Publications by authors named "John Meerman"

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High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability.
Steven Hiemstra, Sreenivasa C Ramaiahgari, Steven Wink, Giulia Callegaro, Maarten Coonen, John Meerman

Arch Toxicol· October 2019

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IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer.
Yinghui Zhang, Lynn Wester, Jichao He, Tamar Geiger, Marja Moerkens, John H N Meerman

Oncogene· April 2018

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Ultra high content image analysis and phenotype profiling of 3D cultured micro-tissues.
Zi Di, Maarten J D Klop, Vasiliki-Maria Rogkoti, Sylvia E Le Dévédec, Bob van de Water, John H N Meerman

PLoS One· December 2015

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Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity.
Lisa Fredriksson, Steven Wink, Bram Herpers, Giulia Benedetti, Mackenzie Hadi, John Meerman

Toxicol Sci· July 2014

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Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation.
Marja Moerkens, Yinghui Zhang, Lynn Wester, Bob van de Water, John H N Meerman

BMC Cancer· April 2014

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β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer.
Hoa H Truong, Jiangling Xiong, Veerander P S Ghotra, Ella Nirmala, Lizette Haazen, John H N Meerman

Sci Signal· February 2014

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Automated analysis of NF-κB nuclear translocation kinetics in high-throughput screening.
Zi Di, Bram Herpers, Lisa Fredriksson, Kuan Yan, Bob van de Water, John H N Meerman

PLoS One· July 2013

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The nuclear factor κB family member RelB facilitates apoptosis of renal epithelial cells caused by cisplatin/tumor necrosis factor α synergy by suppressing an epithelial to mesenchymal transition-like phenotypic switch.
Giulia Benedetti, Michiel Fokkelman, Kuan Yan, Lisa Fredriksson, Bram Herpers, John Meerman

Mol Pharmacol· July 2013

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TNF-α-mediated NF-κB survival signaling impairment by cisplatin enhances JNK activation allowing synergistic apoptosis of renal proximal tubular cells.
Giulia Benedetti, Lisa Fredriksson, Bram Herpers, John Meerman, Bob van de Water

Biochem Pharmacol· January 2013

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Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.
Jordi Carreras Puigvert, Louise von Stechow, Ramakrishnaiah Siddappa, Alex Pines, Mahnoush Bahjat, John H N Meerman

Sci Signal· January 2013

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Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes.
Yinghui Zhang, Marja Moerkens, Sreenivasa Ramaiahgari, Hans de Bont, Leo Price, John Meerman

Breast Cancer Res· May 2011

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Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells.
Carla S Verissimo, Jan J Molenaar, John Meerman, Jordi Carreras Puigvert, Fieke Lamers

Endocr Relat Cancer· June 2010

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Some nonylphenol isomers show antiestrogenic potency in the MVLN cell assay.
Thomas G Preuss, Hande Gurer-Orhan, John Meerman, Hans Toni Ratte

Toxicol In Vitro· February 2010

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Temporal and functional dynamics of the transcriptome during nerve growth factor-induced differentiation.
Thomas F Dijkmans, Lenneke W A van Hooijdonk, Theo G Schouten, Jessica T Kamphorst, Anette C A Vellinga, John H N Meerman

J Neurochem· June 2008

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Metabolic profiling of endocrine-disrupting compounds by on-line cytochrome p450 bioreaction coupled to on-line receptor affinity screening.
Sebastiaan M Van Liempd, Jeroen Kool, John H Meerman, Hubertus Irth, Nico P Vermeulen

Chem Res Toxicol· December 2007

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Online biochemical detection of glutathione-S-transferase P1-specific inhibitors in complex mixtures.
Jeroen Kool, Mark Eggink, Huub van Rossum, Sebastiaan M van Liempd, Danny A van Elswijk, John H N Meerman

J Biomol Screen· April 2007

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Screening the oxidative potential of several mono- and di-halogenated biphenyls and biphenyl ethers in rat hepatocytes.
Hande Gurer-Orhan, Hilme Orhan, Nico P Vermeulen, John H Meerman

Comb Chem High Throughput Screen· July 2006

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Rapid on-line profiling of estrogen receptor binding metabolites of tamoxifen.
Jeroen Kool, Rawi Ramautar, Sebastiaan M van Liempd, Joran Beckman, Frans J J de Kanter, John H N Meerman

J Med Chem· June 2006

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Quantification of urinary o,o'-dityrosine, a biomarker for oxidative damage to proteins, by high performance liquid chromatography with triple quadrupole tandem mass spectrometry. A comparison with ion-trap tandem mass spectrometry.
Hilmi Orhan, Stefan Coolen, John H N Meerman

J Chromatogr B Analyt Technol Biomed Life Sci· November 2005

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Bioactivation of dibrominated biphenyls by cytochrome P450 activity to metabolites with estrogenic activity and estrogen sulfotransferase inhibition capacity.
Marola M H van Lipzig, Jan N Commandeur, Frans J J de Kanter, Micaela C Damsten, Nico P E Vermeulen, John H N Meerman

Chem Res Toxicol· November 2005

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The chemical interaction between the estrogen receptor and monohydroxybenzo[a]pyrene derivatives studied by fluorescence line-narrowing spectroscopy.
Arjen N Bader, Maarten M van Dongen, Marola M H van Lipzig, Jeroen Kool, John H N Meerman

Chem Res Toxicol· September 2005

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Development of a novel cytochrome p450 bioaffinity detection system coupled online to gradient reversed-phase high-performance liquid chromatography.
Jeroen Kool, Sebastiaan M van Liempd, Rawi Ramautar, Tim Schenk, John H N Meerman

J Biomol Screen· August 2005

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Development and validation of a microsomal online cytochrome P450 bioreactor coupled to solid-phase extraction and reversed-phase liquid chromatography.
Sebastiaan M van Liempd, Jeroen Kool, Jelle Reinen, Tim Schenk, John H N a Meerman

J Chromatogr A· May 2005

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Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity.
Marola M H van Lipzig, Nico P E Vermeulen, Renato Gusinu, Juliette Legler, Heinz Frank, John H N Meerman

Environ Toxicol Pharmacol· January 2005

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Evaluation of a multi-parameter biomarker set for oxidative damage in man: increased urinary excretion of lipid, protein and DNA oxidation products after one hour of exercise.
Hilmi Orhan, Berry van Holland, Betty Krab, Janine Moeken, Nico P E Vermeulen, John H N Meerman

Free Radic Res· December 2004

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