Publications by authors named "Juan Botas"

Claim this Profile
R
Revealing the nervous system requirements of Alzheimer disease risk genes in Drosophila.
Jennifer M Deger, Shabab B Hannan, Mingxue Gu, Colleen E Strohlein, Lindsey D Goodman, Juan Botas

Am J Hum Genet· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Basic Science and Pathogenesis.
David Li-Kroeger, Ismael Al-Ramahi, Nathaniel Smith, Aditi Marella, Bismark K Amoh, Juan Botas

Alzheimers Dement· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MeCP2 interacts with the super elongation complex to regulate transcription.
Jun Young Sonn, Wonho Kim, Marta Iwanaszko, Yuki Aoi, Yan Li, Juan Botas

Sci Adv· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Progressive Remodeling of Global Protein Interaction Networks in a Mouse Model of Tauopathy.
Weiwei Lin, Sadhna Phanse, Sophie J F van der Spek, Noah Lampl, Morgan C Stephens, Juan Botas

bioRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Revealing the nervous system requirements of Alzheimer's disease risk genes in .
Jennifer M Deger, Shabab B Hannan, Mingxue Gu, Colleen E Strohlein, Lindsey D Goodman, Juan Botas

bioRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multi-epitope immunocapture of huntingtin reveals striatum-selective molecular signatures.
Joshua L Justice, Todd M Greco, Josiah E Hutton, Tavis J Reed, Megan L Mair, Juan Botas

Mol Syst Biol· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease.
Morgan C Stephens, Jiayang Li, Megan Mair, Justin Moore, Katy Zhu, Juan Botas

Am J Hum Genet· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Longitudinal multi-omics in alpha-synuclein Drosophila model discriminates disease- from age-associated pathologies in Parkinson's disease.
Justin Moore, Timothy Wu, Justin Dhindsa, Omar El Fadel, Anh Le, Juan Botas

NPJ Parkinsons Dis· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genetic analysis of the X-linked Adrenoleukodystrophy in uncovers a role in Peroxisomal dynamics.
Joshua Manor, Sharayu V Jangam, Hyung-Lok Chung, Pranjali Bhagwat, Jonathan Andrews, Juan Botas

bioRxiv· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MeCP2 Interacts with the Super Elongation Complex to Regulate Transcription.
Jun Young Sonn, Wonho Kim, Marta Iwanaszko, Yuki Aoi, Yan Li, Juan Botas

bioRxiv· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SPA-STOCSY: an automated tool for identifying annotated and non-annotated metabolites in high-throughput NMR spectra.
Xu Han, Wanli Wang, Li-Hua Ma, Ismael Ai-Ramahi, Juan Botas

Bioinformatics· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional variants identify sex-specific genes and pathways in Alzheimer's Disease.
Thomas Bourquard, Kwanghyuk Lee, Ismael Al-Ramahi, Minh Pham, Dillon Shapiro, Juan Botas

Nat Commun· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.
Meigen Yu, Hui Ye, Ruth B De-Paula, Carl Grant Mangleburg, Timothy Wu, Juan Botas

PLoS Genet· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tau polarizes an aging transcriptional signature to excitatory neurons and glia.
Timothy Wu, Jennifer M Deger, Hui Ye, Caiwei Guo, Justin Dhindsa, Juan Botas

Elife· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An altered extracellular matrix-integrin interface contributes to Huntington's disease-associated CNS dysfunction in glial and vascular cells.
Sarah J Hernandez, Ryan G Lim, Tarik Onur, Mark A Dane, Rebecca Smith, Juan Botas

Hum Mol Genet· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evolutionarily conserved regulators of tau identify targets for new therapies.
Jiyoen Kim, Maria de Haro, Ismael Al-Ramahi, Lorena Laura Garaicoechea, Hyun-Hwan Jeong, Juan Botas

Neuron· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SPA-STOCSY: An Automated Tool for Identification of Annotated and Non-Annotated Metabolites in High-Throughput NMR Spectra.
Xu Han, Wanli Wang, Li-Hua Ma, Ismael Al-Ramahi, Juan Botas

bioRxiv· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes.
Jiayang Li, Bismark Kojo Amoh, Emma McCormick, Akash Tarkunde, Katy Fan Zhu, Juan Botas

Hum Mol Genet· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration.
Ron Benyair, Sai Srinivas Panapakkam Giridharan, Pilar Rivero-Ríos, Junya Hasegawa, Emily Bristow, Juan Botas

Autophagy Rep· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction: Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy.
Xiaodan Zhang, Xue Wen, Ismael Al-Ramahi, Juan Botas, Boxun Lu

Neurosci Bull· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of risk genes for Alzheimer's disease by gene embedding.
Yashwanth Lagisetty, Thomas Bourquard, Ismael Al-Ramahi, Carl Grant Mangleburg, Samantha Mota, Juan Botas

Cell Genom· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1.
Won-Seok Lee, Ismael Al-Ramahi, Hyun-Hwan Jeong, Youjin Jang, Tao Lin, Juan Botas

J Clin Invest· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease.
Todd M Greco, Christopher Secker, Eduardo Silva Ramos, Joel D Federspiel, Jeh-Ping Liu, Juan Botas

Cell Syst· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Suppression of toxicity of the mutant huntingtin protein by its interacting compound, desonide.
Haikun Song, Cen Wang, Chenggang Zhu, Ziying Wang, Huiya Yang, Juan Botas

Proc Natl Acad Sci U S A· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The developmental roots of neurodegeneration.
Morgan C Stephens, Vicky Brandt, Juan Botas

Neuron· January 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis