared with Recombinant IL12.
Nuruddeen D Lewis, Chang Ling Sia, Katherine Kirwin, Sonya Haupt, Gauri Mahimkar, Scott Estes

Mol Cancer Ther· March 2021

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CHO genome mining for synthetic promoter design.
Yusuf B Johari, Adam J Brown, Christina S Alves, Yizhou Zhou, Chapman M Wright, Scott D Estes

J Biotechnol· March 2019

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Leveraging a CHO cell line toolkit to accelerate biotherapeutics into the clinic.
Chapman Wright, Christina Alves, Rashmi Kshirsagar, John Pieracci, Scott Estes

Biotechnol Prog· November 2017

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Human cell lines for biopharmaceutical manufacturing: history, status, and future perspectives.
Jennifer Dumont, Don Euwart, Baisong Mei, Scott Estes, Rashmi Kshirsagar

Crit Rev Biotechnol· December 2016

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A high-throughput capillary isoelectric focusing immunoassay for fingerprinting protein sialylation.
Lam Raga Anggara Markely, Lila Cheung, Young Jun Choi, Thomas Ryll, Scott Estes

Biotechnol Prog· November 2016

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Integration of cell line and process development to overcome the challenge of a difficult to express protein.
Christina S Alves, Alan Gilbert, Swati Dalvi, Bryan St Germain, Wenqi Xie, Scott Estes

Biotechnol Prog· August 2016

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Genetic mutation analysis at early stages of cell line development using next generation sequencing.
Chapman Wright, Joost Groot, Samantha Swahn, Helen McLaughlin, Mei Liu, Scott Estes

Biotechnol Prog· May 2016

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Industry view on the relative importance of "clonality" of biopharmaceutical-producing cell lines.
Christopher Frye, Rohini Deshpande, Scott Estes, Kathy Francissen, John Joly

Biologicals· March 2016

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Integrated cell and process engineering for improved transient production of a "difficult-to-express" fusion protein by CHO cells.
Yusuf B Johari, Scott D Estes, Christina S Alves, Marty S Sinacore, David C James

Biotechnol Bioeng· December 2015

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High-throughput ion exchange purification of positively charged recombinant protein in the presence of negatively charged dextran sulfate.
Lam Raga A Markely, Lutfiye Kurt, Janet Lau, Sarthak Mane, Bing Guan, Scott Estes

Biotechnol Prog· December 2014

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Mammalian cell line developments in speed and efficiency.
Scott Estes, Mark Melville

Adv Biochem Eng Biotechnol· June 2014

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Utilization of non-AUG initiation codons in a flow cytometric method for efficient selection of recombinant cell lines.
Victor R Cairns, Christine T DeMaria, Francis Poulin, José Sancho, Ping Liu, Scott Estes

Biotechnol Bioeng· November 2011

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Development of a simple and rapid method for producing non-fucosylated oligomannose containing antibodies with increased effector function.
Qun Zhou, Srinivas Shankara, Andre Roy, Huawei Qiu, Scott Estes

Biotechnol Bioeng· February 2008

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Accelerated clone selection for recombinant CHO CELLS using a FACS-based high-throughput screen.
Christine T DeMaria, Victor Cairns, Cordula Schwarz, Jin Zhang, Megan Guerin, Scott Estes

Biotechnol Prog· May 2007

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Activation of human acid sphingomyelinase through modification or deletion of C-terminal cysteine.
Huawei Qiu, Tim Edmunds, Jennifer Baker-Malcolm, Kenneth P Karey, Scott Estes

J Biol Chem· August 2003

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Tumors associated with oncogenic osteomalacia express genes important in bone and mineral metabolism.
Suzanne M Jan De Beur, Richard B Finnegan, John Vassiliadis, Brian Cook, Dana Barberio, Scott Estes

J Bone Miner Res· June 2002

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