Publications by authors named "Jonathan D Roth"

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Aberrant basement membrane production by HSCs in MASLD is attenuated by the bile acid analog INT-767.
Prakash Ramachandran, Madara Brice, Elena F Sutherland, Anna M Hoy, Eleni Papachristoforou, Jonathan D Roth

Hepatol Commun· December 2024

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Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH.
Maria Nicoline Baandrup Kristiansen, Sanne Skovgård Veidal, Christina Christoffersen, Michael Feigh, Niels Vrang, Jonathan David Roth

BMC Gastroenterol· December 2019

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Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH.
Jonathan D Roth, Sanne S Veidal, Louise K D Fensholdt, Kristoffer T G Rigbolt, Romeo Papazyan

Sci Rep· June 2019

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FXR activation by obeticholic acid or nonsteroidal agonists induces a human-like lipoprotein cholesterol change in mice with humanized chimeric liver.
Romeo Papazyan, Xueqing Liu, Jingwen Liu, Bin Dong, Emily M Plummer, Jonathan D Roth

J Lipid Res· June 2018

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INT-767 improves histopathological features in a diet-induced mouse model of biopsy-confirmed non-alcoholic steatohepatitis.
Jonathan D Roth, Michael Feigh, Sanne S Veidal, Louise Kd Fensholdt, Kristoffer T Rigbolt

World J Gastroenterol· January 2018

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Obese diet-induced mouse models of nonalcoholic steatohepatitis-tracking disease by liver biopsy.
Maria Nicoline Baandrup Kristiansen, Sanne Skovgård Veidal, Kristoffer Tobias Gustav Rigbolt, Kirstine Sloth Tølbøl, Jonathan David Roth

World J Hepatol· June 2016

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Amylin: Pharmacology, Physiology, and Clinical Potential.
Debbie L Hay, Steve Chen, Thomas A Lutz, David G Parkes, Jonathan D Roth

Pharmacol Rev· July 2015

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Simultaneous quantification of the glucagon-like peptide-1 (GLP-1) and cholecystokinin (CCK) receptor agonists in rodent plasma by on-line solid phase extraction and LC-MS/MS.
Yan Wang, Jonathan D Roth, Steven W Taylor

J Chromatogr B Analyt Technol Biomed Life Sci· April 2014

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Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment.
Jason R Clapper, Michelle D Hendricks, Guibao Gu, Carrie Wittmer, Carrie S Dolman, Jonathan D Roth

Am J Physiol Gastrointest Liver Physiol· October 2013

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Amylin and the regulation of appetite and adiposity: recent advances in receptor signaling, neurobiology and pharmacology.
Jonathan D Roth

Curr Opin Endocrinol Diabetes Obes· February 2013

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Effects of amylin and bupropion/naltrexone on food intake and body weight are interactive in rodent models.
Jason R Clapper, Jennifer Athanacio, Carrie Wittmer, Pete S Griffin, Lawrence D'Souza, Jonathan D Roth

Eur J Pharmacol· January 2013

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GLP-1R and amylin agonism in metabolic disease: complementary mechanisms and future opportunities.
Jonathan D Roth, Mary R Erickson, Steve Chen, David G Parkes

Br J Pharmacol· May 2012

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Glucagon-like peptide-1 receptor agonism improves metabolic, biochemical, and histopathological indices of nonalcoholic steatohepatitis in mice.
James L Trevaskis, Peter S Griffin, Carrie Wittmer, Brent A Neuschwander-Tetri, Elizabeth M Brunt, Jonathan D Roth

Am J Physiol Gastrointest Liver Physiol· April 2012

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Enhanced amylin-mediated body weight loss in estradiol-deficient diet-induced obese rats.
James L Trevaskis, Victoria F Turek, Carrie Wittmer, Peter S Griffin, Julie K Wilson, Jonathan D Roth

Endocrinology· December 2010

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"Weighing in" on synergy: preclinical research on neurohormonal anti-obesity combinations.
Jonathan D Roth, James L Trevaskis, Victoria F Turek, David G Parkes

Brain Res· September 2010

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Insights into amylin-leptin synergy.
James L Trevaskis, David G Parkes, Jonathan D Roth

Trends Endocrinol Metab· August 2010

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Noradrenergic neurons of the area postrema mediate amylin's hypophagic action.
Catarina S Potes, Victoria F Turek, Rebecca L Cole, Calvin Vu, Barbara L Roland, Jonathan D Roth

Am J Physiol Regul Integr Comp Physiol· August 2010

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Multi-hormonal weight loss combinations in diet-induced obese rats: therapeutic potential of cholecystokinin?
James L Trevaskis, Victoria F Turek, Peter S Griffin, Carrie Wittmer, David G Parkes, Jonathan D Roth

Physiol Behav· May 2010

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Interaction of leptin and amylin in the long-term maintenance of weight loss in diet-induced obese rats.
James L Trevaskis, Chunli Lei, Joy E Koda, Christian Weyer, David G Parkes, Jonathan D Roth

Obesity (Silver Spring)· January 2010

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Mechanisms of amylin/leptin synergy in rodent models.
Victoria F Turek, James L Trevaskis, Barry E Levin, Ambrose A Dunn-Meynell, Boman Irani, Jonathan D Roth

Endocrinology· January 2010

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It takes two to tango: combined amylin/leptin agonism as a potential approach to obesity drug development.
Jean L Chan, Jonathan D Roth, Christian Weyer

J Investig Med· October 2009

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Implications of amylin receptor agonism: integrated neurohormonal mechanisms and therapeutic applications.
Jonathan D Roth, Holly Maier, Steve Chen, Barbara L Roland

Arch Neurol· March 2009

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Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms.
James L Trevaskis, Todd Coffey, Rebecca Cole, Chunli Lei, Carrie Wittmer, Jonathan D Roth

Endocrinology· November 2008

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Hormone-based therapies in the regulation of fuel metabolism and body weight.
Nicole C Kesty, Jonathan D Roth, David Maggs

Expert Opin Biol Ther· November 2008

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Role of islet-, gut-, and adipocyte-derived hormones in the central control of food intake and body weight: implications for an integrated neurohormonal approach to obesity pharmacotherapy.
Hubert C Chen, Jonathan D Roth, Brock E Schroeder, Christian Weyer

Curr Diabetes Rev· May 2008

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