Publications by authors named "Jonathan Finn"

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Ligase-mediated programmable genomic integration (L-PGI).
Angela X Nan, Michael Chickering, Christopher L Bartolome, Neeta Shadija, Dan Li, Jonathan D Finn

Nat Commun· December 2025

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Development of circular AAV cargos for targeted seamless insertion with large serine integrases.
Brett J G Estes, Nisha Gandhi, Jessica R Von Stetina, Dev Paudel, Angela X Nan, Jonathan D Finn

Mol Ther Methods Clin Dev· June 2025

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Unlocking the potential of iPSC-derived immune cells: engineering iNK and iT cells for cutting-edge immunotherapy.
Minggang Fang, Alexander Allen, Chong Luo, Jonathan D Finn

Front Immunol· September 2024

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Therapeutic extracellular vesicle production is substantially increased by inhibition of cellular cholesterol biosynthesis.
Shelly Martin, Russell McConnell, Rane Harrison, Su Chul Jang, Chang Ling Sia, Jonathan Finn

Biotechnol Bioeng· September 2023

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Diagnosis and treatment outcomes from prebronchodilator spirometry performed alongside lung cancer screening in a Lung Health Check programme.
Claire Bradley, Alison Boland, Louisa Clarke, Naomi Dallinson, Claire Eckert, Jonathan Finn

Thorax· June 2023

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Transfection reagent artefact likely accounts for some reports of extracellular vesicle function.
Russell E McConnell, Madeleine Youniss, Bhargavee Gnanasambandam, Palak Shah, Wei Zhang, Jonathan D Finn

J Extracell Vesicles· October 2022

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A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties.
Kevin Dooley, Russell E McConnell, Ke Xu, Nuruddeen D Lewis, Sonya Haupt, Jonathan D Finn

Mol Ther· May 2021

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Evolutionary insights into coagulation factor IX Padua and other high-specific-activity variants.
Benjamin J Samelson-Jones, Jonathan D Finn, Leslie J Raffini, Elizabeth P Merricks, Rodney M Camire

Blood Adv· March 2021

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Timing of Intensive Immunosuppression Impacts Risk of Transgene Antibodies after AAV Gene Therapy in Nonhuman Primates.
Benjamin J Samelson-Jones, Jonathan D Finn, Patricia Favaro, J Fraser Wright, Valder R Arruda

Mol Ther Methods Clin Dev· June 2020

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Hyperactivity of factor IX Padua (R338L) depends on factor VIIIa cofactor activity.
Benjamin J Samelson-Jones, Jonathan D Finn, Lindsey A George, Rodney M Camire, Valder R Arruda

JCI Insight· June 2019

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A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing.
Jonathan D Finn, Amy Rhoden Smith, Mihir C Patel, Lucinda Shaw, Madeleine R Youniss

Cell Rep· February 2018

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Empty Capsids and Macrophage Inhibition/Depletion Increase rAAV Transgene Expression in Joints of Both Healthy and Arthritic Mice.
Caroline J Aalbers, Niels Broekstra, Mariska van Geldorp, Emiel Kramer, Sofia Ramiro, Jonathan D Finn

Hum Gene Ther· February 2017

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AAV liver expression of FIX-Padua prevents and eradicates FIX inhibitor without increasing thrombogenicity in hemophilia B dogs and mice.
Julie M Crudele, Jonathan D Finn, Joshua I Siner, Nicholas B Martin, Glenn P Niemeyer

Blood· March 2015

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Characterization of naturally-occurring humoral immunity to AAV in sheep.
Joseph Tellez, Kim Van Vliet, Yu-Shan Tseng, Jonathan D Finn, Nick Tschernia

PLoS One· July 2014

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Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes.
Daniel J Hui, Etiena Basner-Tschakarjan, Yifeng Chen, Robert J Davidson, George Buchlis, Jonathan D Finn

Mol Ther· September 2013

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Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells.
Ashley T Martino, Etiena Basner-Tschakarjan, David M Markusic, Jonathan D Finn, Christian Hinderer

Blood· March 2013

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The efficacy and the risk of immunogenicity of FIX Padua (R338L) in hemophilia B dogs treated by AAV muscle gene therapy.
Jonathan D Finn, Timothy C Nichols, Nikolaos Svoronos, Elizabeth P Merricks, Dwight A Bellenger

Blood· November 2012

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Safety of liver gene transfer following peripheral intravascular delivery of adeno-associated virus (AAV)-5 and AAV-6 in a large animal model.
Patricia Favaro, Jonathan D Finn, Joshua I Siner, J Fraser Wright, Katherine A High

Hum Gene Ther· July 2011

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In vivo genome editing restores haemostasis in a mouse model of haemophilia.
Hojun Li, Virginia Haurigot, Yannick Doyon, Tianjian Li, Sunnie Y Wong, Jonathan D Finn

Nature· June 2011

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CD8+ T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigen-presenting cells.
Jennifer D Bassett, Teng Chih Yang, Dannie Bernard, James B Millar, Stephanie L Swift, Jonathan D Finn

Blood· January 2011

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Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy.
Jonathan D Finn, Margareth C Ozelo, Denise E Sabatino, Helen W G Franck, Elizabeth P Merricks

Blood· December 2010

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Proteasome inhibitors decrease AAV2 capsid derived peptide epitope presentation on MHC class I following transduction.
Jonathan D Finn, Daniel Hui, Harre D Downey, Danielle Dunn, Gary C Pien

Mol Ther· January 2010

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Persistence of transgene expression influences CD8+ T-cell expansion and maintenance following immunization with recombinant adenovirus.
Jonathan D Finn, Jennifer Bassett, James B Millar, Natalie Grinshtein, Teng Chih Yang

J Virol· December 2009

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X-linked thrombophilia with a mutant factor IX (factor IX Padua).
Paolo Simioni, Daniela Tormene, Giulio Tognin, Sabrina Gavasso, Cristiana Bulato, Jonathan D Finn

N Engl J Med· October 2009

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Strategies to modulate immune responses: a new frontier for gene therapy.
Valder R Arruda, Patricia Favaro, Jonathan D Finn

Mol Ther· September 2009

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