Publications by authors named "Kathryn D Tuttle"

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Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model.
Katherine A Waugh, Ross Minter, Jessica Baxter, Congwu Chi, Matthew D Galbraith, Kathryn D Tuttle

Nat Genet· June 2023

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JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome.
Kathryn D Tuttle, Katherine A Waugh, Paula Araya, Ross Minter, David J Orlicky

Cell Rep· November 2020

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Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity.
Paula Araya, Katherine A Waugh, Kelly D Sullivan, Nicolás G Núñez, Emiliano Roselli, Kathryn D Tuttle

Proc Natl Acad Sci U S A· November 2019

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Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors.
Rani K Powers, Rachel Culp-Hill, Michael P Ludwig, Keith P Smith, Katherine A Waugh, Kathryn D Tuttle

Nat Commun· October 2019

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Characterization of Thymic Development of Natural Killer T Cell Subsets by Multiparameter Flow Cytometry.
Kathryn D Tuttle, Laurent Gapin

Methods Mol Biol· February 2019

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TCR signal strength controls thymic differentiation of iNKT cell subsets.
Kathryn D Tuttle, S Harsha Krovi, Jingjing Zhang, Romain Bedel, Laura Harmacek

Nat Commun· July 2018

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Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function.
Srinivasan Sundararaj, Jingjing Zhang, S Harsha Krovi, Romain Bedel, Kathryn D Tuttle

Proc Natl Acad Sci U S A· February 2018

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T cell receptor recognition of CD1b presenting a mycobacterial glycolipid.
Stephanie Gras, Ildiko Van Rhijn, Adam Shahine, Tan-Yun Cheng, Mugdha Bhati, Kathryn D Tuttle

Nat Commun· October 2016

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Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors.
Daniel Silberman, Sai Harsha Krovi, Kathryn D Tuttle, James Crooks, Richard Reisdorph

Proc Natl Acad Sci U S A· September 2016

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Mutation of the Traj18 gene segment using TALENs to generate Natural Killer T cell deficient mice.
Jingjing Zhang, Romain Bedel, S Harsha Krovi, Kathryn D Tuttle, Bicheng Zhang

Sci Rep· June 2016

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Caspase-3 activation is required for reovirus-induced encephalitis in vivo.
J David Beckham, Kathryn D Tuttle, Kenneth L Tyler

J Neurovirol· July 2010

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