Publications by authors named "Joseph D O'Connell"

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Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA(3)(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.
Janet Finer-Moore, Nadine Czudnochowski, Joseph D O'Connell, Amy Liya Wang, Robert M Stroud

J Mol Biol· December 2015

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Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer.
Brian C Monk, Thomas M Tomasiak, Mikhail V Keniya, Franziska U Huschmann, Joel D A Tyndall, Joseph D O'Connell

Proc Natl Acad Sci U S A· March 2014

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Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter.
John Edward Pak, Elisabeth Ngonlong Ekendé, Efrem G Kifle, Joseph Daniel O'Connell, Fabien De Angelis

Proc Natl Acad Sci U S A· November 2013

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Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells.
Anna Tochowicz, Sean Dalziel, Oliv Eidam, Joseph D O'Connell, Sarah Griner

J Med Chem· July 2013

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Structural context shapes the aquaporin selectivity filter.
David F Savage, Joseph D O'Connell, Larry J W Miercke, Janet Finer-Moore, Robert M Stroud

Proc Natl Acad Sci U S A· October 2010

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Metal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systems.
Fabien De Angelis, John K Lee, Joseph D O'Connell, Larry J W Miercke, Koen H Verschueren

Proc Natl Acad Sci U S A· June 2010

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A general protocol for the crystallization of membrane proteins for X-ray structural investigation.
Zachary E R Newby, Joseph D O'Connell, Franz Gruswitz, Franklin A Hays, William E C Harries

Nat Protoc· June 2009

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Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening.
Min Li, Franklin A Hays, Zygy Roe-Zurz, Linda Vuong, Libusha Kelly, Joseph D O'Connell

J Mol Biol· January 2009

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Architecture and selectivity in aquaporins: 2.5 a X-ray structure of aquaporin Z.
David F Savage, Pascal F Egea, Yaneth Robles-Colmenares, Joseph D O'Connell, Robert M Stroud

PLoS Biol· December 2003

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Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase.
Adrian T Keatinge-Clay, Anang A Shelat, David F Savage, Shiou Chuan Tsai, Larry J W Miercke, Joseph D O'Connell

Structure· February 2003

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