Publications by authors named "Joseph Beyer"

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Balancing Efficacy and Safety of an Anti-DLL4 Antibody through Pharmacokinetic Modulation.
Jessica A Couch, Gu Zhang, Joseph C Beyer, Christina L Zuch de Zafra, Priyanka Gupta

Clin Cancer Res· March 2016

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Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.
Tanja S Zabka, Jatinder Singh, Preeti Dhawan, Bianca M Liederer, Jason Oeh, Joseph Beyer

Toxicol Sci· March 2015

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A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors.
Amita Patnaik, Patricia M LoRusso, Wells A Messersmith, Kyriakos P Papadopoulos, Lia Gore, Joseph C Beyer

Cancer Chemother Pharmacol· May 2014

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Immunogenicity/hypersensitivity of biologics.
Michael W Leach, James B Rottman, M Benjamin Hock, Deborah Finco, Jennifer L Rojko, Joseph C Beyer

Toxicol Pathol· January 2014

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Preclinical safety profile of trastuzumab emtansine (T-DM1): mechanism of action of its cytotoxic component retained with improved tolerability.
Kirsten Achilles Poon, Kelly Flagella, Joseph Beyer, Jay Tibbitts, Surinder Kaur

Toxicol Appl Pharmacol· December 2013

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An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides.
Cleopatra Kozlowski, Surinder Jeet, Joseph Beyer, Steve Guerrero, Justin Lesch

Dis Model Mech· May 2013

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Developmental immunotoxicology assessment of rituximab in cynomolgus monkeys.
Anu Vaidyanathan, Kathleen McKeever, Banmeet Anand, Steve Eppler, Gerhard F Weinbauer, Joseph C Beyer

Toxicol Sci· January 2011

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Toxicopathology of the developing immune system: investigative and development strategies.
Daniel Weinstock, David B Lewis, George A Parker, Joseph Beyer, Mark Collinge

Toxicol Pathol· December 2010

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Chronic DLL4 blockade induces vascular neoplasms.
Minhong Yan, Christopher A Callahan, Joseph C Beyer, Krishna P Allamneni, Gu Zhang

Nature· February 2010

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Alternative strategies for toxicity testing of species-specific biopharmaceuticals.
Jeanine L Bussiere, Pauline Martin, Michelle Horner, Jessica Couch, Meghan Flaherty, Joseph Beyer

Int J Toxicol· August 2009

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Pharmacokinetics and retinal distribution of ranibizumab, a humanized antibody fragment directed against VEGF-A, following intravitreal administration in rabbits.
Jacques Gaudreault, David Fei, Joseph C Beyer, Anne Ryan, Linda Rangell

Retina· April 2008

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Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade.
Wei Yu Lin, Qian Gong, Dhaya Seshasayee, Zhonghua Lin, Qinglin Ou, Joseph Beyer

Blood· December 2007

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Effect of intravitreal injection of ranibizumab in combination with verteporfin PDT on normal primate retina and choroid.
Ivana K Kim, Deeba Husain, Norman Michaud, Edward Connolly, Anne Marie Lane, Joseph C Beyer

Invest Ophthalmol Vis Sci· January 2006

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Depletion of B cells by a humanized anti-CD20 antibody PRO70769 in Macaca fascicularis.
Yulia Vugmeyster, Joseph Beyer, Kathy Howell, Dan Combs, Paul Fielder

J Immunother· October 2005

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Safety and efficacy of intravitreal injection of ranibizumab in combination with verteporfin PDT on experimental choroidal neovascularization in the monkey.
Deeba Husain, Ivana Kim, Danny Gauthier, Anne Marie Lane, Miltiadis K Tsilimbaris, Joseph C Beyer

Arch Ophthalmol· April 2005

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Evaluation of a surrogate antibody for preclinical safety testing of an anti-CD11a monoclonal antibody.
Janet Clarke, Will Leach, Susanne Pippig, Amita Joshi, Benjamin Wu, Joseph Beyer

Regul Toxicol Pharmacol· December 2004

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